Results 191 to 200 of about 34,058 (241)
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Current Opinion in Endocrinology, Diabetes & Obesity, 2021
Purpose of review To summarize recent developments in the diagnosis and management of patients with medullary thyroid cancer (MTC), with a focus on pathogenesis, systemic therapy, and future directions. Recent findings The addition of mutational analysis to cytological assessment of
Tania, Jaber, Ramona, Dadu, Mimi I, Hu
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Purpose of review To summarize recent developments in the diagnosis and management of patients with medullary thyroid cancer (MTC), with a focus on pathogenesis, systemic therapy, and future directions. Recent findings The addition of mutational analysis to cytological assessment of
Tania, Jaber, Ramona, Dadu, Mimi I, Hu
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Clinical Oncology, 2010
Medullary thyroid carcinoma (MTC) accounts for 5-8% of all thyroid cancers. MTC is mainly sporadic in nature, but an hereditary pattern [multiple endocrine neoplasia type 2 (MEN 2)] is present in 20-30% of cases, transmitted as an autosomal-dominant trait due to germline mutations of the RET proto-oncogene.
Pacini F. +3 more
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Medullary thyroid carcinoma (MTC) accounts for 5-8% of all thyroid cancers. MTC is mainly sporadic in nature, but an hereditary pattern [multiple endocrine neoplasia type 2 (MEN 2)] is present in 20-30% of cases, transmitted as an autosomal-dominant trait due to germline mutations of the RET proto-oncogene.
Pacini F. +3 more
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When is medullary thyroid carcinoma “medullary thyroid carcinoma”?
World Journal of Surgery, 1986AbstractMedullary thyroid carcinoma (MTC) is thought to develop from the parafollicular or C cells within the thyroid gland and, therefore, should not take up radioactive iodine. Recently, however,131I uptake has been reported in metastases of “medullary carcinoma” and, consequently, some authors have suggested that these tumors can be treated with ...
G, Riccabona, D, Ladurner, K, Schmid
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Medullary carcinoma of the thyroid
The Laryngoscope, 1976AbstractMedullary carcinoma is an unusual malignant neoplasm. The cell of origin is considered to be the C‐cell which is derived from the ultimo‐branchial body and neural crest. The tumor is solid and has characteristic amyloid in the stroma. The lesion usually presents as a neck mass, and multicentricity is not unusual.
Jeffrey Fierstein +3 more
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Endocrine Practice, 2013
This review outlines advances in the diagnosis, genetic testing, and progress in medullary thyroid cancer (MTC) treatment in light of the most recent evidence.English-language articles pertaining to MTC published up to 2012 were reviewed. The pertinent articles and their references were obtained and those considered relevant were reviewed for inclusion.
Marcio L, Griebeler +2 more
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This review outlines advances in the diagnosis, genetic testing, and progress in medullary thyroid cancer (MTC) treatment in light of the most recent evidence.English-language articles pertaining to MTC published up to 2012 were reviewed. The pertinent articles and their references were obtained and those considered relevant were reviewed for inclusion.
Marcio L, Griebeler +2 more
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Hematology/Oncology Clinics of North America, 2007
Medullary thyroid carcinoma is a neuroendocrine tumor derived from the C cells of the thyroid gland and accounts for approximately 5% of all thyroid carcinomas. Approximately 30% of the cases are associated with an autosomal dominant syndrome called multiple endocrine neoplasia type 2, and the identification of these individuals is important because ...
Ana O, Hoff, Paulo M, Hoff
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Medullary thyroid carcinoma is a neuroendocrine tumor derived from the C cells of the thyroid gland and accounts for approximately 5% of all thyroid carcinomas. Approximately 30% of the cases are associated with an autosomal dominant syndrome called multiple endocrine neoplasia type 2, and the identification of these individuals is important because ...
Ana O, Hoff, Paulo M, Hoff
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Medullary carcinoma of the thyroid
World Journal of Surgery, 1981AbstractMedullary carcinoma of the thyroid (MCT) is a rare tumor which, since its identification by Hazard et al. [2] in 1959, has attracted interest for 2 reasons. First, the secretion of the tumor marker, thyrocalcitonin, provides a means of making the diagnosis of MCT before the tumor is clinically evident.
J, Lynn, O I, Gamvros, S, Taylor
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Selective Ablation of Tumor Suppressors in Parafollicular C Cells Elicits Medullary Thyroid Carcinoma [PDF]
Journal of Biological Chemistry, 2017 Among the four different types of thyroid cancer, treatment of medullary thyroid carcinoma poses a major challenge because of its propensity of early metastasis.
Hai Song, Chuwen Lin, Erica Yao
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Current Treatment Options in Oncology, 2003
Medullary thyroid carcinoma (MTC) is a neuroendocrine malignancy that occurs in hereditary (25%) and sporadic (75%) clinical settings. MTC is present in all patients with the multiple endocrine neoplasia type 2 syndromes. MTCs produce calcitonin, the measurement of which can indicate the presence of tumors in people who are at risk and the ...
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Medullary thyroid carcinoma (MTC) is a neuroendocrine malignancy that occurs in hereditary (25%) and sporadic (75%) clinical settings. MTC is present in all patients with the multiple endocrine neoplasia type 2 syndromes. MTCs produce calcitonin, the measurement of which can indicate the presence of tumors in people who are at risk and the ...
openaire +2 more sources