Results 91 to 100 of about 16,846 (220)

Cancer IDO1‐Mediated Tryptophan–Kynurenine Metabolic Reprogramming to Drive Skeletal Muscle Atrophy and Cachexia Acceleration

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Cancer cachexia is a debilitating syndrome characterized by severe skeletal muscle wasting, which significantly impairs patient quality of life and survival. Indoleamine 2,3‐dioxygenase 1 (IDO1), a key enzyme in tryptophan (Trp) metabolism, is often upregulated in cancers, but its specific role in driving lung cancer–associated ...
Leng Han, Lingjie Jing, Xinting Zhu, Ciqin Li, Lu Bai, Yang Fang, Yuxuan Zhou, Dingyuan Bai, Jin Lu, Yonglong Han, Cheng Guo, Shumin Zhou, Quanjun Yang   +12 more
wiley   +1 more source

Fatty Liver Index Shows Poor Discrimination for MRI‐Measured Hepatic Steatosis in African Compared with European Adults

Liver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT Background and Aim The Fatty Liver Index (FLI) is a proxy for hepatic steatosis, but its performance against magnetic resonance imaging (MRI) is unknown in African populations. We evaluated the discriminatory performance of the FLI for detecting hepatic steatosis in European men (EM) and West African men (WAM) in the UK, and Black South ...
Asanda Mtintsilana, Kwazi Gabuza, Melony C. Fortuin‐de Smidt, Jon Hauksson, Oluwatoyosi Bello, Olah Hakim, Gráinne Whelehan, Tommy Olsson, Louise M. Goff, Julia H. Goedecke   +9 more
wiley   +1 more source

Depot medroxyprogesterone acetate discontinuation after weight gain in 17-19 year old adolescent girls

, 2002
Depot medroxyprogesterone acetate (DMPA) is a long acting progesterone only contraceptive agent. Side effects such as irregular bleeding patterns and weight gain are attributed to discontinuation.
Church, Donna Lea
core  

Trends in Maternal Mortality in Bhutan: A National Review, 1985 to 2024

Reproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Background Maternal mortality remains a major global public health concern, with the highest burden in low‐ and middle‐income countries. Despite global progress, preventable causes such as hemorrhage and hypertensive disorders continue to contribute significantly to maternal deaths.
Yeshey Dorjey, Deep Kiran Chhetri, Thinley Dorji, Sonam Gyamtsho   +3 more
wiley   +1 more source

Heavy Menstrual Bleeding: Experiences and Learnings From Patient Survey

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 3, June 2026.
ABSTRACT Background Heavy menstrual bleeding (HMB) affects 1 in 4 women. It is often debilitating for those experiencing it, resulting in negative impacts on quality of life. Prompted by a national call for better insights into the management of HMB, the authors sought to collect patient feedback regarding access to HMB treatment alongside satisfaction
Mikaela Jacka, Madeleine Ward, Katrina Guerin, Russell Dalton   +3 more
wiley   +1 more source

The Incidence of Negative Laparoscopy for Pelvic Pain Stratified by Level of Training and Location of Service Provision

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 3, June 2026.
ABSTRACT Aim Systematic reduction of negative laparoscopy for pelvic pain is crucial to reducing surgical morbidity, improving diagnostic accuracy and minimising cost. This study aims to determine the incidence and consider the underlying causes of negative laparoscopy in women presenting with pelvic pain.
Akshara Shyamsunder, Cecilia Ng, Zaynab El‐Hamawi, David Krones, Erin Nesbitt‐Hawes, Rebecca Deans, Jason Abbott   +6 more
wiley   +1 more source

Depot medroxyprogesterone acetate (DMPA)-associated early-onset osteoporotic fracture

Endocrinology, Diabetes & Metabolism Case Reports
Depot medroxyprogesterone acetate (DMPA) is a highly effective injectable contraceptive, but is associated with reduced bone mineral density (BMD) and increased fracture risk in some studies because it inhibits the hypothalamic–pituitary–ovarian axis ...
Yotsapon Thewjitcharoen, Veekij Veerasomboonsin, Soontaree Nakasatien, Thep Himathongkam   +3 more
doaj   +1 more source

Pulmonary Lymphangioleiomyomatosis: A Case Report in Postmenopausal Woman Treated with Pleurodesis and Progesterone (Medroxyprogesterone Acetate)

, 1996
The main problem in the treatment of pulmonary lymphangioleiomyomatosis, which frequently occurs in the reproductive age, is the control of chylothorax and disease progression.
Mario Lise, Alida Zanella, Paola Toppan, Donato Nitti   +3 more
core   +1 more source

Immunomodulatory Role of Natural Progesterone in Pregnancy: A Review

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 6, June 2026.
ABSTRACT Aim Pregnancy complications such as miscarriage, preterm birth (PTB), and luteal phase defects (LPD) are significant reproductive health issues globally, with both physical and psychological implications. This review aims to examine the role of natural progesterone in pregnancy‐related disorders, specifically threatened and recurrent ...
Prakash Mehta, Hemant Deshpande, Anjali Deshpande, Reshma Quadros, Shruti Dharmadhikari, Chintan Khandhedia, Gaurav Puppalwar, Amey Mane, Suyog Mehta   +8 more
wiley   +1 more source

A case report and literature review: A 19‐year‐old with endometrial carcinoma treated with medroxyprogesterone acetate. Importance of the medical interview and endometrial examination

Clinical Case Reports
Key Clinical Message A 19‐year‐old woman had stage IA endometrial carcinoma treated with medroxyprogesterone acetate and experienced a recurrence. This patient's experience illustrates the importance of a thorough history and endometrial assessment in ...
Shinichiro Katsuma, Kazuya Ariyoshi, Ai Nio, Kenichi Taguchi, Kenzo Sonoda   +4 more
doaj   +1 more source