Results 171 to 180 of about 13,589 (222)

Depot Medroxyprogesterone Acetate

2020
Depot medroxyprogesterone acetate (DMPA) is an injectable progestin-only contraceptive administered every 13 weeks. DMPA is an extremely effective contraceptive agent when used consistently. With typical use, approximately 6 out of 100 women will become pregnant in the first year of use, reflecting that some users do not return for repeat injections ...
Deanna C. McCullough, Kathryn M. Eraso, Andrew M. Kaunitz   +2 more
openaire   +1 more source

Medroxyprogesterone Acetate and Sleep Apnea

Psychiatry and Clinical Neurosciences, 1987
Abstract: Seven patients with sleep apnea DOES and one with sleep apnea DIMS were treated with medroxyprogesterone acetate (MPA). The therapeutic effect was confirmed in most of them by polysomnographic recording. A marked increase of TST was observed in two patients whose AI and/or %SAT remarkably decreased.
openaire   +2 more sources

A potential mechanism in medroxyprogesterone acetate teratogenesis

Teratology, 1979
AbstractMedroxyprogesterone acetate (MPA) has been shown to be teratogenic in rabbits but not in rats or mice (Andrew and Staples, 1977). Since normal steroid action appears to be mediated, in large part, through interaction with specific steroid receptors, we postulated that the species difference in teratogenicity might be due to a difference in the ...
G L, Kimmel, B S, Hartwell, F D, Andrew
openaire   +2 more sources

The Response of the Bitch to Treatment with Medroxyprogesterone Acetate

Journal of Small Animal Practice, 1967
Abstract— —Medroxyprogesterone acetate (M.A.P.) was administered to three groups of bitches as follows: Eighty‐six bitches received a total of 166 injections of M.A.P. to prevent or suppress oestrus. This procedure was entirely successful in 83 bitches (96.5 per cent) and partially successful or unsuccessful in the remaining 3 bitches.
A R, Withers, J C, Whitney
openaire   +2 more sources

GLC Determination of Medroxyprogesterone Acetate in Plasma

Journal of Pharmaceutical Sciences, 1974
To study the absorption, metabolism, and excretion of medroxyprogesterone acetate in animals and man, a method was developed for measurement of the intact drug in plasma based on: (a) cyclohexane extraction of the specimen, (b) formation of the 3-enol heptafluorobutyrate ester, and (c) quantification via GLC using an electron-capture detector.
D G, Kaiser, R G, Carlson, K T, Kirton
openaire   +2 more sources

Toxicology of depot medroxyprogesterone acetate

Contraception, 1994
Depo-Provera (depot-medroxyprogesterone acetate or DMPA), administered either subcutaneously or intramuscularly, has undergone a thorough toxicological evaluation in a number of animal species. DMPA has been tested in short- and long-term toxicity studies in rodents, rabbits, and monkeys.
openaire   +2 more sources

The Contraceptive Use of Depot Medroxyprogesterone Acetate

Clinical Obstetrics and Gynecology, 1995
Depot medroxyprogesterone acetate (DMPA) was the first popular long-acting progestogen-only contraceptive and is used by more than nine million women worldwide. It is one of the most convenient and effective yet readily reversible methods of contraception.
M, Hickey, I, Fraser
openaire   +2 more sources

Treatment of Breast Cancer with Medroxyprogesterone Acetate

Annals of Internal Medicine, 1968
The prolonged administration of large doses of medroxyprogesterone acetate (MPA) in the treatment of patients with disseminated breast cancer was studied. The patients consisted of 17 postmenopausal women previously treated with 1 or more hormones (group I) 17 women (oophorectomized or postnatural menopause) who had received MPA prior to the study ...
F M, Muggia, P A, Cassieth, M, Ochoa, F A, Flatow, A, Gellhorn, G A, Hyman   +5 more
openaire   +2 more sources

Augmentation of exercise ventilation by medroxyprogesterone acetate

Clinical Physiology, 1982
Summary. The influence of medroxyprogesterone acetate (MPA) on exercise performance was studied in a double‐blind cross‐over trial using six normal males to compare the exercise performance changes to those observed in a previous study of exercise responses of female subjects during the follicular and luteal phase of the menstrual cycle.
H T, Robertson, R B, Schoene, D J, Pierson   +2 more
openaire   +2 more sources

CONTRACEPTIVE AND ENDOMETRIAL EFFECTS OF MEDROXYPROGESTERONE ACETATE

Obstetrical & Gynecological Survey, 1969
Present means of contraception are not satisfactory for all women. This study reports on the contraception efficacy and menstrual abnormalities of medroxyprogesterone acetate (Depo-Provera), which was given in an intramuscular dose of 150 mg. every 3 months for 1 year.
openaire   +2 more sources