Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
A detailed analysis of the hybrid lattice-reduction and meet-in-the-middle attack
Over the past decade, the hybrid lattice-reduction and meet-in-the middle attack (called hybrid attack) has been used to evaluate the security of many lattice-based cryptographic schemes such as NTRU, NTRU Prime, BLISS and more.
Wunderer Thomas
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Improved preimage and pseudo-collision attacks on SM3 hash function
A preimage attack on 32-step SM3 hash function and a pseudo-collision attack on 33-step SM3 hash function respectively were shown.32-step preimage attack was based on the differential meet-in-the-middle and biclique technique,while the previously known ...
Jian ZOU, Le DONG
doaj +2 more sources
A Known-Plaintext Attack with Minimal Data Complexity on 25-Round CRAFT
We present the first known-plaintext attack on up to 25 rounds of the tweakable block cipher Craft. These attacks require only two known plaintextciphertext pairs to recover the full key, and work independent of the used tweaks.
Eran Lambooij, Patrick Neumann
doaj +1 more source
Improved Meet-in-the-Middle Preimage Attacks against AES Hashing Modes
Hashing modes are ways to convert a block cipher into a hash function, and those with AES as the underlying block cipher are referred to as AES hashing modes.
Zhenzhen Bao +4 more
doaj +1 more source
Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen +11 more
wiley +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Collision Attacks on AES-192/256, Crypton-192/256, mCrypton-96/128, and Anubis
At AES’00, a collision attack on 7-round reduced AES was proposed. In this paper, we apply this idea to seven SPN block ciphers, AES-192/256, Crypton-192/256, mCrypton-96/128, and Anubis.
Jinkeon Kang +4 more
doaj +1 more source

