Results 131 to 140 of about 349,116 (315)

Medicinal Chemistry: Abstracts 490-506

open access: yesCHIMIA, 2011
Swiss Chemical Society
doaj   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Instructional Model to Teach Clinically Relevant Medicinal Chemistry [PDF]

open access: green, 2006
Naser Z. Alsharif   +4 more
openalex   +2 more sources

Poster Session 3 — Medicinal Chemistry [PDF]

open access: bronze, 2003
Fatemeh Hadizadeh   +6 more
openalex   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Medicinal Chemistry: Abstracts 63-97

open access: yesCHIMIA, 2006
Swiss Chemical Society
doaj   +1 more source

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