Results 211 to 220 of about 34,058 (241)

Nonfamilial medullary thyroid carcinoma

The American Journal of Surgery, 1980
Abstract On the basis of this report and the current literature, we conclude that the familial type of medullary thyroid carcinoma can be diagnosed early using basal and poststimulation levels of calcitonin. However, most of the patients with sporadic disease present with a neck mass later in life.
R L, Rossi, B, Cady, W A, Meissner, M S, Wool, C E, Sedgwick, J, Werber   +5 more
openaire   +2 more sources

Histaminase and Medullary Thyroid Carcinoma

New England Journal of Medicine, 1970
The recognition of circulating gene products of tumor cells, and the development of sensitive methods for their detection in the serum of affected patients, is a potentially rewarding approach to the early diagnosis of cancer. Occurring probably as a result of genome derepression, these gene products frequently take the form of peptides or proteins ...
openaire   +2 more sources

Management of medullary carcinoma of the thyroid

The American Journal of Surgery, 1982
Total thyroidectomy is universally advised for the familial variety of MCT. Although total thyroidectomy is also recommended for sporadic cases, partial thyroidectomy may be adequate. Cervical and upper mediastinal nodes should be sampled for microscopic study, even when they are small and appear to be normal.
W J, Simpson, J A, Palmer, I B, Rosen, R A, Mustard   +3 more
openaire   +2 more sources

FAMILIAL MEDULLARY THYROID CARCINOMA

The Lancet, 1978
Medullary thyroid carcinoma (M.C.T.) is a tumour of the calcitonin-secreting cells of the thyroid gland; it affects both lobes, has a variable malignant potential, and is often familial. Despite the availability of diagnostic plasma-calcitonin immunoassays, the condition is rarely considered in the initial assessment of a patient with a thyroid mass so
C J, Hillyard, I M, Evans, P A, Hill, S, Taylor   +3 more
openaire   +2 more sources

Mucosubstances in medullary carcinoma of the thyroid

Histopathology, 1988
We have studied mucosubstances in 12 cases of medullary carcinoma of the thyroid using histochemical techniques and a number of different lectins. Immunohistochemical staining for calcitonin and carcinoembryonic antigen was also performed. We have found that the presence of mucosubstances is a constant finding in medullary carcinomas; they were present
I, Martin-Lacave, R, Gonzalez-Campora, A, Moreno Fernandez, F, Sachez Gallego, C, Montero, H, Galera-Davidson   +5 more
openaire   +2 more sources

Medullary Carcinoma of the Thyroid Gland

World Journal of Surgery, 2000
AbstractMedullary thyroid carcinoma (MTC) is an uncommon thyroid tumor that has attracted a great deal of interest because of its frequent presentation as a familial tumor and its primary involvement in the type II multiple endocrine neoplasia (MEN) syndromes MEN‐IIA and MEN‐IIB and familial medullary thyroid carcinoma (FMTC).
S A, Wells, C, Franz
openaire   +2 more sources

Medullary carcinoma of the thyroid gland

The Laryngoscope, 1976
AbstractEndocrine as well as oncologic attributes mark this rare tumor as unique. It is derived from “C cells” resembling the parafollicular cells of lower animals; these cells elaborate Calcitonin which acts as a sensitive signal of the presence of the tumor.
openaire   +3 more sources

Hypouricemia and Medullary Carcinoma of the Thyroid

1984
Hypouricemia could be the result of diminished uric acid production, excess urate excretion, or a combination of these mechanisms. Recently, hypouricemia has been noted in a few patients with neoplastic diseases, particularly Hodgkin’s disease and pulmonary tumors1.
J G, Puig, A F, Mateos, G, Gaspar, E M, Martinez, T, Ramos, A, Lesmes   +5 more
openaire   +2 more sources

Epidemiology of Medullary Thyroid Carcinoma

1992
Medullary thyroid carcinoma (MTC) was first recognized as a distinct pathological entity by Hazard et al. (1959), who, out of 600 cases of thyroid cancer, identified 21 cases of this tumor from its histopathological appearance. MTC originates from the thyroid parafollicular C-cells first suggested by Williams (1967) and secretes large amounts of ...
openaire   +2 more sources

[Medullary carcinoma of thyroid gland].

Chirurgia italiana, 1997
The authors present the characteristic features of medullary carcinoma of thyroid (CMT) and underline the necessity to identify RET proto-oncogene that is the cause of hereditary transmission of CMT. Physiology of C cells and clinical syndromes are reported and the importance of a genetic screening in population at risk is emphasized; this test has ...
SPINELLI, CLAUDIO, Galleri D, Calbo L, Palmeri R, MICCOLI, PAOLO, Melita P.   +5 more
openaire   +2 more sources