Results 71 to 80 of about 306,267 (282)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Impossible Differential Cryptanalysis of SIMECK32/64 Algorithm [PDF]

Jisuanji gongcheng, 2017
This paper studies the capability of impossible differential cryptanalysis on block cipher SIMECK32/64.The 11-round impossible differential path of SIMECK32/64 is constructed using the meet-in-the-middle technology.The attack on 19-round SIMECK32/64 is ...
CHEN Yanqin,ZHANG Wenying
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Improving Implementable Meet-in-the-Middle Attacks by Orders of Magnitude [PDF]

, 1996
Meet-in-the-middle attacks, where problems and the secrets being sought are decomposed into two pieces, have many applications in cryptanalysis. A well-known such attack on double-DES requires 256 time and memory; a naive key search would take 2112 time.
Paul C. van Oorschot, Michael J. Wiener
openaire   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Improved Meet-in-the-Middle Attacks on Reduced-Round DES [PDF]

, 2007
The Data Encryption Standard (DES) is a 64-bit block cipher. Despite its short key size of 56 bits, DES continues to be used to protect financial transactions valued at billions of Euros. In this paper, we investigate the strength of DES against attacks that use a limited number of plaintexts and ciphertexts.
Dunkelman, Orr, Sekar, Gautham, Preneel, Bart   +2 more
openaire   +2 more sources

Improved preimage and pseudo-collision attacks on SM3 hash function

Tongxin xuebao, 2018
A preimage attack on 32-step SM3 hash function and a pseudo-collision attack on 33-step SM3 hash function respectively were shown.32-step preimage attack was based on the differential meet-in-the-middle and biclique technique,while the previously known ...
Jian ZOU, Le DONG
doaj   +2 more sources

A Known-Plaintext Attack with Minimal Data Complexity on 25-Round CRAFT

IACR Transactions on Symmetric Cryptology
We present the first known-plaintext attack on up to 25 rounds of the tweakable block cipher Craft. These attacks require only two known plaintextciphertext pairs to recover the full key, and work independent of the used tweaks.
Eran Lambooij, Patrick Neumann
doaj   +1 more source