Results 131 to 140 of about 125,156 (180)
Some of the next articles are maybe not open access.
Medullary thyroid cancer - An update
Best Practice & Research Clinical Endocrinology & Metabolism, 2023Medullary thyroid cancer (MTC) is a rare neuroendocrine disease, encompassing about 5% of all thyroid cancers. Due to its peculiar features, this rare tumour offers unique possibilities for translational research studies. It arises from neuroendocrine parafollicular cells in an endocrine organ, and appears as a nodule apparently indistinguishable from ...
openaire +3 more sources
Management of Medullary Thyroid Cancer
Endocrinology and Metabolism Clinics of North America, 2019Medullary thyroid cancer (MTC) is rare but aggressive. It can be cured only if intrathyroid at diagnosis. MTC can be sporadic (75%) or familial (25%) and the 2 forms are distinguished by RET mutations analysis. Calcitonin is the specific serum marker; its doubling time is the most important prognostic factor for survival and progression; 30% of MTC ...
Viola, David, Elisei, Rossella
openaire +3 more sources
Update on Medullary Thyroid Cancer
Endocrinology and Metabolism Clinics of North America, 2014Medullary thyroid carcinoma (MTC) is a rare type of thyroid cancer, demonstrating variable behavior from indolent disease to highly aggressive, progressive disease. There are distinguishing phenotypic features of sporadic and hereditary MTC. Activation or overexpression of cell surface receptors and up-regulation of intracellular signaling pathways in ...
Mimi I, Hu +2 more
openaire +2 more sources
Medullary cancer of the breast revisited
Breast Cancer Research and Treatment, 1990Common as well as unusual, heretofore unmentioned histopathologic features observed in 336 typical and 273 atypical medullary breast cancers from 6404 patients enrolled in various stage I and II protocols of the National Surgical Adjuvant Breast and Bowel Projects (NSABP) are presented.
E R, Fisher +5 more
openaire +2 more sources
Surgical Clinics of North America, 1995
Medullary thyroid cancer is a tumor of the thyroid C cells that occurs in sporadic and hereditary clinical settings. Genetic testing of at-risk individuals is available and has been applied to patient management. Plasma calcitonin levels are a very sensitive marker for the presence of disease.
openaire +2 more sources
Medullary thyroid cancer is a tumor of the thyroid C cells that occurs in sporadic and hereditary clinical settings. Genetic testing of at-risk individuals is available and has been applied to patient management. Plasma calcitonin levels are a very sensitive marker for the presence of disease.
openaire +2 more sources
Medullary and non-medullary thyroid cancer in a family
Acta Oncologica, 2004We report an unusual family which suggests that susceptibility to medullary and non-medullary thyroid cancer (MTC, NMTC) may be related. The index case, a woman aged 59, presented with a 3 cm nodule in the right lobe of her thyroid gland. Thyroid function tests were within normal limits. The patient’s past medical history was unremarkable. Furthermore,
Audrey Ardern-jones +6 more
openaire +1 more source
The Extent of Surgery for Thyroid Medullary Cancer
Tumori Journal, 1994Aims Evaluation of the impact of the extent of primary surgery and reintervention on the outcome of patients with medullary thyroid carcinoma. Methods Seventy-two patients with medullary thyroid carcinoma (MTC) were surgically treated ...
Pelizzo M. R. +8 more
openaire +4 more sources
Endocrine Abstracts, 2015
Medullary thyroid cancer (MTC) is an uncommon disease, accounting for 3–10 % of all thyroid cancers worldwide [1–3]. The German literature contains reports of a thyroid malignancy with amyloid deposits as early as 1906, but it was not until 1959 when Hazard and co-workers reported on a clinicopathological, solid arrangement of cells, which represented ...
Laura Chin-Lenn, Janice L. Pasieka
openaire +2 more sources
Medullary thyroid cancer (MTC) is an uncommon disease, accounting for 3–10 % of all thyroid cancers worldwide [1–3]. The German literature contains reports of a thyroid malignancy with amyloid deposits as early as 1906, but it was not until 1959 when Hazard and co-workers reported on a clinicopathological, solid arrangement of cells, which represented ...
Laura Chin-Lenn, Janice L. Pasieka
openaire +2 more sources
Sporadic Medullary Thyroid Cancer
2009Medullary thyroid cancer (MTC), is a tumor of the parafollicular / c-cells of the thyroid gland. These cells are derived from the embryonic neural crests and make up 1% of the thyroid cells. C-cells can be found anywhere in the gland but are concentrated in the upper poles of the thyroid lobes.
Adrian, Harvey, Janice L, Pasieka
openaire +2 more sources
2021
In this chapter while following the clinical course of a patient diagnosed with medullary thyroid cancer (MTC), the reader will be acquainted with the basic clinical features, diagnosis, and treatment of this rare tumor.
openaire +1 more source
In this chapter while following the clinical course of a patient diagnosed with medullary thyroid cancer (MTC), the reader will be acquainted with the basic clinical features, diagnosis, and treatment of this rare tumor.
openaire +1 more source