Results 201 to 210 of about 34,058 (241)
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Journal of Surgical Oncology, 1975
AbstractMedullary thyroid carcinoma is an infrequent and unusual malignancy. Since its description 15 years ago, many new features have developed. Many biologically active compounds which are directly related to the different symptoms of the disease have been recovered from the tumors.
A C, Raynor, D, Sowden
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AbstractMedullary thyroid carcinoma is an infrequent and unusual malignancy. Since its description 15 years ago, many new features have developed. Many biologically active compounds which are directly related to the different symptoms of the disease have been recovered from the tumors.
A C, Raynor, D, Sowden
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Medullary Carcinoma of the Thyroid
Archives of Otolaryngology - Head and Neck Surgery, 1983Medullary cancer of the thyroid is rare but of unusual biologic interest. It originates in the thyroid parafollicular or C cells that are of neural crest origin and that secrete calcitonin. Calcitonin measurements, particularly after pentagastrim administration, are useful in detecting the tumor and following its progression.
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2011
Abstract Medullary thyroid carcinoma (MTC) is a rare calcitonin-secreting tumour of the parafollicular or C cells of the thyroid. As the C cells originate from the embryonic neural crest, MTC often have the clinical and histological features of neuroendocrine tumours.
Friedhelm Raue, Karin Frank-Raue
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Abstract Medullary thyroid carcinoma (MTC) is a rare calcitonin-secreting tumour of the parafollicular or C cells of the thyroid. As the C cells originate from the embryonic neural crest, MTC often have the clinical and histological features of neuroendocrine tumours.
Friedhelm Raue, Karin Frank-Raue
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Management of Medullary Thyroid Carcinoma
Endocrinology and Metabolism Clinics of North America, 2008Medullary thyroid carcinoma (MTC) is responsible for 13.4% of the total deaths attributable to thyroid cancer in human beings and research on MTC over the last 40 years has identified the RET proto-oncogene as a very relevant component of development of both sporadic and hereditary MTC. An activating germline RET proto-oncogene mutation responsible for
Camilo, Jiménez +2 more
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Canine Medullary Carcinoma of the Thyroid
Veterinary Pathology, 1978An 8-year-old male Irish Terrier dog and a male St. Bernard dog each had a thyroid medullary carcinoma. The first dog was hypocalcemic before removal and with recurrence of the neoplasm. In both dogs the neoplasms were bilateral and microscopic metastases were seen only in the regional lymph nodes.
A K, Patnaik +4 more
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Medullary Thyroid Carcinoma in Children
Seminars in Pediatric Surgery, 2020The vast majority of medullary thyroid carcinomas (MTC) in children are inherited as part of the multiple endocrine neoplasia (MEN) syndromes MEN2A and MEN2B, and the related variant, familial MTC. Prophylactic surgery in infants and children identified through genetic screening leads to the highest survival in these patients.
Claire E, Graves, Jessica E, Gosnell
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Medullary Carcinoma of the Thyroid
1990The results of our study may be summarized as follows: 1. Medullary carcinomas of the thyroid are derived from the C cells of the gland and are characterized by strong histologic and cytologic pleomorphism with inconstant stromal amyloid deposits. 2. The decisive morphodiagnostic criterion is immunohistochemical evidence of calcitonin coinciding with ...
W, Böcker, S, Schröder
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Cytogenetics of medullary carcinoma of the thyroid
Cancer Genetics and Cytogenetics, 1986Medullary carcinoma of the thyroid (MCT) is a dominantly inheritable neoplasm derived from intrathyroid C cells. The cytogenetics of this tumor has been only sparsely and indirectly studied previously. This article describes the chromosomes of primary MCT tumor tissue cultured with colcemid for 48 hr, metastatic tumor in lymph node cultured for 7 days ...
D H, Wurster-Hill +4 more
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Hyperthyroidism and Medullary Carcinoma of the Thyroid
Southern Medical Journal, 1980Unsuspected, medullary carcinoma of the thyroid was found on microscopic examination of thyroid tissue removed for treatment of hyperthyroidism in a 30-year-old woman. Preoperatively, the hyperthyroidism was attributed to Graves' disease, even though the patient had no pretibial myxedema or ophthalmic signs of Graves' disease.
K F, McFarland +2 more
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Medullary Thyroid Carcinoma in Children
2014Medullary thyroid carcinoma (MTC) originates from thyroid parafollicular C cells, and it accounts for 5% of thyroid malignancies. MTC is sporadic in approximately 80% and hereditary in 20% of cases. When hereditary it can be associated with other benign endocrine neoplasias and/or typical nonendocrine diseases, thus configuring the multiple endocrine ...
David Viola +2 more
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