Results 21 to 30 of about 14,042 (211)

The clinical significance of the Mediterranean fever gene MEFV variants in Castleman disease. [PDF]

Commun Med (Lond)
Idiopathic Multicentric Castleman Disease, Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Organomegaly (iMCD-TAFRO) is a rare cytokine storm syndrome with high mortality. Pathogenesis of Castleman disease (CD) remain largely unknown. We aim to unravel the role of Mediterranean fever gene MEFV variants, the key gene variants implicated in ...
Du Y, Xie S, Dai Z, Jia W, Li W, Zhang L, Du G, Zhang H, Lin Q, Wu M, Li Y, Yang W, Xiao J, Zhuansun Y, Li J, Zhang W, Jiang S, Nie D, Huang K.   +18 more
europepmc   +3 more sources

Vertebral artery dissection associated with familial Mediterranean fever and Behçet's disease [PDF]

Annals of Clinical and Translational Neurology, 2019
Vertebral artery dissection and recurrent meningitis are rare complications in Behçet's disease. Behçet's disease may be associated with familial Mediterranean fever.
Hidehiro Ishikawa, Akihiro Shindo, Yuichiro Ii, Shoko Sakano, Masaru Asahi, Keita Matsuura, Dai Kishida, Maki Umino, Masayuki Maeda, Hidekazu Tomimoto   +9 more
doaj   +2 more sources

Canakinumab as rescue therapy in familial Mediterranean fever refractory to conventional treatment

Drug Design, Development and Therapy, 2015
Mirella Alpa, Dario Roccatello Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare (CMID), Struttura Complessa Direzione Universitaria di Immunologia Clinica, Università di Torino e Ospedale G Bosco, Torino, ItalyAbstract ...
Alpa M, Roccatello D
doaj   +1 more source

The MEFV gene pathogenic variants and phenotype-genotype correlation in children with familial Mediterranean fever in the Çanakkale population

Balkan Journal of Medical Genetics, 2016
The aim of the current study was to determine the frequency of the Mediterranean fever (MEFV) gene pathogenic variants in 60 children diagnosed with familial Mediterranean fever (FMF) and to compare the phenotype-genotype correlation.
Battal F, Silan F, Topaloğlu N, Aylanç H, Yıldırım Ş, Köksal Binnetoğlu F, Tekin M, Kaymaz N, Ozdemir O   +8 more
doaj   +2 more sources

Reply to: "Hidradenitis suppurativa and Mediterranean fever gene mutations". [PDF]

JAAD Case Rep, 2019
Iannone M, Dini V, Oranges T.
europepmc   +5 more sources

Familial Mediterranean Fever: Current Approaches to Diagnosis and Treatment

Вопросы современной педиатрии, 2018
Familial Mediterranean fever is a typical monogenic disease with an autosomal recessive inheritance pattern; caused by mutations in the MEFV gene, which encodes the pyrin protein.
Mikhail M. Kostik, Olga V. Zhogova, Natalia V. Lagunova, Sergey V. Ivanovskiy, Oksana L. Kolobova, Larisa N. Melnikova   +5 more
doaj   +3 more sources

Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort study. [PDF]

EBioMedicine
Nakase H, Wagatsuma K, Kobayashi T, Matsumoto T, Esaki M, Watanabe K, Kunisaki R, Takeda T, Arai K, Ibuka T, Ishikawa D, Matsuno Y, Sakuraba H, Ueno N, Yokoyama K, Saruta M, Hokari R, Yokoyama J, Tamano S, Nojima M, Hisamatsu T, MEFV-IBDU Group.   +21 more
europepmc   +2 more sources

Autoinflammatory disease: clinical perspectives and therapeutic strategies

Inflammation and Regeneration, 2022
The molecular platforms of the innate immune system are essential to recognize pathologic external factors that are crucial to differentiate these danger signals from host motifs.
Atsushi Kawakami, Endo Yushiro, Koga Tomohiro, Yoshiura Koh-ichiro, Migita Kiyoshi   +4 more
doaj   +1 more source

Familial Mediterranean fever: issues of diagnosis and treatment

Лечащий Врач, 2023
Familial Mediterranean fever is an autoinflammatory genetically determined autosomal recessive disease caused by a mutation of the MEFV gene. Familial Mediterranean fever is recorded mainly in populations of Middle Eastern origin, historically inhabiting
G. R. Bikbavova, V. A. Akhmedov, T. V. Tretyakova, T. Yu. Panova   +3 more
doaj   +1 more source

A case report of a boy suffering from type 1 diabetes mellitus and familial Mediterranean fever

Italian Journal of Pediatrics, 2021
Background Type 1 diabetes mellitus could be associated with other autoimmune diseases, such as autoimmune thyroid disease, celiac disease, but the association with Familial Mediterranean Fever is rare, we describe a case of a boy with type 1 Diabetes ...
Maria Francesca Gicchino, Dario Iafusco, Angela Zanfardino, Emanuele Miraglia del Giudice, Alma Nunzia Olivieri   +4 more
doaj   +1 more source