Results 41 to 50 of about 5,338,541 (183)

Revisiting the vicious circle of dry eye disease: A focus on the pathophysiology of meibomian gland dysfunction [PDF]

, 2016
International audienceMeibomian gland dysfunction (MGD) is the most frequent cause of dry eye disease (DED). Eyelid inflammation, microbial growth, associated skin disorders as well as potentially severe corneal complications culminate to make MGD a ...
Akova, Yonca A, Rolando, Maurizio, Benítez-del-Castillo, José, Aragona, Pasquale, Merayo-Lloves, Jesús, Messmer, Elisabeth, Geerling, Gerd, Messmer, Elisabeth M., Benítez del Castillo Sánchez, José Manuel, Labetoulle, Marc, Baudouin, Christophe, Boboridis, Kostas G., Akova, Yonca A., Sánchez Ávila, Ronald Mauricio, Boboridis, Kostas G, Merayo Lloves, Jesús, Messmer, Elisabeth M, Benítez Del Castillo, José   +17 more
core   +1 more source

Differential characteristics among asymptomatic and symptomatic meibomian gland dysfunction and those with dry eye

BMC Ophthalmology, 2023
Purpose To identify the characteristics of asymptomatic meibomian gland dysfunction (MGD), symptomatic MGD, and MGD coexisting with dry eye disease (DED). Methods This cross sectional study enrolled a total of 153 eyes of 87 MGD patients.
Yi-Ran Chiou, Pei-Yu Lin, Yu-Bai Chou, Po-Wei Huang, Nai-Wen Fan   +4 more
doaj   +1 more source

Budget impact analysis (BIA) of the TearCare System for the treatment of meibomian gland dysfunction (MGD)-associated dry eye disease (DED) in the United States (US)

Expert Review of Ophthalmology
TearCare is an in-office procedure indicated to restore MGD and relieve DED signs and symptoms. MGD is a major cause of DED, a high prevalence condition currently treated with medical therapies including over-the-counter and prescription drops. The BIA assessed the budget impact of increasing the TearCare market share against prescription drops in ...
Thomas Chester, Roberta Longo, Cristina Masseria, Phoenix Riley, Chad Patel, Lorie Mody   +5 more
openaire   +1 more source

Low‐level light therapy for dry eye disease and meibomian gland dysfunction: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract A healthy tear film is vital for ocular surface integrity and relies on the coordinated function of the lacrimal glands, meibomian glands and conjunctival goblet cells. Dysfunction in any of these elements can lead to dry eye disease (DED). This systematic review and meta‐analysis evaluated the efficacy of low‐level light therapy (LLLT) as a ...
Sjur Reppe, Yousif Subhi, Tore Steinkjer, Mazyar Yazdani, Miriam Kolko, Tor P. Utheim, Fredrik Andreas Fineide   +6 more
wiley   +1 more source

Exploring the Microbial Changes in Meibomian Gland Dysfunction through 16S rDNA Sequencing: Eye Microbiome

, 2022
Background:  The study examines bacterial community diversity in patients with Meibomian Gland Dysfunction (MGD) using 16S rDNA sequencing, compared to healthy individuals. The goal is to understand microbial changes in MGD and provide insights into
Kavianfar, Azadeh, Salimi, Mahdieh, Taherkhani, Hamidreza   +2 more
core   +1 more source

Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond, Ronny Amamoo, Fapianey J. Alexandre, Sewedo B. Ajisegiri, Menaka C. Thounaojam, Pamela M. Martin, Ravirajsinh N. Jadeja   +6 more
wiley   +1 more source

Ductal Hyperkeratinization and Acinar Renewal Abnormality: New Concepts on Pathogenesis of Meibomian Gland Dysfunction

, 2023
Meibomian gland dysfunction (MGD) is a functional and morphological disorder of the meibomian glands which results in qualitative or quantitative alteration in meibum secretion and is the major cause of evaporative dry eye (EDE).
Ya-Li Du, You-Fan Ye, Kang-Kang Xu, Jing-Yu Qu, Xi Peng, Ming-Chang Zhang, Yang Liu, Hua Chen, Hua-Tao Xie, Jia-Song Wang, Du, Ya-Li, Liu, Yang, Zhang, Ming-Chang, Wang, Jia-Song, Qu, Jing-Yu, Xie, Hua-Tao, Xu, Kang-Kang, Ye, You-Fan, Peng, Xi, Chen, Hua   +19 more
core   +1 more source

Compounded 0.03% Tacrolimus in Cross‐Linked Hyaluronate Improves Ocular Surface Health in Dogs With Evaporative Dry Eye Disease

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective To assess the clinical effects of a compounded 0.03% tacrolimus in 0.75% cross‐linked hyaluronic acid (XHA) on tear quantity, quality, and ocular surface health in dogs with evaporative dry eye disease (EDED). Procedures Sixteen client‐owned dogs diagnosed with EDED (normal aqueous production yet reduced stability) were enrolled in ...
Lionel Sebbag, Eunice Q. A. Neta, Catharina R. de Farias, Ana Cláudia S. Raposo, Arianne P. Oriá   +4 more
wiley   +1 more source

Intense pulsed light treatment in meibomian gland dysfunction: A concise review

, 2020
Purpose To review the published literature related to application of intense pulsed light (IPL) for treating meibomian gland dysfunction (MGD). Methods The literature search included the PubMed database and used the keywords “Intense Pulsed Light and ...
Arita, Reiko, Tashbayev, Behzod, Fineide, Fredrik, Yazdani, Mazyar, Utheim, Tor Paaske   +4 more
core   +1 more source

Common Ophthalmic Conditions in Popular Dog Breeds in Japan: Insights From a Survey of 105 Veterinarians Practicing Ophthalmology

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To identify commonly presented dog breeds and potentially heritable ophthalmic diseases encountered by veterinarians practicing ophthalmology in Japan. Methods A survey was distributed through the Japanese Society of Comparative and Veterinary Ophthalmology.
Victoria Caballero, Arisu Kobayashi, Yasuyoshi Umeda, Susumu Hirashima, Yuichiro Muramatsu, Mitsuharu Ota, Makoto Yamashita, Yukako Kobayashi, Keiko Miyadera   +8 more
wiley   +1 more source