Results 181 to 190 of about 349,116 (315)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Structural insights, regulation, and recent advances of RAS inhibitors in the MAPK signaling cascade: a medicinal chemistry perspective. [PDF]

RSC Med Chem
Prajapati V, Singh AK, Kumar A, Singh H, Pathak P, Grishina M, Kumar V, Khalilullah H, Verma A, Kumar P.   +9 more
europepmc   +1 more source

Medicinal chemistry applied to a synthetic protein: Development of highly potent HIV entry inhibitors

, 2004
Oliver Hartley, Hubert Gaertner, Jill Wilken, Darren A. Thompson, Richard Fish, Alejandra Ramos, Cristina Pastore, Brigitte Dufour, Fabrice Cerini, Astrid Melotti, Nikolaus Heveker, Laurent Picard, Marc Alizon, Donald E. Mosier, Stephen B. H. Kent, Robin E. Offord   +15 more
openalex   +1 more source

2008 IUPAC–Richter Prize in Medicinal Chemistry: Call for Nominations [PDF]

, 2007

openalex   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Ponatinib: A Review of the History of Medicinal Chemistry behind Its Development. [PDF]

Pharmaceuticals (Basel)
Nascimento M, Moura S, Parra L, Vasconcellos V, Costa G, Leite D, Dias M, Fernandes TVA, Hoelz L, Pimentel L, Bastos M, Boechat N.   +11 more
europepmc   +1 more source

ACS excellence in biological, medicinal, and organic chemistry [PDF]

, 2007

openalex   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry. [PDF]

Pharmaceuticals (Basel)
Andreozzi G, Corvino A, Severino B, Magli E, Perissutti E, Frecentese F, Santagada V, Caliendo G, Fiorino F.   +8 more
europepmc   +1 more source

Medicinal Chemistry: Abstracts 280-357

CHIMIA, 2012
doaj   +1 more source