Results 21 to 30 of about 2,542 (193)

Atomic force microscopy and Langmuir–Blodgett monolayer technique to assess contact lens deposits and human meibum extracts [PDF]

Journal of Optometry, 2015
Purpose: The purpose of this exploratory study was to investigate the differences in meibomian gland secretions, contact lens (CL) lipid extracts, and CL surface topography between participants with and without meibomian gland dysfunction (MGD). Methods:
Sarah Hagedorn, Elizabeth Drolle, Holly Lorentz, Sruthi Srinivasan, Zoya Leonenko, Lyndon Jones   +5 more
doaj   +2 more sources

Meibomian Gland Shortening Is Associated With Altered Meibum Composition [PDF]

Investigative Ophthalmology & Visual Science
The purpose of this study was to investigate differences in the composition of meibum extracted from human meibomian glands displaying different morphological characteristics.Adult participants with evidence of meibomian gland shortening were enrolled. Glands were observed using infrared meibography, and meibum was collected from one short and one long
Iqbal, F, Stapleton, F, Masoudi, S, Papas, EB, Tan, J   +4 more
openaire   +4 more sources

Sebum/Meibum Surface Film Interactions and Phase Transitional Differences

Investigative Opthalmology & Visual Science, 2016
Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of sebum is due to squalene (SQ); and if sebum or SQ, a major component of sebum,
Mudgil, Poonam (R10383), Borchman, Douglas, Gerlach, Dylan, Yappert, Marta C.   +3 more
openaire   +4 more sources

Characteristics of Patients with Refractory Meibomian Gland Dysfunction Unresponsive to Intense Pulsed Light Treatment Using a Vascular Filter [PDF]

Diagnostics
Objectives: To investigate the clinical characteristics of patients with meibomian gland dysfunction (MGD) who are refractory to additional intense pulsed light (IPL) treatment.
Yoo Young Jeon, Nahyun Park, Yea Eun Lee, Chung Min Lee, Sanghyu Nam, Changmin Kim, Ryunhee Lee, Ji Yoon Park, Kyu Sang Eah, Ho Seok Chung, Jae Yong Kim, Hun Lee   +11 more
doaj   +2 more sources

Diurnal Variation of Tear and Meibum Lipids in Healthy Subjects. [PDF]

Ophthalmic Physiol Opt
Abstract Purpose To determine whether the lipid composition of tears and meibum demonstrates diurnal variation in healthy individuals, with emphasis on the relative distribution of lipid classes.
Kumar M, Raj A, Vijay AK, Dumpati S, Masoudi S, Willcox M.   +5 more
europepmc   +2 more sources

Alterations in the composition of meibomian gland secretions in patients with meibomian gland dysfunction based on Raman spectroscopy [PDF]

Frontiers in Medicine
PurposeTo investigate biochemical alterations in meibum from patients with obstructive meibomian gland dysfunction (MGD) using Raman spectroscopy, with a focus on lipid saturation, molecular conformation, and lipid–protein composition.MethodsMeibum ...
Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Lingli Zhang, Lingli Zhang, Yiming Wu, Yiming Wu, Dan Yang, Dan Yang, Naikun Jiang, Naikun Jiang, Ting Mao, Ting Mao, Xueer Zheng, Xueer Zheng, Hao Gu, Hao Gu, Liying Zhang, Liying Zhang   +19 more
doaj   +2 more sources

Human tear film and meibum. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum [PDF]

Journal of Lipid Research, 2009
Human meibum was targetly analyzed for the presence of intact wax esters (WEs) and related compounds by means of reverse-phase HPLC in combination with ion trap mass spectrometry.
Igor A. Butovich, Jadwiga C. Wojtowicz, Mike Molai   +2 more
doaj   +3 more sources

Impact of smoking exposure on meibomian gland morphology and tear film stability: a cross-sectional study [PDF]

Frontiers in Medicine
PurposeTo investigate the effects of smoking on the structure and function of the meibomian glands.MethodsA total of 104 chronic smokers (with a smoking history of more than 5 years) and 44 healthy non-smokers were included.
Ting Chen, Ruidong Wang, Shuxian Liang, Jingting Feng   +3 more
doaj   +2 more sources

Abnormal meibum is associated with SREBF1 mutation and IFAP Syndrome-2. [PDF]

Exp Eye Res
Abstract The X-linked Ichthyosis Follicularis, Alopecia, and Photophobia syndrome type-2 (IFAP-2), is a condition that has been linked to a c.1579C>T mutation in the SREBF1 gene. However, the molecular implications of the mutation in Meibomian glands (MG) remain unknown.
Butovich IA, Schatz M, Saboo US, Wojtowicz JC, Johnson DA.   +4 more
europepmc   +4 more sources

The Meibomian Gland Composite Score (MGCS): A Novel Grading System Integrating Existing Scales for Meibomian Gland Dysfunction [PDF]

Clinical Optometry
Kaleb S Abbott,1 Anna A Tichenor,2 Stephanie Martich,1 Andrew D Pucker31Department of Ophthalmology, Sue-Anschutz Rodgers Eye Center, University of Colorado School of Medicine, Aurora, CO, USA; 2School of Optometry, Indiana University, Bloomington, IN ...
Abbott KS, Tichenor AA, Martich S, Pucker AD   +3 more
doaj   +1 more source