Results 111 to 120 of about 646,929 (245)

Expert meeting report: epidemiology and management of acquired hypothalamic obesity. [PDF]

Front Endocrinol (Lausanne)
Müller HL, Bartels UK, Denzer C, Dischinger U, Flitsch J, Gojo J, Richter-Unruh A, Scheinemann K, Schilbach K, Friedrich C.   +9 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Meeting Report: Fourth Correlates of Protection for Next Generation Influenza Vaccines. [PDF]

Influenza Other Respir Viruses
Tscherne A, Cox RJ, Krammer F, Bonnevie A.   +3 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Advancing diagnostics for Chagas disease: key product characteristics and harmonized evaluation strategies - an expert meeting report. [PDF]

BMC Infect Dis
Bohorquez LC, Schijman AG, Perez F, Coto H, Marchiol A, Pinazo MJ.   +5 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Dissemination of EFFORT trial results in Indonesia: a stakeholder meeting report on tafenoquine and primaquine for radical cure of Plasmodium vivax. [PDF]

Malar J
Pasaribu AP, Jimanto V, Ainur F, Saragih NR, Hadi H, Siagian DSP, Sinaga BJ, Satyagraha AW, Laihad FJ, Diptyanusa A, Ubra RR, Tekege O, Darmayanti L, Herdiana H, Adella J, Mannion K, Curry E, Poespoprodjo JR, Kenangalem E, Burdam FH, Sutanto I, Nelwan EJ, Ganadhi GJ, Shrestha B, Mnjala H, Hawley WA, Prameswari HD, Theodora M, Silalahi FSM, Susanto H, Immanuella F, Puspadewi RT, Fajariyani SB, Samad I, Supriyanto D, Muhafilah N, Isa R, Price RN, Thriemer K.   +38 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Accelerating HPV-related cancer elimination - a meeting report. [PDF]

BMC Proc
Burdier FR, Bosch FX, Waheed DE, Teblick L, Poljak M, Baay M, de Sanjosé S, Bardou M, Baussano I, Man I, Franco EL, Vorsters A.   +11 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source