Results 101 to 110 of about 732,819 (307)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Multilingual medium of instruction towards an inclusive curriculum

open access: yesNamibian Journal of Linguistics, Literature and Communication Studies
This study investigates the potential benefits of adopting a multilingual medium of instruction in Namibian schools in comparison to China's multilingual educational model. In Namibia, where English is the medium of instruction from grades 4 to 12, many
Salomo Ndeyamunye Ndeshimona
doaj   +1 more source

MOTHER TONGUE-BASED BILINGUAL EDUCATION PRACTICE FOR TEACHING PRIMARY MATHEMATICS IN RURAL SCHOOL [PDF]

open access: yes, 2015
In an ethnically diverse country like Malaysia, educators often argue about the best medium of instruction to be used in teaching mathematics especially in primary school.
Alvinson, Roland Demong   +4 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

ENGLISH MEDIUM INSTRUCTION IN THE PRIVATE UNIVERSITIES IN BANGLADESH

open access: yesIndonesian Journal of Applied Linguistics, 2013
: As it is viewed English Medium Instruction (EMI) at tertiary level has emerged as a big educational issue in Bangladesh as well as many parts of the world.
Monjurul Islam
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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