Results 71 to 80 of about 2,542 (193)

In Vitro Inhibition of Evaporation with Perfluorohexyloctane, an Eye Drop for Dry Eye Disease

Current Therapeutic Research, 2023
: Objective: Perfluorohexyloctane (PFHO) MIEBOTM, formerly (NOV03) is a single component, water-free eye drop approved by the Food and Drug Administration in the United States for the treatment of dry eye disease.
Jason Vittitow, Ph.D., Robert Kissling, M.D., Heleen DeCory, Ph.D., Douglas Borchman, Ph.D.   +3 more
doaj   +1 more source

The Investigation of Plasma Natriuretic Peptide as Inflammatory Biomarker Predictor in Coronary Heart Disease Patients With Dry Eye Disease: A Case–Control Study

International Journal of Inflammation, Volume 2026, Issue 1, 2026.
Background Inflammation contributes to both coronary heart disease (CHD) and dry eye disease (DED). Recognizing the relationship between CHD and DED is critical for maintaining ocular health in CHD patients. As a result, early monitoring of natriuretic peptides and inflammatory biomarkers may help minimize DED in CHD patients.
Amani Y. Alhalwani, Ibrahim Alsaggaf, Abdulrahman Alidroos, Farouk W. Kattan, Talal Y. Almarzouki, Sarah Shawli, Maryam Hashem Shawish, Shatha M. Jambi, Jumanah Abdali, Mohammed Fawaz Qutub, Newman Osafo   +10 more
wiley   +1 more source

Effects of Lipid Saturation on the Surface Properties of Human Meibum Films [PDF]

International Journal of Molecular Sciences, 2018
Elevated levels of acyl chain saturation of meibomian lipids are associated with vastly different effects: from enhanced tear film (TF) stability in infants to shortened TF breakup time in meibomian gland disease patients. Thus it is important to study the effect of saturation on the surface properties of human meibum (MGS). Therefore, MGS films (1, 2,
Yana Nencheva, Aparna Ramasubramanian, Petar Eftimov, Norihiko Yokoi, Douglas Borchman, Georgi As. Georgiev   +5 more
openaire   +2 more sources

Number of expressible glands and meibum quality as function of time.

, 2022
Time: 0 = Tx 1, 2 weeks = Tx 2, 4 weeks = Tx 3, 6 weeks = Tx 4; A. Number of expressible gland in lower lids (A1) and upper lids (A2). Error bars: SEM; ***: P (between arms) < 0.001; ****: P (between arms)
Rolando Toyos (12915006), Neel R. Desai (12915009), Steven J. Dell (12915015), Melissa Toyos (12915012)   +3 more
core   +1 more source

Combined use of 0.1% fluorometholone and meibomian gland expression improves symptoms of moderate and severe dry eye disease, even in patients with systemic immune disease

Biotechnology & Biotechnological Equipment, 2019
This study prospectively evaluated the effect of 0.1% fluorometholone (FML) combined with meibomian gland expression (MGX) on dry eye disease (DED) and meibomian gland dysfunction (MGD).The study included 48 patients (96 eyes) with moderate to severe DED.
Xuming Guo, Aipeng Li, Yi Fan, Yanru Yu, Wenhui Guo, Ying Jie   +5 more
doaj   +1 more source

Clinical and Meibomian Lipidomic Changes After Combined Intense Pulsed Light and Triamcinolone Acetonide Therapy for Chalazion: A Retrospective Single‐Arm Pre–Post Case Series

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Purpose To explore the clinical changes associated with intense pulsed light (IPL) combined with triamcinolone acetonide (TA) injections in patients with chalazion and to evaluate associated changes in Hospital Anxiety and Depression Scale (HADS) scores and meibomian gland lipid profiles.
Zhenhe Dong, Linxiao Wu, Cheng Zhang, Ran Feng, Huilan Zhang, Yongmei Sang, Yong Tao, Yan Zhang, Tao Zhang, Hong Liang   +9 more
wiley   +1 more source

Lipids of human meibum: mass-spectrometric analysis and structural elucidation [PDF]

Journal of Lipid Research, 2007
The purpose of this study was to structurally characterize the major lipid species present in human meibomian gland secretions (MGS) of individual subjects by means of ion trap atmospheric pressure ionization mass spectrometry analysis (API MS(n)).
Igor A, Butovich, Eduardo, Uchiyama, James P, McCulley   +2 more
openaire   +2 more sources

Analysis of Cytokine Levels in Meibum and Clinical Correlations with Meibomian Gland Dysfunction

Disease Markers, 2022
Objectives. This study is aimed at investigating the difference of meibum chemokines in MGD subjects with different degrees of MGD and the correlations of meibum chemokines with ocular surface parameters. Methods. Twenty MGD subjects (MQ score > 8
Wenting Liu, Tong Lin, Lan Gong
openaire   +2 more sources

An Intact Ex Vivo Pigskin Model for Evaluating Topical Treatments for Blepharitis‐Associated Biofilms

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Importance Blepharitis is a chronic inflammatory condition of the eyelid margin that impacts millions of adults and children. Its etiology is unclear, and its treatment remains unsatisfactory. Objective To develop an intact ex vivo pigskin model to evaluate the etiology of and to determine effective treatments for blepharitis.
Aaron Strickland, James Gras, Ellen Lantz, Richard Eiferman, Anthony Sawyer, George Rodeheaver, Nilufer Yesilirmak   +6 more
wiley   +1 more source

The Influence of Chalazion History on Meibomian Gland Loss and DED

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Objective To investigate the impact of chalazion history on meibomian gland loss and dry eye disease (DED). Methods This study was a retrospective case–control study. Sixty patients with a history of chalazion admitted to a certain hospital from June 2021 to June 2024, who were selected as the previous chalazion group, and another 90 patients with no ...
Ying Liu, Ying Zhou, Chong Xu, Tu Su, Sudhir Patel   +4 more
wiley   +1 more source