Results 101 to 110 of about 3,418,065 (230)

Kinase inhibitors in thyroid cancers

Endocrine Oncology
Objective: The treatment landscape for thyroid cancers has changed rapidly with the availability of kinase inhibitors against VEGFR, BRAF, MEK, NTRK, and RET.
Vineeth Sukrithan, Prachi Jain, Manisha H Shah, Bhavana Konda   +3 more
doaj   +1 more source

Indication and Timing of Thyroid Surgery for Patients with Hereditary Medullary Thyroid Cancer Syndromes

, 2006
Hereditary medullary thyroid cancer syndromes comprise familial medullary thyroid cancer (FMTC) and multiple endocrine neoplasia types 2A and 2B. Hereditary medullary thyroid cancers have an autosomal dominant pattern of inheritance and are caused by ...
Electron Kebebew, Jennifer B. Ogilvie
core   +1 more source

Integrated single‐cell transcriptomics reveals miR‐941 targets CLDN4 to inhibit malignant progression of thyroid cancer through the PI3K/AKT signaling pathway

Journal of Cell Communication and Signaling, Volume 20, Issue 4, December 2026.
The combined single‐cell and functional analysis depicts that miR‐941 targets CLDN4 and activates the regulatory axis that drives the malignancy of thyroid cancer through the PI3K/AKT pathway. Abstract Claudin‐4 (CLDN4), a key tight junction protein, has been implicated in tumor progression; however, its functional role and regulatory mechanisms in ...
Jinghua Zhou, Tiancheng Fu, Guoxiang Huang, Guangfeng Luo, Chengcheng Wang, Yanze Wang, Ziyang Ding, Xiarong Hu, Yudong Li, Zhen Li   +9 more
wiley   +1 more source

ROLE OF IL-4 AND IL-10 CYTOKYNES IN THE PATHOGENIC MECHANISM OF THYROID CANCER.

, 2005
Thyroid cancer is cancer of the thyroid gland. These may be of many types including papillary, follicular, Hurthle cell (aka oxyphilic or oncocytic), or medullary cancers. Surgery plays an important role in treating these cancers.
TODARO M, STASSI, Giorgio, BONVENTRE, Sebastiano, TODARO, Matilde, MANNINO, Enzo   +4 more
core  

Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer [PDF]

, 2009
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the publication of the American Thyroid Association's guidelines for the management of these disorders was published in
Steward DL, Tuttle RM, Schlumberger M, Martin Schlumberger, Stephanie L. Lee, Haugen, Bryan R., McIver B, Cooper, David S., Haugen BR, Cooper DS, American Thyroid Association Guidelines Taskforce on Thyroid Nodules, Mandel, Susan J., Steward, David L., Bryan McIver, Richard T. Kloos, Mazzaferri EL, Steven I. Sherman, Doherty, Gerard M., Sherman, Steven I., Susan J. Mandel, Lee SL, Kloos RT, R. Michael Tuttle, McIver, Bryan, Ernest L. Mazzaferri, Kloos, Richard T., Lee, Stephanie L., Gerard M. Doherty, Pacini, Furio, Doherty GM, Bryan R. Haugen, Schlumberger, Martin, Furio Pacini, Differentiated Thyroid Cancer, David S. Cooper, Mazzaferri, Ernest L., Mandel SJ, Sherman SI, David L. Steward, Tuttle, R. Michael   +39 more
core   +1 more source

Genomic Alterations in Pulmonary Carcinoid Tumors: A Targeted Analysis of Gene Rearrangements and Oncogenic Mutations

Cancer Medicine, Volume 15, Issue 11, November 2026.
This study applied RNA‐based next‐generation sequencing to one of the largest cohorts of pulmonary carcinoid tumors analyzed to date and revealed rare yet potentially actionable gene rearrangements and variants, including alterations in ALK, BRAF, and EGFR.
Jenni Niinimäki, Soili Kytölä, Ari Ristimäki, Johanna Arola, Tiina Vesterinen   +4 more
wiley   +1 more source

Risk of thyroid cancer in relatives of patients with medullary thyroid carcinoma by age at diagnosis

, 2013
The familial risk of medullary thyroid carcinoma (MTC alone or as part of multiple endocrine neoplasms, MEN2A/MEN2B) is high, so we aimed to answer open questions about the lifetime cumulative risk of thyroid cancer (LCRTC at 0-79 years) among relatives ...
Sundquist, Kristina, Hemminki, Kari, Fallah, Mahdi, Hemminki, Kari,, Sundquist, Kristina,, Lund University.   +5 more
core   +2 more sources

Simultaneous Occurrence of Multicentric Medullary and Papillary Thyroid Cancer: A Case Report

, 2007
Background: Papillary thyroid cancer is a well-differentiated neoplasm and is the most common, accounting for 65?85% of all thyroid cancer. On the other hand, medullary carcinoma represents only 3?12%.
P. Castano, DIONIGI, GIANLORENZO, TANDA, MARIA LAURA PIERA, V. Bertolini, BARTALENA, LUIGI   +4 more
core   +1 more source

Uptodate view on diagnostics and treatment of medullary thyroid cancer

, 2013
During last 4 years leading endocrine societies of the world published clinical recommendations on diag nostics and treatment of medullary thyroid cancer.
D G Beltsevich, D O Gazizova
core   +1 more source

GLP‐1 Receptor Agonists Post‐Bariatric Surgery (GRABS) Trial: Rationale, Design and Baseline Characteristics

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9861-9870, November 2026.
ABSTRACT Aims No studies have investigated the synergistic effectiveness of Glucagon‐Like Peptide 1 Receptor Agonists (GLP1RAs) in patients with persistent obesity following bariatric surgery. The GLP‐1 Receptor Agonists Post‐Bariatric Surgery (GRABS) Trial aims to investigate the effectiveness of tirzepatide (TRZ) versus standard of care (SOC) after ...
J. M. Samuels, C. R. Williams, M. B. Patel, W. H. Self, L. M. Funk, C. Roumie, M. D. Spann, C. J. Northup, F. Ye, R. Irlmeier, I. Sohn, Y. Zhu, K. Niswender   +12 more
wiley   +1 more source