Results 91 to 100 of about 33,318 (207)
During meiotic prophase, a structure called the synaptonemal complex (SC) assembles at the interface between aligned pairs of homologous chromosomes, and crossover recombination events occur between their DNA molecules.
Divya Pattabiraman +3 more
doaj +1 more source
ABSTRACT Programmed DNA double‐strand breaks (DSBs) initiate meiotic recombination at discrete genomic hotspots, and their precise mapping is crucial for understanding the molecular regulation of genome stability and evolution. A variety of genome‐wide methods have been developed, each leveraging different biochemical principles — from direct capture ...
Jianqiang Bao
wiley +1 more source
Regulation of Meiotic Recombination [PDF]
Meiotic recombination results in the heritable rearrangement of DNA, primarily through reciprocal exchange between homologous chromosome or gene conversion. In plants these events are critical for ensuring proper chromosome segregation, facilitating DNA repair and providing a basis for genetic diversity.
openaire +2 more sources
In arthropods, thelytokous parthenogenesis, in which females develop from unfertilised eggs, is often associated with reproductive manipulation by endosymbiotic bacteria such as Wolbachia and Cardinium. This study investigated whether thelytokous parthenogenesis in two mite species, Amblyseius herbicolus (Phytoseiidae) and Czenspinskia ...
Keshi Zhang, Zhi‐Qiang Zhang
wiley +1 more source
Advances in large DNA fragment assembly for microbial cell factory engineering
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Meiotic crossover recombination is essential for both accurate chromosome segregation and the generation of new haplotypes for natural selection to act upon. This requirement is known as crossover assurance and is one example of crossover control.
Bhumil Patel +5 more
doaj +1 more source
Technologies for engineering repetitive DNA
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley +1 more source
DNA double-strand breaks (DSBs) activate DNA damage responses (DDRs) in both mitotic and meiotic cells. A single-stranded DNA (ssDNA) binding protein, Replication protein-A (RPA) binds to the ssDNA formed at DSBs to activate ATR/Mec1 kinase for the ...
Arivarasan Sampathkumar +5 more
doaj +1 more source
To maintain the integrity of the genome, meiotic DNA double strand breaks (DSBs) need to form by the meiosis-specific nuclease Spo11 and be repaired by homologous recombination.
Benjamin Alleva +4 more
doaj +1 more source
Molecular insights and translational opportunities to enhance heat tolerance in rice
Abstract Heat stress is an increasingly serious threat to rice (Oryza sativa L.) productivity, yet the genetic and regulatory architecture underlying thermotolerance remain poorly resolved and fragmented across studies. Earlier research focused on individual pathways or specific developmental stages; however, recent advances now support an integrated ...
Prabhat Rana +7 more
wiley +1 more source

