Results 81 to 90 of about 14,042 (211)

Expression of the familial Mediterranean fever gene is regulated by nonsense-mediated decay† [PDF]

Human Molecular Genetics, 2009
Mutations in the MEditerranean FeVer (MEFV) gene are responsible for familial Mediterranean fever (FMF), a recessively inherited auto-inflammatory disease. Cases of dominant inheritance and phenotype-genotype heterogeneity have been reported; however, the underlying molecular mechanism is not currently understood.
Sylvie, Grandemange, Stephan, Soler, Isabelle, Touitou   +2 more
openaire   +2 more sources

Exploring the Nutraceutical Potential of Achillea millefolium L.: Phytochemical Composition, Biological Activities, and Industrial Applications

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Achillea millefolium Linn., commonly known as yarrow, is an extraordinary medicinal plant. A. millefolium has broad therapeutic potential due to its phytochemistry and essential oil composition. It possesses pharmacological properties, including antidiabetic, antioxidant, anti‐inflammatory, liver‐protective, antimicrobial, and gastroprotective effects,
Tooba Majeed, Muhammad Tauseef Sultan, Ahmad Mujtaba Noman, Hassan Raza, Hagar M. Mohamed, Nimra Anees, Muhammad Imran, Muzzamal Hussain, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Entessar Al Jbawi, Ehab M. Mostafa, Samy Selim, Ayman Salama, Mohamed A. Abdelgawad   +14 more
wiley   +1 more source

An adult case of atypical familial Mediterranean fever (pyrin‐associated autoinflammatory disease) similar to adult‐onset Still’s disease

Clinical Case Reports, 2019
Key Clinical Message We present a 55‐year‐old woman with periodic fever and symptoms similar to adult‐onset Still's disease (AOSD). She had a heterogeneous mutation of the MEFV gene and colchicine was effective.
Hayato Tsuruma, Hiroe Sato, Eriko Hasegawa, Yukiko Nozawa, Takeshi Nakatsue, Yoko Wada, Takeshi Kuroda, Yoshiki Suzuki, Masaaki Nakano, Ichiei Narita   +9 more
doaj   +1 more source

Identification of pathogenic MEFV variants in Korean patients with familial Mediterranean fever via whole-genome sequencing: a case report

Journal of Rheumatic Diseases
Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent episodes of fever, serositis, and arthritis. It is caused by variants in the MEFV gene, which encodes the pyrin protein.
Se Rim Choi, Christopher J. Yoon, Jeong Seok Lee, Young Seok Ju, Eun Young Lee   +4 more
doaj   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Familial Mediterranean fever in northwest of Iran (Ardabil): The first global report from Iran [PDF]

Familial Mediterranean fever (FMF), which is the prototype of the hereditary periodic fever syndromes, is common in the countries around the Mediterranean Sea. Considering its geographical position in the northwest of Iran, with its population of Turkish
فیضی, ایرج, خلفی, جعفر, صالح زاده, فرهاد, عظیمی, هرمز, ذولفقاری, علی اصغر, براک, منوچهر, جستان, مارینا, حبیب زاده, شهرام, امامی, دینا, یزدانبد, عباس, بشردوست, بهمن   +10 more
core  

Deciphering the full spectrum of Castleman diseases based on a cohort of 700 patients in a western country

British Journal of Haematology, Volume 208, Issue 6, Page 2036-2046, June 2026.
The spectrum of Castleman diseases has expanded over the past three decades. The phenotype of the diseases varies not only among the three major types but also according to the patient ancestry. Summary Under the Castleman disease (CD) eponym, three distinct diseases sharing common pathological features have been described over time.
Eric Oksenhendler, Marion Malphettes, Véronique Meignin, David Boutboul, Lionel Galicier   +4 more
wiley   +1 more source

A novel insertion mutation identified in exon 10 of the MEFV gene associated with Familial Mediterranean Fever

, 2014
Background: Familial Mediterranean Fever (FMF), characterized by recurrent fever and inflammation of serous membranes, is an autosomal recessive disease caused by mutations in the Mediterranean fever (MEFV) gene.
Hasan Dogan, Doğan, Hasan, Yildirim, Rahşan, Mevlit Ikbal, Tasdemir, Sener, Omer Atis, Mucahit Emet, Diyarbakir, Eda, Fatih Akdemir, Atis, Omer, Ikbal, Mevlit, Eda Diyarbakir, Rahsan Yildirim, Akdemir, Fatih, Sener Tasdemir, Emet, Mücahit   +15 more
core   +1 more source

Familial Mediterranean fever: current perspectives

, 2016
Hafize Emine Sönmez,* Ezgi Deniz Batu,* Seza ÖzenDepartment of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey *These authors contributed equally to this workAbstract: Familial Mediterranean fever (
Sönmez HE, Batu ED, Özen S
core  

Neurological Manifestations in Familial Mediterranean Fever: a Genotype-Phenotype Correlation Study

Background and Aims: Familial Mediterranean Fever (FMF) is a periodic auto-inflammatory disease with an autosomal recessive hereditary pattern. The aim of this study is to explain the spectrum of possible neurological manifestations and its genotype ...
مرتضایی, مریم, احمدآبادی, فرزاد, صالح زاده, فرهاد, نعمت دوست حقی, رقیه, اعظمی, احد   +4 more
core   +1 more source