Results 91 to 100 of about 729,280 (261)

The Medium of Instruction Policy in Nepal: Towards Critical Engagement on the Ideological and Pedagogical Debate

open access: yesJournal of Language and Education, 2019
Although there were attempts to develop multilingual and multicultural education in Nepal, changes have remained more discursive than pragmatic at the working level. Problems discussed have remained unsolved. The issues of protection and promotion of the
Prem Prasad Poudel
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

ENGLISH MEDIUM INSTRUCTION IN THE PRIVATE UNIVERSITIES IN BANGLADESH

open access: yesIndonesian Journal of Applied Linguistics, 2013
: As it is viewed English Medium Instruction (EMI) at tertiary level has emerged as a big educational issue in Bangladesh as well as many parts of the world.
Monjurul Islam
doaj   +1 more source

E-LEARING [PDF]

open access: yes
Electronic learning (or e-Learning or eLearning) is a type of Technology supported education/learning (TSL) where the medium of instruction is through computer technology, particularly involving digital technologies.
El Baaboua Florentina, Titrade Cristina
core  

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