Results 31 to 40 of about 9,630 (162)

Biomarkers and Their Possible Functions in the Intestinal Microenvironment of Chagasic Megacolon: An Overview of the (Neuro)inflammatory Process

Journal of Immunology Research, 2021
The association between inflammatory processes and intestinal neuronal destruction during the progression of Chagasic megacolon is well established. However, many other components play essential roles, both in the long-term progression and control of the
José Rodrigues do Carmo Neto, Yarlla Loyane Lira Braga, Arthur Wilson Florêncio da Costa, Fernanda Hélia Lucio, Thais Cardoso do Nascimento, Marlene Antônia dos Reis, Mara Rubia Nunes Celes, Flávia Aparecida de Oliveira, Juliana Reis Machado, Marcos Vinícius da Silva   +9 more
doaj   +1 more source

Impact of antipsychotics, antiparkinsonian drugs, and anthraquinone stimulant laxatives on severe constipation in patients with schizophrenia. [PDF]

PCN Rep
This study investigated risk factors for severe constipation in patients with schizophrenia receiving pharmacological treatment. A retrospective analysis of over 4000 inpatients revealed that high‐dose use of clozapine, haloperidol, antiparkinsonian drugs, and anthraquinone stimulant laxatives significantly increased the risk.
Nadaya T, Inaguma T, Nagao T, Ishida T.
europepmc   +2 more sources

Applications of videolaparoscopic surgery in children [PDF]

, 2001
OBJECTIVES: to present the videolaparoscopies performed by the Children's Surgery Service, and study the main indications for pediatric laparoscopic surgeries, considering advantages and disadvantages over conventional open procedures.
C. Neto, Eriberto, Carvalho, Bernardina B., Esteves, Edward, O. Neto, Miguel, Pereira, Ruy E., Terêncio Jr., Osmar   +5 more
core   +2 more sources

Shigellosis and toxic megacolon secondary to Shigella flexneri serotype 3a: The challenges of laboratory diagnosis

International Journal of Infectious Diseases, 2018
We present a rare case of Shigella flexneri bacteraemia and toxic megacolon, and discuss the challenges of conventional laboratory techniques versus molecular PCR platforms in differentiating between Shigella species and Escherichia coli.
Emma McGuire, Simon Tiberi, Holly Ciesielczuk, Mark Melzer   +3 more
doaj   +1 more source

Pseudomembranous colitis complicated with toxic megacolon after occlusion of preventive stoma

Тазовая хирургия и онкология, 2016
Toxic megacolon complicating pseudomembranous colitis is a very rare condition that confirms by a few reports. In our case report probably described a case after extraperitoneal preventive colostomy closure toxic megacolon was developed with fatal final.
P. V. Melnikov,, E. V. Yakovleva, S. V. Savenkov, D. V. Eresko   +3 more
doaj   +1 more source

Lineage analysis of circulating Trypanosoma cruzi parasites and their association with clinical forms of Chagas disease in Bolivia. [PDF]

PLoS Neglected Tropical Diseases, 2010
BACKGROUND: The causative agent of Chagas disease, Trypanosoma cruzi, is divided into 6 Discrete Typing Units (DTU): Tc I, IIa, IIb, IIc, IId and IIe. In order to assess the relative pathogenicities of different DTUs, blood samples from three different ...
Ramona del Puerto, Juan Eiki Nishizawa, Mihoko Kikuchi, Naomi Iihoshi, Yelin Roca, Cinthia Avilas, Alberto Gianella, Javier Lora, Freddy Udalrico Gutierrez Velarde, Luis Alberto Renjel, Sachio Miura, Hiroo Higo, Norihiro Komiya, Koji Maemura, Kenji Hirayama   +14 more
doaj   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, EarlyView.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Um estudo retrospectivo dos achados histopatológicos em 894 casos de megacólon: qual é a relação entre megacólon e o câncer de cólon? [PDF]

, 2003
Patients with megaesophagus (ME) have increased prevalence of cancer of the esophagus. In contrast, a higher incidence of colorectal cancer is not observed in patients with megacolon (MC).
Aranha, Alexandre Luis, Basile, Filipe Volpe, Garcia, Fabio Rogério Brosci, Garcia, Sérgio Britto, Oliveira, Enio Chaves de, Pinto, André Péra Marques, Zucoloto, Sérgio   +6 more
core   +4 more sources

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source