Results 31 to 40 of about 3,678 (166)

Induction of cytochrome P450 2C9 and P‐glycoprotein activity by antiseizure medications: A systematic review and network meta‐analysis

Epileptic Disorders, Volume 28, Issue 3, Page 855-867, June 2026.
Abstract Objectives Antiseizure medications (ASMs) can induce the activity of drug‐metabolizing enzymes and drug transporters, including cytochrome P450 (CYP)2C9 and P‐glycoprotein (P‐gp). Our objective was to comparatively assess the effects of ASMs on exposure to clinical CYP2C9 and P‐gp substrates.
Hagar Cohen, Nahawand Bahash, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

Prevalence of Dysmenorrhea and Its Association With Dietary Habits Among Female Students of Mid‐West University, Surkhet, Nepal: An Analytical Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Dysmenorrhea is a common gynecological condition affecting young women and is associated with reduced academic performance and quality of life. This study aimed to determine the prevalence of dysmenorrhea and examine its association with dietary habits among female students at Mid‐West University, Surkhet, Nepal. Methods An
Rashmi Pant, Mamta Verma, Rima Mishra, Ganesh Bhandari   +3 more
wiley   +1 more source

Evaluation of mint efficacy regarding dysmenorrhea in comparison with mefenamic acid: A double blinded randomized crossover study

Iranian Journal of Nursing and Midwifery Research, 2016
Background: Menthol is the most important active material in mint and different mechanisms have been suggested for the way mint functions, most of which emphasize its analgesic effect owing to the presence of a group of temporary protein receptors.
Seyedeh Zahra Masoumi, Horieh Rezvani Asl, Jalal Poorolajal, Mohammad Hosseini Panah, Seyedeh Reyhaneh Oliaei   +4 more
doaj   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Wound‐Healing Efficacy of Garcinia pedunculata Fruit Extract: In Vivo and In Silico Validation of Regenerative Mechanisms With Histological Analysis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
This study demonstrates that G. pedunculata fruit possesses potent wound‐healing activity, evidenced by accelerated wound contraction, reduced epithelialization time, enhanced fibroblast proliferation, increased collagen deposition, and improved neovascularization in both excision and burn models. ABSTRACT Garcinia pedunculata Roxb., traditionally used
Kazi Sanjida Tahrim, Md. Mushfiqur Rahman, Md. Sohanur Rahman, Mohammad Abu Sayem, Md. Safayat Hossen Momen, Tanvir Hasan, Md. Jahirul Islam Mamun, Md. Mahmudul Hasan   +7 more
wiley   +1 more source

The Application of Metal–Organic Frameworks as Drug Delivery Systems: From the Perspective of Molecular Dynamics Simulations

MedComm, Volume 7, Issue 4, April 2026.
This review article provides a comprehensive exploration of the synergistic integration of molecular dynamics (MD) simulations and metal–organic frameworks (MOFs) to advance the design and optimization of nanoscale drug delivery systems (DDSs). We believe this work will be of significant interest to researchers in nanomedicine, computational biology ...
Jiahao Xu, Hanzi Zheng, Yue Gao, Yuanqiu Lai, Mengya Peng, Yike Hu, Tianmeng Yuan, Xiang Liu, Shihan Zhou, Wei Duan, Jia‐Wei Shen, Yongke Zheng   +11 more
wiley   +1 more source

In Silico Coformer Screening for Mefenamic Acid Cocrystallization

Jurnal Info Kesehatan
Cocrystallization is a widely used approach to enhance the solubility and dissolution characteristics of poorly soluble drugs. A pharmaceutical cocrystal is a multicomponent system composed of a solid active pharmaceutical ingredient (API) and a coformer,
Aulia Fikri Hidayat, Taufik Muhammad Fakih, Gita Cahya Eka Darma, Ratu Choesrina   +3 more
doaj   +1 more source

Histopathology, Diagnosis, Management and Treatment Outcomes of Cemental Tears: A Retrospective Observational Cohort Study

International Endodontic Journal, Volume 59, Issue 4, Page 614-631, April 2026.
ABSTRACT Introduction Diagnosing cemental tears remains challenging, and treatment outcomes can be unpredictable; recommendations for their diagnosis and management are primarily based on case reports and anecdotal experience. Although a classification has been developed for cemental tears, its clinical applicability and importance have yet to be ...
Angeline Hui Cheng Lee, Mei Zhi Ting, May Chun Mei Wong, Chengfei Zhang   +3 more
wiley   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, Volume 21, Issue 2, March/April 2026.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

The Effect Of Mefenamic Acid On Longitudinal Development Of Growth Plate In Young Male White Rats

Journal of Agromedicine and Medical Sciences (AMS), 2016
The past epidemiologic studies did not have definite explanation about the effect of consuming Mefenamic Acid on Longitudinal Bone Development. The aim of this study is to explain the effect of Mefenamic Acid on Longitudinal Bone Development.
Muhamad Hasan
doaj