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Histopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends +48 more
wiley +1 more source
Kinase inhibitors in thyroid cancers
Endocrine OncologyObjective: The treatment landscape for thyroid cancers has changed rapidly with the availability of kinase inhibitors against VEGFR, BRAF, MEK, NTRK, and RET.
Vineeth Sukrithan +3 more
doaj +1 more source
The PI3K/Akt Pathway in Tumors of Endocrine Tissues [PDF]
, 2016 The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is a key driver in carcinogenesis. Defects in this pathway in human cancer syndromes such as Cowden’s disease and Multiple Endocrine Neoplasia result in tumors of endocrine tissues, highlighting its ...
Hague, Angela, Robbins, Helen Louise
core +2 more sources
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT This was the case of a 62‐year‐old patient treated with cabozantinib and nivolumab for metastatic clear cell renal cell carcinoma, in whom a clinically significant pharmacokinetic interaction with carbamazepine was observed. Carbamazepine, a potent inducer of CYP3A4, caused a major decrease in systemic exposure to cabozantinib, as confirmed by
Pierre Nizet +4 more
wiley +1 more source
CORRELATION OF FINE NEEDLE ASPIRATION AND FINAL HISTOPATHOLOGY IN THYROID DISEASE: A SERIES OF 702 PATIENTS MANAGED IN AN ENDOCRINE SURGICAL UNIT [PDF]
, 2012 Thyroid nodules are a common clinical entity found among the adult general population. With increasing use of imaging investigations like ultrasonography, there has been a significant rise in the detection of non-palpable thyroid nodules that require ...
Maharajan, Chandrasekaran +1 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Papillary carcinoma arising in a thyroglossal duct cyst is rare and often indistinguishable from benign disease. We report a male patient with progressive cyst changes leading to diagnosis and successful Sistrunk‐based management, highlighting the need for close, appropriate imaging and individualized treatment in midline neck masses.
Nasim Abukaresh +6 more
wiley +1 more source
Uncommon metastatic journey: unusual breast metastases of medullary thyroid carcinoma: a case report
BMC Women's HealthMedullary thyroid carcinoma is a neuroendocrine tumor derived from thyroid C-cells. It is a rare aggressive tumor, known to metastasize to lymph nodes, liver, bones, and lungs.
Saadallah Fatma +7 more
doaj +1 more source
Fine needle aspiration cytology of hepatic metastases of neuroendocrine tumors: A 20‐year retrospective, single institutional study [PDF]
, 2017 Background Fine needle aspiration (FNA) is considered an excellent technique for documenting metastatic neuroendocrine tumors (NETs). This study aims to evaluate the accuracy of FNA in diagnosing metastatic NETs to the liver and determining the grade ...
Cramer, Harvey +3 more
core +1 more source
Cancer Research, 2019 Highly penetrant hereditary thyroid cancer manifests as familial nonmedullary thyroid cancer (FNMTC), while low-penetrance hereditary thyroid cancer manifests as sporadic disease and is associated with common polymorphisms, including rs965513.
Darrin V Bann +9 more
semanticscholar +1 more source
Five Advances in the Last 50 Years That Have Impacted Endocrine Surgery
World Journal of Surgery, EarlyView.
Matilda Anneback +5 more
wiley +1 more source