Results 21 to 30 of about 30,936 (202)

Living kidney transplantation between brothers with unrecognized renal amyloidosis as the first manifestation of familial Mediterranean fever: a case report

BMC Medical Genetics, 2017
Background Familial Mediterranean fever is an autosomal recessive disease characterized by recurrent episodes of fever and polyserositis and by the onset of reactive amyloid-associated amyloidosis. Amyloidosis due to familial Mediterranean fever can lead
Ramón Peces, Sara Afonso, Carlos Peces, Julián Nevado, Rafael Selgas   +4 more
doaj   +1 more source

Early Post-transplant Recurrence of Amyloidosis in a Patient with Familial Mediterranean Fever

Turkish Journal of Nephrology, 2021
Familial Mediterranean fever is the most common hereditary auto-inflammatory disease characterized by a recurrent attack of fever and serositis. Untreated patients frequently develop AA type of amyloidosis which results in end-stage kidney disease (ESKD).
Deniz Aral Özbek, Neriman Sıla Koç, Arzu Sağlam, Tolga Yildirim, Şeref Rahmi Yilmaz, Yunus Erdem   +5 more
doaj   +1 more source

A patient with familial Mediterranean fever mimicking diarrhea-dominant irritable bowel syndrome who successfully responded to treatment with colchicine: a case report

Journal of Medical Case Reports, 2022
Background Irritable bowel syndrome is a functional gastrointestinal disease. Visceral hypersensitivity is the most important pathophysiology in irritable bowel syndrome. Currently, diagnosis of irritable bowel syndrome is based on symptoms and exclusion
Shima Kumei, Masatomo Ishioh, Yuki Murakami, Katsuyoshi Ando, Tsukasa Nozu, Toshikatsu Okumura   +5 more
doaj   +1 more source

A novel single variant in the MEFV gene causing Mediterranean fever and Behçet’s disease: a case report

Journal of Medical Case Reports, 2018
Background Familial Mediterranean fever is an autoinflammatory disease of unknown etiology, characterized clinically by recurrent attacks of sudden-onset fever with arthralgia and/or thoracoabdominal pain and pathogenetically by autosomal recessive ...
Maria Zerkaoui, Fatima Zahra Laarabi, Yousra Ajhoun, Bouchra Chkirate, Abdelaziz Sefiani   +4 more
doaj   +1 more source

Acute Recurrent Pericarditis as the Inaugural Manifestation of Familial Mediterranean Fever

European Journal of Case Reports in Internal Medicine, 2022
Familial Mediterranean fever (FMF) is an inherited autosomal recessive disorder commonly found among individuals of Mediterranean or Middle Eastern descent and caused by Mediterranean Fever gene (MEFV) mutations on chromosome 16.
Attout Hassene, Sofia Amichi, Hichem Bouhamla   +2 more
doaj   +1 more source

Biomimetic Nanoparticle Delivering Colchicine to Target Endothelial Inflammation for Atherosclerosis Treatment

Advanced NanoBiomed Research, EarlyView.
Platelet membrane‐coated layered double hydroxide nanoparticles were engineered to target inflamed endothelium at early‐stage atherosclerosis and enhance therapeutic efficacy. The biomimetic platform improves stability, immune escape, and inflamed vascular cell targeting, resulting in reduced oxidative stress and downregulated adhesion molecules.
Xiuwen Zhang, Lingqing Zong, Ashish Misra, Sanjay Patel, Zi Gu   +4 more
wiley   +1 more source

Characterizing MEFV gene variants in Jordanian patients with Familial Mediterranean Fever

Human Genomics
Background Familial Mediterranean Fever (FMF) is inherited as an autosomal recessive autoinflammatory disorder caused by mutations in the Mediterranean fever (MEFV) gene and predominantly affects populations from the Mediterranean region.
Wissam A. Alwazani, Nisreen A. Fuqaha, Zekrayat Medras, Yaqeen A. Rjoub, Kholoud Altaany   +4 more
doaj   +1 more source

A Case of Eosinophilic Esophagitis Accompanying Familial Mediterranean Fever

Case Reports in Gastrointestinal Medicine, 2017
Background. Eosinophilic esophagitis is an inflammatory condition where there is a dense infiltration of eosinophils typically exceeding fifteen cells per high power field.
Pejman Rohani, Mehri Najafi Sani, Mitra Ahmadi, Vahid Ziaee   +3 more
doaj   +1 more source

Mediterranean spotted fever as a cause of septic shock

IDCases, 2019
Mediterranean spotted fever is a generally benign disease but with the potential of serious manifestations.We report a case of Mediterranean spotted fever in a 56-year–old woman, with pet dog exposure, who presented with a septic shock pattern.
M. Abdeljelil, H. Sakly, I. Kooli, W. Marrakchi, A. Aouam, C. Loussaief, A. Toumi, H. Ben Brahim, M. Chakroun   +8 more
doaj   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source