Results 51 to 60 of about 4,982 (197)
ABSTRACT Ecopipam, a selective dopamine D1 receptor antagonist in development for Tourette syndrome, is primarily converted by uridine diphosphate‐glucuronosyltransferase (UGT)1A9 to ecopipam glucuronide, with a minor metabolic pathway by cytochrome P450 3A4 forming EBS‐101‐40853 (also referred to as N‐desmethylecopipam or SCH 40853; also ...
Virginia D. Schmith +3 more
wiley +1 more source
Crystallization of mefenamic acid and polymorphs
The crystallization of Mefenamic Acid, (MA), which has a prevalent usage in drug formulation, was investigated. MA is a high-dose, anti-inflammatory, analgesic agent used for pain in menstrual disorders.
Gokbel S., Cesur S.
core +1 more source
Nanoparticle based technologies improve the efficiency and speed of already existing processes.The larger size materials and reagents which are in reactive form, can be nanosized to give efficient output.
Vedavahini, Parankusham, Sailu, Chintha
core +1 more source
This work reviews recent advances in Organic Semiconducting Single Crystals (OSSCs), focusing on mechanical flexibility for robust devices, polymorph control for precise phase selection, and interface engineering with self‐assembled monolayers to improve alignment and performance.
Alessando Fraleoni‐Morgera +3 more
wiley +1 more source
Novel colorimetric assay of mefenamic acid using 4-amino-3,5-dinitrobenzoic acid (ADBA)
Purpose: To develop a novel colorimetric assay method for mefenamic acid capsules. Method: The new method (aromatic ring derivatization technique) is based on a diazo coupling reaction using diazotized 4-amino-3,5-dinitrobenzoic acid (ADBA) as a ...
Idowu, SO +7 more
core +1 more source
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik +7 more
wiley +1 more source
A highly sensitive electrochemical sensor featuring lanthanum stannate nanomaterial is introduced for the rapid detection of bisphenol A (BPA) in water. The sensor delivers fast response, excellent selectivity, and ultra‐low detection limits, enabling reliable monitoring of BPA in real environmental samples.
Ragu Sasikumar +4 more
wiley +1 more source
An investigation of the neuropharmacological and behavioural effects of fenamate and other NSAIDs. [PDF]
Recent evidence has indicated that NSAIDs might have direct effects on CNS tissue in addition to their classical inhibitory action on COX enzymes. This thesis addresses this hypothesis using electrophysiological and behavioural techniques. The effects of
Foxon, Graham Ronald
core
Objectives: Mefenamic acid is used as a modal nonsteroidal anti-inflammatory drug for analytical estimation. Due to the poor aqueous solubility, mefenamic acid liberated reduced bioavailability.
TRIPATHI, DEVIKA +2 more
core
Safety of tolfenamic acid in Japanese quails. ABSTRACT Objective This study evaluated the safety profile of tolfenamic acid following repeated oral administration in Japanese quails (Coturnix coturnix japonica) at doses of 2 and 8 mg/kg every 12 h for 7 days. Methods The 42 quails were randomly assigned to three groups. The first group (n = 6) received
Fatih Hatipoglu +6 more
wiley +1 more source

