Results 51 to 60 of about 34,772 (247)

"Low-Positive" MOG-IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Villacieros-Álvarez J, Espejo C, Arrambide G, Castillo M, Rodriguez M, Ariño H, Elosua I, Tur C, Vidal-Jordana A, Vilaseca A, Castilló J, Galán I, Midaglia L, Nos C, Rodríguez-Acevedo B, Zabalza A, Bollo L, Pappolla A, Carvajal R, Mongay-Ochoa N, Rio J, Sastre-Garriga J, Comabella M, Busiello G, Sceppacuercia S, Rovira À, Montalban X, Tintoré M, Auger C, Cobo-Calvo Á.   +29 more
europepmc   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impossible Differential Cryptanalysis of SIMECK32/64 Algorithm [PDF]

Jisuanji gongcheng, 2017
This paper studies the capability of impossible differential cryptanalysis on block cipher SIMECK32/64.The 11-round impossible differential path of SIMECK32/64 is constructed using the meet-in-the-middle technology.The attack on 19-round SIMECK32/64 is ...
CHEN Yanqin,ZHANG Wenying
doaj   +1 more source

Improved Meet-in-the-Middle Attacks on Reduced-Round DES [PDF]

, 2007
The Data Encryption Standard (DES) is a 64-bit block cipher. Despite its short key size of 56 bits, DES continues to be used to protect financial transactions valued at billions of Euros. In this paper, we investigate the strength of DES against attacks that use a limited number of plaintexts and ciphertexts.
Dunkelman, Orr, Sekar, Gautham, Preneel, Bart   +2 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Hybrid of Dual and Meet-in-the-Middle Attack on Sparse and Ternary Secret LWE

IEEE Access, 2019
The dual attack is one of the most efficient attack algorithms for learning with errors (LWE) problem. Recently, an efficient variant of the dual attack for sparse and small secret LWE was reported by Albrecht (Eurocrypt 2017), which forces some LWE ...
Jung Hee Cheon, Minki Hhan, Seungwan Hong, Yongha Son   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source