Results 181 to 190 of about 371,531 (327)
Human chitinases and chitinase-like proteins as emerging drug targets - a medicinal chemistry perspective. [PDF]
RSC Med ChemKurç Ö, Rähse N, Gohlke H, Cramer J.
europepmc +1 more source
Expanding Roles for Organoboron Compounds – Versatile and Valuable Molecules for Synthetic, Biological and Medicinal Chemistry [PDF]
, 2007 Nicos A. Petasis
openalex +1 more source
Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae) [PDF]
, 2007 Anita Brinker +3 more
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Medicinal chemistry breakthroughs on ATM, ATR, and DNA-PK inhibitors as prospective cancer therapeutics. [PDF]
J Enzyme Inhib Med ChemSharma R +7 more
europepmc +1 more source