Results 31 to 40 of about 8,059 (213)

Rectal endometriosis presenting as toxic megacolon

Autopsy and Case Reports, 2021
Background: The bowel is the most common site of extragenital endometriosis, with involvement of the locoregional sigmoid colon and anterior rectum seen most often.
Luis Enrique Rosario Alvarado, Hisham Bahmad, Odille Mejia, Heather Hollembeak, Robert Poppiti, Lydia Howard, Kiranmayi Muddasani   +6 more
doaj  

Severe Clostridium difficile infections in intensive care units: Diverse clinical presentations

Journal of Microbiology, Immunology and Infection, 2021
Background: Clostridium difficile infections (CDIs) cause significant mortality and morbidity. Critically ill patients are susceptible to CDIs and tend to have severe CDIs, and their clinical presentations are not merely diarrhea.
Jen-Chieh Lee, Yuan-Pin Hung, Bo-Yang Tsai, Pei-Jane Tsai, Wen-Chien Ko   +4 more
doaj   +1 more source

A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection [PDF]

, 2016
Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia.
Beamer, Gillian, Curiel, David T, Debatis, Michele, Dmitriev, Igor P, Kashentseva, Elena A, Kim, Hyeun Bum, Schmidt, Diane J, Shoemaker, Charles B, Steele, Jennifer A, Sun, Xingmin, Tremblay, Jacqueline M, Tzipori, Saul, Wang, Yaunkai   +12 more
core   +2 more sources

The role of colonoscopy in the management of intestinal obstruction: a 20-year retrospective study [PDF]

, 2010
Purpose The aim of the study was to assess the use colonoscopy over time in the assessment of large bowel obstruction in a tertiary university hospital.
Konstantinos H Katsanos, Mariana Maliouki, Athina Tatsioni, Eleftheria Ignatiadou, Dimitrios K Christodoulou, Michael Fatouros, Epameinondas V Tsianos   +6 more
core   +1 more source

Risk for Clostridium difficile infection after allogeneic hematopoietic cell transplant remains elevated in the postengraftment period [PDF]

, 2017
BACKGROUND: Clostridium difficile infection (CDI) is a frequent cause of diarrhea among allogeneic hematopoietic cell transplant (HCT) recipients. It is unknown whether risk factors for CDI vary by time posttransplant.
Bommarito, Kerry M, Chiller, Tom M, DiPersio, John, Dubberke, Erik R, Fraser, Victoria J, Olsen, Margaret A, Reske, Kimberly A, Seiler, Sondra, Silveira, Fernanda P   +8 more
core   +2 more sources

Long‐term outcomes of children with ulcerative colitis after acute severe colitis: A GETAID pédiatrique multicenter study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Acute severe colitis (ASC) is a frequent and severe complication of ulcerative colitis (UC) with a high risk of colectomy. Effects of immunosuppressants and anti–tumor necrosis factor (anti‐TNF) agents on the risk of colectomy remain debated. We wished to study the evolution of French pediatric‐onset UC patients after ASC.
Manon Cochet, Agathe Beauvais, Frank Ruemmele, Raphael Enaud, Thierry Lamireau, Rémi Duclaux‐Loras, Claire Dupont, Stéphanie Willot, Laure Bridoux‐Henno, Georges Dimitrov, Julie Lemale, Vincent Guinard‐Samuel, Valérie Bertrand, Anne Breton, Christine Martinez Vinson, Stéphanie Coopman, Delphine Ley, Bénédicte Pigneur, and the Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du tube Digestif (GETAID) pédiatrique   +18 more
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Blowhole Colostomy for Clostridium difficile-Associated Toxic Megacolon

Case Reports in Surgery, 2016
We present the case of a 58-year-old man who underwent urgent blowhole colostomy for toxic megacolon (TM) secondary to Clostridium difficile infection (CDI).
Jeroen Kerstens, Ian Diebels, Charles de Gheldere, Patrick Vanclooster   +3 more
doaj   +1 more source

Profile of Trypanosoma cruzi Infection in a Tropical Medicine Reference Center, Northern Italy [PDF]

, 2014
Chagas disease (CD) is endemic in Central and South America, Mexico and even in some areas of the United States. However, cases have been increasingly recorded also in non-endemic countries.
Angheben, A, Anselmi, M, Bisoffi, Z, Buonfrate, D, Chiampan, A, Gobbi, F, Mainardi, P, Marocco, S, Postiglione, C, Repetto, E, Tais, S   +10 more
core   +3 more sources

Ionomycin Exhibits Potent and Selective Bactericidal Activity Against Clostridioides difficile Through Calcium‐Dependent Membrane Disruption

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Ionomycin exhibits potent and selective bactericidal activity against Clostridioides difficile, rapidly reducing vegetative cells, toxin production, sporulation, and spore germination while sparing representative gut microbiota. Its activity is calcium‐dependent and mediated through disruption of bacterial membrane potential, highlighting ionomycin as ...
Ahmed A. Abouelkhair, Nader S. Abutaleb, Mohamed N. Seleem   +2 more
wiley   +1 more source