Results 31 to 40 of about 185,285 (413)
Molecular Cell, 2003 Degradation of mitotic cyclins is critical for exit from mitosis. Recent studies in budding yeast address the role of cyclin degradation in meiosis. Cyclin stabilization in meiosis I interferes with anaphase I spindle disassembly but, surprisingly, does not halt progression into meiosis II.
openaire +3 more sources
Epilepsia Open, EarlyView., 2022 Abstract Rodent models of epilepsy remain the cornerstone of research into the mechanisms underlying genetic epilepsy. Reproducibility of experiments using these rodent models, occurring across a diversity of laboratories and commercial vendors, remains an issue impacting the cost‐effectiveness and scientific rigor of the studies performed.
Massimo Mantegazza +7 more
wiley +1 more source
Co-evolution of the mitotic and meiotic modes of eukaryotic cellular division [PDF]
Physical Review E 98 (2018), 032409, 2018 The genetic material of a eukaryotic cell comprises both nuclear DNA (ncDNA) and mitochondrial DNA (mtDNA). These differ markedly in several aspects but nevertheless must encode proteins that are compatible with one another. Here we introduce a network model of the hypothetical co-evolution of the two most common modes of cellular division for ...
arxiv +1 more source
The meiosis-specific Cdc20 family-member Ama1 promotes binding of the Ssp2 activator to the Smk1 MAP kinase. [PDF]
, 2018 Smk1 is a meiosis-specific MAP kinase (MAPK) in budding yeast that is required for spore formation. It is localized to prospore membranes (PSMs), the structures that engulf haploid cells during meiosis II (MII).
Diamond, Aviva +5 more
core +3 more sources
Cell Reports, 2012 In meiosis, two specialized cell divisions allow the separation of paired chromosomes first, then of sister chromatids. Separase removes the cohesin complex holding sister chromatids together in a stepwise manner from chromosome arms in meiosis I, then ...
Sandra A. Touati +10 more
doaj +1 more source
Dynamic Histone H3 Modifications Regulate Meiosis Initiation via Respiration
Frontiers in Cell and Developmental Biology, 2021 Meiosis is essential for genetic stability and diversity during sexual reproduction in most eukaryotes. Chromatin structure and gene expression are drastically changed during meiosis, and various histone modifications have been reported to participate in
Jian Shi +6 more
doaj +1 more source
Chromosome segregation in plant meiosis [PDF]
, 2014 Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
De Storme, Nico +4 more
core +2 more sources
Wellcome Open Research, 2019 Background: Meiosis produces gametes through two successive nuclear divisions, meiosis I and meiosis II. In contrast to mitosis and meiosis II, where sister chromatids are segregated, during meiosis I, homologous chromosomes are segregated. This requires
Stefan Galander +3 more
doaj +1 more source
The Cyclin B2/CDK1 Complex Conservatively Inhibits Separase Activity in Oocyte Meiosis II
Frontiers in Cell and Developmental Biology, 2021 Recently, we have reported that the cyclin B2/CDK1 complex regulates homologous chromosome segregation through inhibiting separase activity in oocyte meiosis I, which further elucidates the compensation of cyclin B2 on cyclin B1’s function in meiosis I ...
Jian Li +7 more
doaj +1 more source
Defining the developmental program leading to meiosis in maize
Science, 2018 Following meiosis in maize Plants do not set aside a germ-cell lineage from early development as animals do, but instead generate germ cells on demand.
B. Nelms, V. Walbot
semanticscholar +1 more source