Results 171 to 180 of about 30,437 (208)

Medullary Thyroid Carcinoma in Children

Seminars in Pediatric Surgery, 2020
The vast majority of medullary thyroid carcinomas (MTC) in children are inherited as part of the multiple endocrine neoplasia (MEN) syndromes MEN2A and MEN2B, and the related variant, familial MTC. Prophylactic surgery in infants and children identified through genetic screening leads to the highest survival in these patients.
Claire E, Graves, Jessica E, Gosnell
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Management of Medullary Thyroid Carcinoma

Endocrinology and Metabolism Clinics of North America, 2008
Medullary thyroid carcinoma (MTC) is responsible for 13.4% of the total deaths attributable to thyroid cancer in human beings and research on MTC over the last 40 years has identified the RET proto-oncogene as a very relevant component of development of both sporadic and hereditary MTC. An activating germline RET proto-oncogene mutation responsible for
Camilo, Jiménez, Mimi I-Nan, Hu, Robert F, Gagel   +2 more
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Canine Medullary Carcinoma of the Thyroid

Veterinary Pathology, 1978
An 8-year-old male Irish Terrier dog and a male St. Bernard dog each had a thyroid medullary carcinoma. The first dog was hypocalcemic before removal and with recurrence of the neoplasm. In both dogs the neoplasms were bilateral and microscopic metastases were seen only in the regional lymph nodes.
A K, Patnaik, P H, Lieberman, R A, Erlandson, W M, Acevedo, S K, Liu   +4 more
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Medullary Carcinoma of the Thyroid

1990
The results of our study may be summarized as follows: 1. Medullary carcinomas of the thyroid are derived from the C cells of the gland and are characterized by strong histologic and cytologic pleomorphism with inconstant stromal amyloid deposits. 2. The decisive morphodiagnostic criterion is immunohistochemical evidence of calcitonin coinciding with ...
W, Böcker, S, Schröder
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Medullary Thyroid Carcinoma in Children

2014
Medullary thyroid carcinoma (MTC) originates from thyroid parafollicular C cells, and it accounts for 5% of thyroid malignancies. MTC is sporadic in approximately 80% and hereditary in 20% of cases. When hereditary it can be associated with other benign endocrine neoplasias and/or typical nonendocrine diseases, thus configuring the multiple endocrine ...
VIOLA, DAVID, ROMEI, CRISTINA, ELISEI, ROSSELLA   +2 more
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Nonfamilial medullary thyroid carcinoma

The American Journal of Surgery, 1980
Abstract On the basis of this report and the current literature, we conclude that the familial type of medullary thyroid carcinoma can be diagnosed early using basal and poststimulation levels of calcitonin. However, most of the patients with sporadic disease present with a neck mass later in life.
R L, Rossi, B, Cady, W A, Meissner, M S, Wool, C E, Sedgwick, J, Werber   +5 more
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Cytogenetics of medullary carcinoma of the thyroid

Cancer Genetics and Cytogenetics, 1986
Medullary carcinoma of the thyroid (MCT) is a dominantly inheritable neoplasm derived from intrathyroid C cells. The cytogenetics of this tumor has been only sparsely and indirectly studied previously. This article describes the chromosomes of primary MCT tumor tissue cultured with colcemid for 48 hr, metastatic tumor in lymph node cultured for 7 days ...
D H, Wurster-Hill, W W, Noll, L Y, Bircher, O S, Pettengill, W A, Grizzle   +4 more
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Hyperthyroidism and Medullary Carcinoma of the Thyroid

Southern Medical Journal, 1980
Unsuspected, medullary carcinoma of the thyroid was found on microscopic examination of thyroid tissue removed for treatment of hyperthyroidism in a 30-year-old woman. Preoperatively, the hyperthyroidism was attributed to Graves' disease, even though the patient had no pretibial myxedema or ophthalmic signs of Graves' disease.
K F, McFarland, V C, Hawksley, J C, Reynolds   +2 more
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Histaminase and Medullary Thyroid Carcinoma

New England Journal of Medicine, 1970
The recognition of circulating gene products of tumor cells, and the development of sensitive methods for their detection in the serum of affected patients, is a potentially rewarding approach to the early diagnosis of cancer. Occurring probably as a result of genome derepression, these gene products frequently take the form of peptides or proteins ...
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FAMILIAL MEDULLARY THYROID CARCINOMA

The Lancet, 1978
Medullary thyroid carcinoma (M.C.T.) is a tumour of the calcitonin-secreting cells of the thyroid gland; it affects both lobes, has a variable malignant potential, and is often familial. Despite the availability of diagnostic plasma-calcitonin immunoassays, the condition is rarely considered in the initial assessment of a patient with a thyroid mass so
C J, Hillyard, I M, Evans, P A, Hill, S, Taylor   +3 more
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