Results 111 to 120 of about 173,378,546 (253)
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
A blended learning model for English Medium Instruction in higher education
, 2013 English Medium Instruction (EMI) learning is at an early exploratory stage in Tai Wan higher education (HE). EMI is where students are taught their discipline in an English only context.
Wei, Yin (R17459), Han, Jinghe (R16321)
core
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Dataset de Students’ performance and English as a medium of instruction: Do students learn less?
Obra relacionada: García-Álvarez de Perea, J., & Ramírez-García, C. (2024). Students’ performance and English as a medium of instruction: Do students learn less? Language Teaching Research, 0(0).
García Álvarez de Perea, Juan +1 more
core +1 more source
Researching English-medium instruction at Swedish universities
, 2018 Sweden is continuously ranked high among the countries offering English-medium instruction. The country also ranks high in terms of its general proficiency in English but the use of this language in higher education and research has not been ...
Maria Kuteeva, Kuteeva, Maria,
core +1 more source
English as the Medium of Instruction
, 2020 English is undeniably the lingua franca of the world today and it has become a big part of education on a global scale. Higher education (HE) worldwide is increasingly seeking to internationalise their institutions through the implementation of English as a medium of instruction (EMI).
openaire +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source