Results 1 to 10 of about 4,982 (197)

Exploring the Conformational Equilibrium of Mefenamic Acid Released from Silica Aerogels via NMR Analysis [PDF]

International Journal of Molecular Sciences, 2023
This study examines the influence of mefenamic acid on the physical and chemical properties of silica aerogels, as well as its effect on the sorption characteristics of the composite material.
Ilya A Khodov, Valentina V Sobornova, Konstantin V Belov   +2 more
exaly   +3 more sources

Enhancing the dissolution rate of mefenamic acid with solid dispersion system using avicel PH-101 [PDF]

Pharmaciana, 2019
Mefenamic acid, based on the Biopharmaceutics Classification System (BCS), is a class II drug that has high permeability but low water solubility. To improve its intrinsic dissolution rate, it is usually combined with a hydrophilic and porous drug ...
Widyasari Putranti, Lina Widiyastuti, Fitri Ulfani   +2 more
doaj   +3 more sources

Graded activation of mutant K41C-KCNE1:KCNQ1 channel complexes by mefenamic acid [PDF]

Channels
The IKs current formed by the co-assembly of KCNE1 and KCNQ1 plays an important role in cardiac repolarization. Mefenamic acid, an NSAID, is known to enhance IKs currents and has in turn been suggested as a therapeutic starting point for the development ...
Yundi Wang, Magnus Chan, Marc Pourrier, Jodene Eldstrom, David Fedida   +4 more
doaj   +2 more sources

Treatment of Epidermal Pathology in a Pediatric Patient With Keratitis-Ichthyosis-Deafness (KID) Syndrome With Topical Mefenamic Acid. [PDF]

Pediatr Dermatol
ABSTRACT Keratitis–ichthyosis–deafness (KID) syndrome is a rare genetic condition typically presenting at birth with ichthyosiform erythroderma and bilateral hearing loss and later progressing to diffuse keratodermatous plaques with scaling. The condition is associated with mutations in the GJB2 gene, which lead to aberrant activation of connexin ...
Gupta R, Ho A, Brichta L, Yan AC.
europepmc   +2 more sources

Efficacy of Plant-Derived Therapies for Primary Dysmenorrhea: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Phytother Res
ABSTRACT Primary dysmenorrhea is defined as recurrent, cramp‐like lower abdominal pain occurring during menstruation in the absence of underlying pelvic pathology. A significant proportion of the population opts for natural plant‐based remedies due to their perceived lower incidence of adverse effects.
Wu L, Xu Lou I, Hu Z, Wang G, Deshpande SV, Cáceres-Matos R.   +5 more
europepmc   +2 more sources

Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasisResearch in context [PDF]

EBioMedicine, 2019
Background: Treatment and control of schistosomiasis, one of the most insidious and serious parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding for drug development for poverty-associated diseases is very limited,
Eloi M. Lago, Marcos P. Silva, Talita G. Queiroz, Susana F. Mazloum, Vinícius C. Rodrigues, Paulo U. Carnaúba, Pedro L. Pinto, Jefferson A. Rocha, Leonardo L.G. Ferreira, Adriano D. Andricopulo, Josué de Moraes   +10 more
doaj   +2 more sources

Comparison of Misoprostol and Mefenamic Acid on Reducing Menstrual Bleeding in Patients Suffering From Heavy Menstrual Bleeding [PDF]

Journal of Family and Reproductive Health, 2019
Objective: Heavy menstrual bleeding is one of the most frequent complaints of women. Various therapeutic approaches have been applied to treat this condition.
Tahereh Eftekhar, Marjan Ghaemi, Aref Abedi, Mahboobeh Shirazi   +3 more
doaj   +2 more sources

A new self-emulsifying formulation of mefenamic acid with enhanced drug dissolution

Asian Journal of Pharmaceutical Sciences, 2015
To enhance the dissolution of poorly soluble mefenamic acid, self-emulsifying formulation (SEF), composing of oil, surfactant and co-surfactant, was formulated.
Pornsak Sriamornsak, Sontaya Limmatvapirat, Suchada Piriyaprasarth, Punyanutch Mansukmanee, Zongkang Huang   +4 more
doaj   +3 more sources

Ethanolic extract of Lannea coromandelica stem bark: Histopathology and infiltration of inflammatory cells in the rat's gastric

Journal of Advanced Pharmaceutical Technology & Research, 2022
This study determined the efficacy of extract of the stem bark of Lannea coromandelica (ESBLc) on histopathology and inflammatory cell infiltration in the gastric of rats induced by mefenamic acid.
Achmad Ramadhan, Hastuti Herman, Sutrisnawati Sutrisnawati   +2 more
doaj   +1 more source

Comparing the Effect of Ginger-Lavender, Ginger and Mefenamic Acid Capsules on the Severity of Primary Dysmenorrhea among University Students: A Triple-Blind Clinical Trial [PDF]

Journal of Midwifery & Reproductive Health, 2023
Background & aim: Primary dysmenorrhea is one of the most common complaints in women. This study compared the effect of ginger-lavender, ginger and mefenamic acid capsules on the severity of primary dysmenorrhea among female university students.Methods ...
Shadi Ahmadi, Sharareh Jannesari, Malihe Nasiri, Shamim Sahranavard   +3 more
doaj   +1 more source