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Current Treatment Options in Oncology, 2000
Patients with clinically evident medullary thyroid cancer should have a total extracapsular thyroidectomy with bilateral central neck dissection and an ipsilateral prophylactic or therapeutic modified (functional) radical neck dissection when the primary tumor is greater than 1 cm and when the central neck nodes are positive.
E, Kebebew, O H, Clark
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Patients with clinically evident medullary thyroid cancer should have a total extracapsular thyroidectomy with bilateral central neck dissection and an ipsilateral prophylactic or therapeutic modified (functional) radical neck dissection when the primary tumor is greater than 1 cm and when the central neck nodes are positive.
E, Kebebew, O H, Clark
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Otolaryngologic Clinics of North America, 2003
Medullary thyroid cancer is a rare neoplasm that arises from the parafollicular C cells. It occurs in a sporadic form, or less commonly as a hereditary form, as part of multiple endocrine neoplasia syndromes types 2A and 2B. The RET proto-oncogene is currently the primary factor that is implicated in the hereditary forms of this neoplasm. The knowledge
Gary L, Clayman, Tarek S, el-Baradie
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Medullary thyroid cancer is a rare neoplasm that arises from the parafollicular C cells. It occurs in a sporadic form, or less commonly as a hereditary form, as part of multiple endocrine neoplasia syndromes types 2A and 2B. The RET proto-oncogene is currently the primary factor that is implicated in the hereditary forms of this neoplasm. The knowledge
Gary L, Clayman, Tarek S, el-Baradie
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Medullary thyroid cancer - An update
Best Practice & Research Clinical Endocrinology & Metabolism, 2023Medullary thyroid cancer (MTC) is a rare neuroendocrine disease, encompassing about 5% of all thyroid cancers. Due to its peculiar features, this rare tumour offers unique possibilities for translational research studies. It arises from neuroendocrine parafollicular cells in an endocrine organ, and appears as a nodule apparently indistinguishable from ...
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Update on Medullary Thyroid Cancer
Endocrinology and Metabolism Clinics of North America, 2014Medullary thyroid carcinoma (MTC) is a rare type of thyroid cancer, demonstrating variable behavior from indolent disease to highly aggressive, progressive disease. There are distinguishing phenotypic features of sporadic and hereditary MTC. Activation or overexpression of cell surface receptors and up-regulation of intracellular signaling pathways in ...
Mimi I, Hu +2 more
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The Extent of Surgery for Thyroid Medullary Cancer
Tumori Journal, 1994Aims Evaluation of the impact of the extent of primary surgery and reintervention on the outcome of patients with medullary thyroid carcinoma. Methods Seventy-two patients with medullary thyroid carcinoma (MTC) were surgically treated ...
Pelizzo M. R. +8 more
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Endocrine Abstracts, 2015
Medullary thyroid cancer (MTC) is an uncommon disease, accounting for 3–10 % of all thyroid cancers worldwide [1–3]. The German literature contains reports of a thyroid malignancy with amyloid deposits as early as 1906, but it was not until 1959 when Hazard and co-workers reported on a clinicopathological, solid arrangement of cells, which represented ...
Laura Chin-Lenn, Janice L. Pasieka
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Medullary thyroid cancer (MTC) is an uncommon disease, accounting for 3–10 % of all thyroid cancers worldwide [1–3]. The German literature contains reports of a thyroid malignancy with amyloid deposits as early as 1906, but it was not until 1959 when Hazard and co-workers reported on a clinicopathological, solid arrangement of cells, which represented ...
Laura Chin-Lenn, Janice L. Pasieka
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Surgical Clinics of North America, 1995
Medullary thyroid cancer is a tumor of the thyroid C cells that occurs in sporadic and hereditary clinical settings. Genetic testing of at-risk individuals is available and has been applied to patient management. Plasma calcitonin levels are a very sensitive marker for the presence of disease.
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Medullary thyroid cancer is a tumor of the thyroid C cells that occurs in sporadic and hereditary clinical settings. Genetic testing of at-risk individuals is available and has been applied to patient management. Plasma calcitonin levels are a very sensitive marker for the presence of disease.
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2013
Medullary thyroid cancer is rare, in 25 % of cases genetically determined (multiple endocrine neoplasia type 2), and should be treated by a specialized multidisciplinary team in the Cancer Center. In most cases, total thyroidectomy and at least central compartment lymph node dissection are required.
Tanima Jana +2 more
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Medullary thyroid cancer is rare, in 25 % of cases genetically determined (multiple endocrine neoplasia type 2), and should be treated by a specialized multidisciplinary team in the Cancer Center. In most cases, total thyroidectomy and at least central compartment lymph node dissection are required.
Tanima Jana +2 more
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Sporadic Medullary Thyroid Cancer
2009Medullary thyroid cancer (MTC), is a tumor of the parafollicular / c-cells of the thyroid gland. These cells are derived from the embryonic neural crests and make up 1% of the thyroid cells. C-cells can be found anywhere in the gland but are concentrated in the upper poles of the thyroid lobes.
Adrian, Harvey, Janice L, Pasieka
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DeckerMed CGSO Case-Based Reviews, 2018
Medullary thyroid cancer (MTC) arises from the thyroid C-cells and accounts for 1 to 2% of thyroid cancers in the United States. Most tumors are sporadic but may occur as a part of the familial syndromes multiple endocrine neoplasia (MEN) 2A, MEN2B, and familial MTC.
Ganapathi Bantwal, Vivek Mathew
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Medullary thyroid cancer (MTC) arises from the thyroid C-cells and accounts for 1 to 2% of thyroid cancers in the United States. Most tumors are sporadic but may occur as a part of the familial syndromes multiple endocrine neoplasia (MEN) 2A, MEN2B, and familial MTC.
Ganapathi Bantwal, Vivek Mathew
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