Clival Chondrosarcoma Associated With an Intra-Axial Cystic Medullary Lesion Responsive to Steroids
Introduction: Here we present a 75-year-old patient who was admitted with acute-onset right-sided hemiparesis, dysphagia, dysarthria and nystagmus. Repeated MRI scans showed two lesions with contact to one another: one solid stationary extra-axial lesion
Johannes Walter+5 more
doaj +1 more source
Differences in Clinical Characteristics Between Missed and Detected Laryngopharyngeal Cancers
ABSTRACT Background and aim Laryngopharyngeal cancers are often overlooked during endoscopy because of their anatomical complexity and the gag reflex. However, the characteristics of these cancers remain poorly understood. We studied the differences in clinical characteristics and endoscopic procedures between missed and detected cancers. Methods Newly
Yusuke Kumazawa+14 more
wiley +1 more source
Distribution of α7 Nicotinic Acetylcholine Receptor Subunit mRNA in the Developing Mouse. [PDF]
Homomeric α7 nicotinic acetylcholine receptors (nAChRs) are abundantly expressed in the central and peripheral nervous system (CNS and PNS, respectively), and spinal cord.
Broide, Ron S+3 more
core +1 more source
Familial adult-onset Alexander disease with a novel mutation (D78N) in the glial fibrillary acidic protein gene with unusual bilateral basal ganglia involvement [PDF]
In this report, we describe the case of a new Japanese family (32 to 64years old; 2 females and 1 male) affected by adult-onset Alexander disease. Clinically, one member (age at onset, 56years old) developed cerebellar ataxia, another (age at onset ...
Namekawa, Michito+3 more
core +1 more source
Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli+12 more
wiley +1 more source
Combined cerebellar and bilateral cervical posterior spinal artery stroke demonstrated on MRI [PDF]
Combined cerebellar and spinal ischemic stroke is a rare, critical condition. We report a patient with combined cerebellar and bilateral posterolateral cervical spinal cord infarction due to bilateral stenosis of the vertebral arteries. MRI is the method
Brückmann, H.+5 more
core +1 more source
Effects of gestational intermittent hypoxia on maternal, fetal and offspring respiratory system. In black, effects in humans; in red, in vitro effects; in blue, effects in animal models. Summary Obstructive sleep apnea (OSA) is a common sleep disorder that is associated with a wide variety of health conditions, including cardiovascular, cerebrovascular,
Esther Valverde‐Pérez+4 more
wiley +1 more source
Unprecedented Combination of Rare Degenerative Pathologies in an Octogenarian Ex‐Football Player
ABSTRACT A 79‐year‐old former professional football player presented with language deficits and cognitive changes. A year later, he had difficulty completing sentences, and 3 years after onset, was reduced to one‐word answers. He developed severe apathy and agitation, and became more impulsive.
Shelley L. Forrest+6 more
wiley +1 more source
Enteric neuropathy and the vagus nerve: Therapeutic implications
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source
Prepontine non-giant neurons drive flexible escape behavior in zebrafish [PDF]
Many species execute ballistic escape reactions to avoid imminent danger. Despite fast reaction times, responses are often highly regulated, reflecting a trade-off between costly motor actions and perceived threat level.
Bergeron, S.+4 more
core +2 more sources