Results 31 to 40 of about 107,801 (310)
m6A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis
Nature Communications, 2019 Despite the vast number of modification sites mapped within mRNAs, known examples of consequential mRNA modifications remain rare. Here, we provide multiple lines of evidence to show that Ime4p, an N6-methyladenosine (m6A) methyltransferase required for ...
G. Guy Bushkin +7 more
semanticscholar +1 more source
The Arabidopsis Cdk1/Cdk2 homolog CDKA;1 controls chromosome axis assembly during plant meiosis
EMBO Journal, 2019 Meiosis is key to sexual reproduction and genetic diversity. Here, we show that the Arabidopsis cyclin‐dependent kinase Cdk1/Cdk2 homolog CDKA;1 is an important regulator of meiosis needed for several aspects of meiosis such as chromosome synapsis.
C. Yang +14 more
semanticscholar +1 more source
Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I
Journal of Cell Biology, 2019 Meiosis with a single round of DNA replication and two successive rounds of chromosome segregation requires specific cyclins associated with cyclin-dependent kinases (CDKs) to ensure its fidelity.
Yufei Li +16 more
semanticscholar +1 more source
Meiosis in Bougainvillea [PDF]
Nature, 1947 A query concerning the possibilities of crossing various horticultural varieties of Bougainvillea led me to examine meiosis in several of the more important ones available in Jamaica. Six varieties, Snow White, Formosa, Dark Purple, Ruby, Orange King and Royal Purple, were used.
openaire +3 more sources
Science Advances, 2019 The histone modification reader ZCWPW1 guides male meiosis prophase I. Meiosis is a specialized type of cell division that creates haploid germ cells and ensures their genetic diversity through homologous recombination.
Miao Li +17 more
semanticscholar +1 more source
The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis
Biology, 2017 Mistakes during cell division frequently generate changes in chromosome content, producing aneuploid or polyploid progeny cells. Polyploid cells may then undergo abnormal division to generate aneuploid cells.
T. Potapova, G. Gorbsky
semanticscholar +1 more source
Meiosis: How Male Flies Do Meiosis [PDF]
Current Biology, 2002 In meiosis in male fruitflies, chromosome pairing events do not facilitate genetic exchange, but rather create bivalents that can be sequestered to discrete pockets of the prophase nucleus. This assignment of homologs to a common pocket likely facilitates the orientation of homologous centromeres to opposite poles.
openaire +3 more sources
Meiosis in male Drosophila [PDF]
Spermatogenesis, 2012 Meiosis entails sorting and separating both homologous and sister chromatids. The mechanisms for connecting sister chromatids and homologs during meiosis are highly conserved and include specialized forms of the cohesin complex and a tightly regulated homolog synapsis/recombination pathway designed to yield regular crossovers between homologous ...
Rihui Yan, Bruce D. McKee, Jui-He Tsai
openaire +3 more sources
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Nature Communications, 2016 Sexual reproduction is crucially dependent on meiosis, a conserved, specialized cell division programme that is essential for the production of haploid gametes.
Emilie Abby +12 more
semanticscholar +1 more source