Results 91 to 100 of about 3,418,065 (230)

Targeted Therapy for Medullary Thyroid Cancer: A Review

Frontiers in Oncology, 2017
Medullary thyroid cancers (MTCs) constitute between 2 and 5% of all thyroid cancers. The 10-year overall survival (OS) rate of patients with localized disease is around 95% while that of patients with regional stage disease is about 75%.
S. R. Priya, S. R. Priya, Chandra Shekhar Dravid, Chandra Shekhar Dravid, Raghunadharao Digumarti, Raghunadharao Digumarti, Mitali Dandekar   +6 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Expression of cholecystokinin-B/gastrin receptors in medullary thyroid cancer

, 1999
To characterise the cholecystokinin (CCK) receptor subtypes in medullary thyroid cancer by measuring the expression of CCK-A and CCK-B/gastrin receptor ...
Nilsson, Ola,, Wängberg, Bo,, Forssell-Aronsson, Eva,, Ahlman, Håkan,, Tisell, Lars-Eric,, Lundberg, P A, Lindstedt, G, Amiri-Mosavi, A, Kölby, Lars,   +8 more
core   +1 more source

GLP‐1 Receptor Agonists and Cancer Risk in Obesity Treatment

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a well‐established risk factor for numerous cancers, with body habitus, especially central adiposity, contributing to increased cancer incidence and worse prognosis. Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs), initially developed to treat Type 2 diabetes, have rapidly gained prominence as powerful anti‐obesity agents due ...
Lorne J. Hofseth, E. Angela Murphy, Mary C. Playdon, Liza Makowski, Anna R. Ibele, Ciaran M. Fairman, James R. Hebert   +6 more
wiley   +1 more source

Medullary thyroid cancer (MTC): Risk Factors for Recurrence and Prognostic Variables that Influence Outcome

SVU - International Journal of Medical Sciences
Background: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor from thyroid C cells that can cause thyroid lumps or metastases. MTC accounts for 10.5% of metastasized thyroid tumors and is linked to RET proto-oncogene mutations.
Ayman A. Amin , Hamdy Mohamed Hussein , Ahmed K. Fekry *, Mohamed Mubarak   +3 more
doaj   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Combination chemotherapy with 5-fluorouracil and dacarbazine in advanced medullary thyroid cancer, a possible alternative?

, 2017
Combination chemotherapy with 5-fluorouracil and dacarbazine in advanced medullary thyroid cancer, a possible ...
Françoise Descotes (366487), Françoise Borson-Chazot (2743144), Lucien Marchand (2743147), Cécile Nozières (2743141), Myriam Decaussin-Petrucci (2743129), Claire Bournaud (2743135), Thomas Walter (221641), Marie-Odile Joly (2743138), Véronique Lapras (2743132)   +8 more
core   +1 more source

Animal models of medullary thyroid cancer: State of the art and view to the future [PDF]

, 2017
Medullary thyroid carcinoma is a neuroendocrine tumour originating from parafollicular C cells accounting for 5-10% of thyroid cancers. Increased understanding of diseasespecific molecular targets of therapy has led to the regulatory approval of two ...
A. Bassi, G. Vitale, A. Faggiano, Faggiano, Antongiulio, Vitale, Giovanni, Circelli, Luisa, M. F. Manzoni, Vitale Giovanni, Gaudenzi, Germano, Fioritti, Niccolò, Fioritti Niccolò, Manzoni, Marco F., Gaudenzi Germano, Colao Annamaria, G. Gaudenzi, Faggiano Antongiulio, Manzoni Marco F, L. Circelli, A. A. Colao, Circelli Luisa, Bassi Andrea, N. Fioritti, BASSI, ANDREA, Colao, Annamaria, Manzoni, Marco F   +24 more
core   +1 more source

Pathologic Characterization and Clinical Significance of Lymphovascular Invasion in Canine Thyroid Carcinomas

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT The association between lymphovascular invasion (LVI) and outcomes in dogs with thyroid carcinoma is inadequately described, and a standardized definition of LVI is lacking. This study's objectives were to histopathologically and immunohistochemically characterize LVI and to evaluate associated clinical outcomes in dogs with thyroid carcinoma.
Maureen A. Griffin, Brianna Stoyle, Allie Oakes, Brian Flesner, Jennifer A. Lenz, Darko Stefanovski, Amy C. Durham   +6 more
wiley   +1 more source

Uncommon metastatic journey: unusual breast metastases of medullary thyroid carcinoma: a case report

BMC Women's Health
Medullary thyroid carcinoma is a neuroendocrine tumor derived from thyroid C-cells. It is a rare aggressive tumor, known to metastasize to lymph nodes, liver, bones, and lungs.
Saadallah Fatma, Chrigui Maha, Zemni Ines, Kammoun Salma, Houcin Yoldez, Jbeli Souhail, Driss Maha, Ben Dhiab Tarak   +7 more
doaj   +1 more source