Graded activation of mutant K41C-KCNE1:KCNQ1 channel complexes by mefenamic acid [PDF]
ChannelsThe IKs current formed by the co-assembly of KCNE1 and KCNQ1 plays an important role in cardiac repolarization. Mefenamic acid, an NSAID, is known to enhance IKs currents and has in turn been suggested as a therapeutic starting point for the development ...
Yundi Wang +4 more
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Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasisResearch in context [PDF]
EBioMedicine, 2019 Background: Treatment and control of schistosomiasis, one of the most insidious and serious parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding for drug development for poverty-associated diseases is very limited,
Eloi M. Lago +10 more
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Comparison of Misoprostol and Mefenamic Acid on Reducing Menstrual Bleeding in Patients Suffering From Heavy Menstrual Bleeding [PDF]
Journal of Family and Reproductive Health, 2019 Objective: Heavy menstrual bleeding is one of the most frequent complaints of women. Various therapeutic approaches have been applied to treat this condition.
Tahereh Eftekhar +3 more
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A new self-emulsifying formulation of mefenamic acid with enhanced drug dissolution
Asian Journal of Pharmaceutical Sciences, 2015 To enhance the dissolution of poorly soluble mefenamic acid, self-emulsifying formulation (SEF), composing of oil, surfactant and co-surfactant, was formulated.
Pornsak Sriamornsak +4 more
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Journal of Advanced Pharmaceutical Technology & Research, 2022 This study determined the efficacy of extract of the stem bark of Lannea coromandelica (ESBLc) on histopathology and inflammatory cell infiltration in the gastric of rats induced by mefenamic acid.
Achmad Ramadhan +2 more
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Comparing the Effect of Ginger-Lavender, Ginger and Mefenamic Acid Capsules on the Severity of Primary Dysmenorrhea among University Students: A Triple-Blind Clinical Trial [PDF]
Journal of Midwifery & Reproductive Health, 2023 Background & aim: Primary dysmenorrhea is one of the most common complaints in women. This study compared the effect of ginger-lavender, ginger and mefenamic acid capsules on the severity of primary dysmenorrhea among female university students.Methods ...
Shadi Ahmadi +3 more
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Removal of Mefenamic Acid from Aqueous Solution by Fenton Process: Optimization Using Response Surface Methodology with Central Composite Design [PDF]
Nature Environment and Pollution Technology, 2021 In the present study, the three main process parameters in the Fenton process for the removal of pharmaceutical compound Mefenamic acid from an aqueous solution were optimized using response surface methodology (RSM).
R. Deepa, G. Madhu, Roy M Thomas and V. Sivanandan Achari
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Enhancing the dissolution rate of mefenamic acid with solid dispersion system using avicel PH-101 [PDF]
Pharmaciana, 2019 Mefenamic acid, based on the Biopharmaceutics Classification System (BCS), is a class II drug that has high permeability but low water solubility. To improve its intrinsic dissolution rate, it is usually combined with a hydrophilic and porous drug ...
Widyasari Putranti +2 more
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The Journal of Headache and Pain, 2022 Background/aim Certain constituents in migraine food triggers and non-steroidal anti-inflammatory drugs (NSAIDs) inhibit sulfotransferases (SULTs) that detoxify drugs/chemicals and play role in the metabolism of neurotransmitters.
Doga Vuralli +6 more
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Effects of the Combination of Nigella Sativa and Mefenamic Acid and Mefenamic Acid Alone on the Severity of Postpartum Pain in Multiparous Women: A Double-Blind Clinical Trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2018 Introduction: Postpartum pain or painful uterine contractions is an important postpartum problem, and its relief could improve breastfeeding and mother-infant interactions.
Maryam Chananeh +4 more
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