Results 161 to 170 of about 30,437 (208)
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Clinical Oncology, 2010
Medullary thyroid carcinoma (MTC) accounts for 5-8% of all thyroid cancers. MTC is mainly sporadic in nature, but an hereditary pattern [multiple endocrine neoplasia type 2 (MEN 2)] is present in 20-30% of cases, transmitted as an autosomal-dominant trait due to germline mutations of the RET proto-oncogene.
Pacini F. +3 more
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Medullary thyroid carcinoma (MTC) accounts for 5-8% of all thyroid cancers. MTC is mainly sporadic in nature, but an hereditary pattern [multiple endocrine neoplasia type 2 (MEN 2)] is present in 20-30% of cases, transmitted as an autosomal-dominant trait due to germline mutations of the RET proto-oncogene.
Pacini F. +3 more
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When is medullary thyroid carcinoma “medullary thyroid carcinoma”?
World Journal of Surgery, 1986AbstractMedullary thyroid carcinoma (MTC) is thought to develop from the parafollicular or C cells within the thyroid gland and, therefore, should not take up radioactive iodine. Recently, however,131I uptake has been reported in metastases of “medullary carcinoma” and, consequently, some authors have suggested that these tumors can be treated with ...
G, Riccabona, D, Ladurner, K, Schmid
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Medullary carcinoma of the thyroid
The Laryngoscope, 1976AbstractMedullary carcinoma is an unusual malignant neoplasm. The cell of origin is considered to be the C‐cell which is derived from the ultimo‐branchial body and neural crest. The tumor is solid and has characteristic amyloid in the stroma. The lesion usually presents as a neck mass, and multicentricity is not unusual.
Jeffrey Fierstein +3 more
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Hematology/Oncology Clinics of North America, 2007
Medullary thyroid carcinoma is a neuroendocrine tumor derived from the C cells of the thyroid gland and accounts for approximately 5% of all thyroid carcinomas. Approximately 30% of the cases are associated with an autosomal dominant syndrome called multiple endocrine neoplasia type 2, and the identification of these individuals is important because ...
Ana O, Hoff, Paulo M, Hoff
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Medullary thyroid carcinoma is a neuroendocrine tumor derived from the C cells of the thyroid gland and accounts for approximately 5% of all thyroid carcinomas. Approximately 30% of the cases are associated with an autosomal dominant syndrome called multiple endocrine neoplasia type 2, and the identification of these individuals is important because ...
Ana O, Hoff, Paulo M, Hoff
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Endocrine Practice, 2013
This review outlines advances in the diagnosis, genetic testing, and progress in medullary thyroid cancer (MTC) treatment in light of the most recent evidence.English-language articles pertaining to MTC published up to 2012 were reviewed. The pertinent articles and their references were obtained and those considered relevant were reviewed for inclusion.
Marcio L, Griebeler +2 more
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This review outlines advances in the diagnosis, genetic testing, and progress in medullary thyroid cancer (MTC) treatment in light of the most recent evidence.English-language articles pertaining to MTC published up to 2012 were reviewed. The pertinent articles and their references were obtained and those considered relevant were reviewed for inclusion.
Marcio L, Griebeler +2 more
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Medullary carcinoma of the thyroid
World Journal of Surgery, 1981AbstractMedullary carcinoma of the thyroid (MCT) is a rare tumor which, since its identification by Hazard et al. [2] in 1959, has attracted interest for 2 reasons. First, the secretion of the tumor marker, thyrocalcitonin, provides a means of making the diagnosis of MCT before the tumor is clinically evident.
J, Lynn, O I, Gamvros, S, Taylor
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Current Treatment Options in Oncology, 2003
Medullary thyroid carcinoma (MTC) is a neuroendocrine malignancy that occurs in hereditary (25%) and sporadic (75%) clinical settings. MTC is present in all patients with the multiple endocrine neoplasia type 2 syndromes. MTCs produce calcitonin, the measurement of which can indicate the presence of tumors in people who are at risk and the ...
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Medullary thyroid carcinoma (MTC) is a neuroendocrine malignancy that occurs in hereditary (25%) and sporadic (75%) clinical settings. MTC is present in all patients with the multiple endocrine neoplasia type 2 syndromes. MTCs produce calcitonin, the measurement of which can indicate the presence of tumors in people who are at risk and the ...
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2011
Abstract Medullary thyroid carcinoma (MTC) is a rare calcitonin-secreting tumour of the parafollicular or C cells of the thyroid. As the C cells originate from the embryonic neural crest, MTC often have the clinical and histological features of neuroendocrine tumours.
Friedhelm Raue, Karin Frank-Raue
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Abstract Medullary thyroid carcinoma (MTC) is a rare calcitonin-secreting tumour of the parafollicular or C cells of the thyroid. As the C cells originate from the embryonic neural crest, MTC often have the clinical and histological features of neuroendocrine tumours.
Friedhelm Raue, Karin Frank-Raue
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Journal of Surgical Oncology, 1975
AbstractMedullary thyroid carcinoma is an infrequent and unusual malignancy. Since its description 15 years ago, many new features have developed. Many biologically active compounds which are directly related to the different symptoms of the disease have been recovered from the tumors.
A C, Raynor, D, Sowden
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AbstractMedullary thyroid carcinoma is an infrequent and unusual malignancy. Since its description 15 years ago, many new features have developed. Many biologically active compounds which are directly related to the different symptoms of the disease have been recovered from the tumors.
A C, Raynor, D, Sowden
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Medullary Carcinoma of the Thyroid
Archives of Otolaryngology - Head and Neck Surgery, 1983Medullary cancer of the thyroid is rare but of unusual biologic interest. It originates in the thyroid parafollicular or C cells that are of neural crest origin and that secrete calcitonin. Calcitonin measurements, particularly after pentagastrim administration, are useful in detecting the tumor and following its progression.
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