Results 91 to 100 of about 146,670 (267)

Cabozantinib for progressive metastatic medullary thyroid cancer: a review

Therapeutics and Clinical Risk Management, 2014
Joshua R Colombo, Richard O Wein Department of Otolaryngology, Head and Neck Surgery, Tufts Medical Center, Boston, MA, USA Abstract: Medullary thyroid cancer is uncommon and patients typically present with advanced disease.
Colombo JR, Wein RO
doaj  

Polycythemia after vandetanib treatment in metastatic medullary thyroid carcinoma: A rare case report

Current Problems in Cancer: Case Reports, 2020
Medullary thyroid cancer is a neuroendocrine tumor of the thyroid gland and its frequency is 1–2% among all thyroid cancers. Their prognosis is poor with a 10-year survival rate of 40%.
Yusuf Ilhan, Hasan Senol Coskun, Unal Atas, Sema Sezgin Goksu   +3 more
doaj   +1 more source

Synergistic antitumour activity of RAF265 and ZSTK474 on human TT medullary thyroid cancer cells [PDF]

, 2015
Medullary thyroid cancer (MTC) is an aggressive malignancy responsible for up to 14% of all thyroid cancer-related deaths. It is characterized by point mutations in the rearranged during transfection (RET) proto-oncogene.
Barollo, Susi, Bertazza, Loris, Boscaro, Marco, Cavedon, Elisabetta, Faggian, Diego, Mian, Caterina, Pelizzo, MARIA ROSA, Pezzani, Raffaele, Plebani, Mario, Radu, CLAUDIA-MARIA, Rubin, Beatrice, Simioni, Paolo   +11 more
core   +1 more source

ACR‐TIRADS Institution and Effect on Thyroid Surgeries in Veterans: A 10‐Year Retrospective Study

The Laryngoscope, EarlyView.
Following analysis of the adoption of ACR TI‐RADS at the VA Northern California Healthcare System, the number of thyroid ultrasounds and FNAs increased substantially, while the total number of thyroid surgeries remained relatively stable. Surgical practice trends towards more selective and less‐invasive management, with fewer total thyroidectomies for ...
Isabella W. Leon, Davis S. Chong, Bryle Nicole G. Barrameda, Anusha A. Gogulapati, Lane D. Squires   +4 more
wiley   +1 more source

Molecular Diagnostics in Thyroid Nodules: Current Applications, Clinical Value, and Future Perspective

Med Research, EarlyView.
ABSTRACT Molecular diagnostics have become an important adjunct to ultrasonography and fine‐needle aspiration (FNA) for thyroid nodules, especially in Bethesda III/IV cytology where malignancy risk is uncertain. This narrative review summarizes the diagnostic and prognostic value of key genomic drivers (BRAF V600E, RAS, RET, TERT, and selected fusions)
Guohui Xiao, Min Ding, Zhixue Min, Yihan Dong, Xuanye Cao, Qiang Lu, Cong Chen, Yahui Wu, Xin Guo, Zhen Wu, Jing Xie, Dan Xu, Haizhen Chen, Rongli Xie, Jian Fei   +14 more
wiley   +1 more source

Cohexisting Medullary and Papillary Thyroid Cancer [PDF]

, 2017
Purpose: Papillary thyroid carcinomas (PTCs) and medullary thyroid carcinomas (MTCs) have always been considered different in terms of their incidence rates, cell origins, and histopathological features.
Dionigi, G., Inversini, D., La Rosa, S., Lavazza, M., Pappalardo, V., Piantanida, E., Sessa, F., Tanda, ML, Uccella, S., Xiaoli, L.   +9 more
core   +2 more sources

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Significance of laboratory markers in the diagnosis and postoperative monitoring of patients with medullary thyroid cancer

Кубанский научный медицинский вестник, 2014
The histologic picture of the medullary cancer can resemble a papillary and follicular cancer that takes away doctors towards the wrong statement of the diagnosis.
L. A. Ivanova, O. N. Rostovtseva, L. S. Malygina, A. N. Pakhomova, J. M. Gavrilova, A. S. Klimova   +5 more
doaj  

Calcitonin negative Medullary Thyroid Carcinoma: a challenging diagnosis or a medical dilemma?

BMC Endocrine Disorders, 2019
Background Medullary thyroid carcinoma is a neuroendocrine tumor belonging form a malignant growth of the thyroid parafollicular C-cells, representing from 1 to 10% of all thyroid cancer.
Claudio Gambardella, Chiara Offi, Renato Patrone, Guglielmo Clarizia, Claudio Mauriello, Ernesto Tartaglia, Francesco Di Capua, Sergio Di Martino, Roberto Maria Romano, Lorenzo Fiore, Alessandra Conzo, Giovanni Conzo, Giovanni Docimo   +12 more
doaj   +1 more source

Familial Medullary Thyroid Cancer: Five-year Review of the Most Frequent Mutations in the RET Gene: An Update

Sudan Journal of Medical Sciences, 2022
Background: Familial Medullary Thyroid Cancer (FMTC) is hereditary in 25% of cases. Patients with an inherited form of FMTC usually have a germline mutation in the RET proto-oncogene (10q11.2); these mutations generally occur in exons 10 (codons 618 and ...
Blanca Estela Díaz Castañeda, Mariela Eulogio Vences, Brian Emmanuel Díaz Gordillo, Miriam Deyanira Rodríguez Piña, Hugo Mendieta Zerón   +4 more
doaj   +1 more source