Results 41 to 50 of about 2,542 (193)
The Microbiome of the Meibum and Ocular Surface in Healthy Subjects
Investigative Opthalmology & Visual Science, 2020 The purpose of this study was to investigate the microbiome in the meibum, conjunctival sac, and eyelid skin in young and elderly healthy subjects, and analyze the effect that age, sex, and region have on microbiome composition.This study involved 36 healthy subjects (young-age subjects: 9 men/9 women, age range: 20-35 years; elderly age subjects: 9 ...
Suzuki, Tomo +4 more
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Role of meibum and tear phospholipids in the evaporative water loss associated with dry eye. [PDF]
, 2021 It is generally believed that the tear film lipid surface film inhibits the rate of evaporation (Revap) of the underlying tear aqueous. It is also generally believed that changes in the composition of the tear film lipid layer is responsible for an ...
Sledge, Samiyyah M
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Journal of Lipid Research, 2018 The lipid composition of human meibomian gland secretions (meibum) has been analyzed using both targeted and untargeted mass spectrometric approaches, each of which has its advantages and disadvantages.
Jianzhong Chen, Kelly K. Nichols
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On the Presence and Role of Polar Lipids in Meibum [PDF]
Investigative Opthalmology & Visual Science, 2010 I read with interest the paper by Chen et al.1 published online on July 29, 2010. The paper is concerned with shotgun (or direct-infusion) lipidomic analysis of normal human meibum by means of electrospray ionization mass spectrometry. I noticed with pleasure that Chen et al., along with providing new and important information on the meibomian lipidome,
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Journal of Lipid Research, 2014 As current diagnostic markers for dry eye syndrome (DES) are lacking in both sensitivity and specificity, a pressing concern exists to develop activity markers that closely align with the principal axes of disease progression.
Sin Man Lam +9 more
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Lipid conformational order and the etiology of cataract and dry eye
Journal of Lipid Research, 2021 Lens and tear film lipids are as unique as the systems they reside in. The major lipid of the human lens is dihydrosphingomylein, found in quantity only in the lens.
Douglas Borchman
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Lipid polarity gradient formed by ω-hydroxy lipids in tear film prevents dry eye disease
eLife, 2020 Meibum lipids form a lipid layer on the outermost side of the tear film and function to prevent water evaporation and reduce surface tension. (O-Acyl)-ω-hydroxy fatty acids (OAHFAs), a subclass of these lipids, are thought to be involved in connecting ...
Masatoshi Miyamoto +3 more
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, 2022 Sphingolipids (SPL) are a class of lipid molecules that play important functional and structural roles in our body and are a component of meibum. Sphingomyelinases (SMases) are key enzymes in sphingolipid metabolism that hydrolyze sphingomyelin (SM) and ...
Mondal, Koushik +9 more
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Changes in Meibum Lipid Composition With Ocular Demodex Infestation
Translational Vision Science & Technology, 2021 The purpose of this study was to understand the impact of Demodex infection in the lipid component of meibum in patients.The meibum samples were collected from four groups of subjects: (1) Demodex-negative with non-MGD (D-M-; n = 10); (2) Demodex-positive with non-MGD (D+M-; n = 10); (3) Demodex-negative with MGD (D-M+; n = 10); and (4) Demodex ...
Gao, Hui +5 more
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Correction: The Combined Impact of Intense Pulsed Light Combined and 3% Diquafosol Ophthalmic Solution on Evaporative Dry Eye: A Randomized Control Study [PDF]
, 2023 In the sentence beginning “Meibomian gland function and secretion quality:…” in this article, the values “…five meibomian glands in the middle parts of the eyelid were assessed using a scale of 0 to 3 for each gland (0 represented clear meibum; 1 ...
Qin, Guanghao +35 more
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