Results 1 to 10 of about 2,542 (193)
iScience, 2021 Summary: A lipid layer consisting of meibum lipids exists in the tear film and functions in preventing dry eye disease. Although the meibum lipids include diverse lipid classes, the synthesis pathway and role of each class remain largely unknown.
Megumi Sawai +7 more
doaj +2 more sources
Meibum lipid hydrocarbon chain branching and rheology after hematopoietic stem cell transplantation [PDF]
Biochemistry and Biophysics Reports, 2020 Purpose: Meibum from donors who have had hematological stem cell transplantations (MHSCT) are susceptible to severe dry eye symptoms and exhibit very high lipid order (stiffness) compared with meibum from donors without dry eye (Mn).
Poonam Mudgil +2 more
doaj +2 more sources
Frontiers in Medicine, 2022 Objective: To observe differences in meibomian gland morphology among patients with meibomian gland dysfunction (MGD) with liquid meibum, with solid meibum, and a non-MGD group by laser scanning in vivo confocal microscopy (IVCM), and then analyze the ...
Xiaowei Zhong
exaly +3 more sources
PLoS ONE, 2023 Meibomian gland dysfunction (MGD) leads to meibum stasis and pathogenic bacteria proliferation. We determined meibum microbiota via next-generation sequencing (NGS) and examined their association with tear cytokine levels in patients with MGD. This cross-
Ubonwan Rasaruck +4 more
doaj +2 more sources
Changes in meibum composition following plaque bachytherapy for choroidal melanoma [PDF]
BMJ Open Ophthalmology, 2020 Objectives Dry eye is common when external beam radiation is used for the treatment of choroidal melanoma (CM). As meibum structure and composition have been related to dry eye, we determined if plaque bachytherapy for CM alters meibum composition.Design
Aparna Ramasubramanian +2 more
doaj +3 more sources
Prevalence and Association of Meibomian Gland Dysfunction with Dry Eye Severity from a Tertiary Care Rural Hospital in Central Gujarat: A Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Meibomian glands are holocrine meibum secreting glands driving out the oil from the orifice. It forms the outermost lipid layer of the tear film which prevents overflow of tears because of its hydrophobic properties and reduces their ...
Devanshi Smit Mehta +2 more
doaj +1 more source
BMC Ophthalmology, 2022 Background In the present study, we evaluated the correlation between meibomian gland dropout and meibum quality in the same central 8 meibomian glands of the eyelid.
Minji Ha +7 more
doaj +1 more source
Candidate Molecular Compounds as Potential Indicators for Meibomian Gland Dysfunction
Frontiers in Medicine, 2022 Meibomian gland dysfunction (MGD) is the leading cause of dry eye disease throughout the world. Studies have shown that several molecules in meibum, including but not limited to interleukins, amino acids, cadherins, eicosanoids, carbohydrates, and ...
Kofi Asiedu
doaj +1 more source
Metagenomic profiling of ocular surface microbiome changes in Demodex blepharitis patients
Frontiers in Cellular and Infection Microbiology, 2022 PurposeTo compare the ocular surface and meibum microbial communities of humans with Demodex Blepharitis (DB) and healthy controls.MethodsConjunctival sac and meibum samples from 25 DB patients and 11 healthy controls were analyzed using metagenomic next-
Yana Fu +12 more
doaj +1 more source
Latest developments on meibomian gland dysfunction: Diagnosis, treatment and management
African Vision and Eye Health, 2022 Background: Meibomian gland dysfunction (MGD) is one of the leading causes of evaporative dry eye disease and one of the most common ophthalmic conditions found in clinical practice.
Solani D. Mathebula
doaj +1 more source