Results 61 to 70 of about 2,542 (193)
Protein-to-Lipid Ratio of Meibum as a Metric for Meibomian Gland Dysfunction [PDF]
, 2016 Dry eye disease is a condition caused by inadequate moisture levels in the eye that may result from one of two prevalent situations: reduced tear production, or imbalance in tear composition.
Potma, PhD, Eric, Ortiz, Isabel
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Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Advanced Materials, Volume 38, Issue 51, 11 September 2026.Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
, 2019 Sphingolipids (SPL) play roles in cell signaling, inflammation, and apoptosis. Changes in SPL composition have been reported in individuals with MGD, but associations between clinical signs of MGD and compositional changes in meibum SPLs have not been ...
Mandal, Nawajes +6 more
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iMeta, Volume 5, Issue 4, August 2026.Micro‐ and nano‐plastics (MNPs) can enter the human body through inhalation, ingestion, contact with consumer products, and iatrogenic routes. The clinical relevance of MNP exposure should be interpreted at three levels: barrier interaction, cellular stress, and system‐level disruption, with key mechanisms including oxidative stress, mitochondrial ...
Chen Tu +29 more
wiley +1 more source
Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia
Clinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise +5 more
wiley +1 more source
Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease
Acta Ophthalmologica, Volume 104, Issue 1, Page e28-e38, February 2026.Abstract Purpose To examine ocular surface changes and inflammatory tear fluid biomarkers in patients with thyroid eye disease (TED). Methods We included 106 Graves' disease (GD) patients (36 without TED, 32 with active and 38 with inactive TED) and 106 age‐ and sex‐matched healthy subjects for ophthalmological evaluation, including ocular surface ...
Mikael Thomassen Neset +13 more
wiley +1 more source
A machine learning framework to analyze hyperspectral stimulated Raman scattering microscopy images of expressed human meibum [PDF]
, 2017 We develop and discuss a methodology for batch-level analysis of hyperspectral stimulated Raman scattering (hsSRS) data sets of human meibum in the CH-stretching vibrational range. The analysis consists of two steps. The first step uses a training set (n=
Sumit Garg +11 more
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, 2023 BackgroundThere is a need to develop biomarkers for diagnosis and prediction of treatment responses in depression and post‐traumatic stress disorder (PTSD).MethodsCross‐sectional study examining correlations between tear inflammatory proteins, meibum and
Felix, Elizabeth +10 more
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Journal of Lipid Research, 2014 The tear film covers the anterior eye and the precise balance of its various constituting components is critical for maintaining ocular health. The composition of the tear film amphiphilic lipid sublayer, in particular, has largely remained a matter of ...
Sin Man Lam +5 more
doaj +1 more source
A Meibomian Gland Concretion Presenting as a Palpable Eyelid Mass: A Rare Case Report
Case Reports in Ophthalmological Medicine, Volume 2026, Issue 1, 2026.Background Meibomian gland obstruction is a condition in which lipid secretions accumulate within the meibomian gland duct because of blockage of the gland orifice, leading to inflammation and the formation of a nodular lesion. In most cases, whitish lipid material can be observed at the eyelid margin. However, the formation of a true concretion within
Daisuke Hasegawa +5 more
wiley +1 more source