Results 101 to 110 of about 30,580 (249)

Anther development and pollen fertility in a polyploid cultivar of Platanus × acerifolia Willd. 'Huanong Panlong'

Ornamental Plant Research
Platanus, a key species in urban landscaping, is a classic allopolyploid with three distinct subgenomes. Polyploidization often induces meiotic irregularities, offering promising opportunities for breeding improved ornamental cultivars with suppressed ...
Zhiru Bao, Hui Long, Bei Li, Changsheng Shao, Jiaqi Zhang, Manzhu Bao   +5 more
doaj   +1 more source

Histone H2AFX Links Meiotic Chromosome Asynapsis to Prophase I Oocyte Loss in Mammals.

PLoS Genetics, 2015
Chromosome abnormalities are common in the human population, causing germ cell loss at meiotic prophase I and infertility. The mechanisms driving this loss are unknown, but persistent meiotic DNA damage and asynapsis may be triggers.
Jeffrey M Cloutier, Shantha K Mahadevaiah, Elias ElInati, André Nussenzweig, Attila Tóth, James M A Turner   +5 more
doaj   +1 more source

Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang, Anh Hoang Pham, Mengjiao Luo, Masahito Ikawa, Haruhiko Miyata   +4 more
wiley   +1 more source

Vitrification of human immature oocytes before and after in vitro maturation: a review [PDF]

, 2017
The use of immature oocytes subjected to in vitro maturation (IVM) opens interesting perspectives for fertility preservation where ovarian reserves are damaged by pathologies or therapies, as in PCO/PCOS and cancer patients. Human oocyte cryopreservation
Ashourzadeh, S, Khalili, Ma, Macchiarelli, G, Nottola, Sa, Palmerini, Mg, Shahedi, A   +5 more
core   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

The chromosomal challenge of human embryos: Mechanisms and fundamentals

HGG Advances
Summary: Chromosomal abnormalities in human pre-implantation embryos, originating from either meiotic or mitotic errors, present a significant challenge in reproductive biology.
Anna Ivanova, Elena Korchivaia, Maria Semenova, Igor Lebedev, Ilya Mazunin, Ilya Volodyaev   +5 more
doaj   +1 more source

The role of Merlin in spermatogenesis [PDF]

, 2008
Background Drosophila Merlin, the homolog of the human Neurofibromatosis 2 (NF2) gene, is important for the regulation of cell proliferation and receptor endocytosis. Male flies carrying a Mer3 allele, a missense mutation (Met177→Ile) in the Merlin gene,
Omelyanchuk Leonid V, Gubanova Natalia V, Yudina Olga S, Kopyl Sergei A, Akhmametyeva Elena M, Dorogova Natalia V, Chang Long-Sheng   +6 more
core   +1 more source

Influence of spermatogenic profile and meiotic abnormalities on reproductive outcome of infertile patients

Reproductive BioMedicine Online, 2005
Genetic aspects of male infertility and the possible risks of new assisted reproduction and their influence on the development of zygotes and children born after intracytoplasmic sperm injection (ICSI) need further research. These patients have an increased risk of diploidy, and disomies are frequent in their spermatozoa.
Pedro N, Barri, Jose M, Vendrell, Francisca, Martinez, Buenaventura, Coroleu, Begoña, Arán, Anna, Veiga   +5 more
openaire   +2 more sources

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source

Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances

Andrology, EarlyView.
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang, Di Liu, Guoqiang Liu, Minggang Zhu, Feng Pan   +4 more
wiley   +1 more source