Results 41 to 50 of about 61,553 (233)

The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans.

open access: yesPLoS Genetics, 2023
During meiotic prophase, the essential events of homolog pairing, synapsis, and recombination are coordinated with meiotic progression to promote fidelity and prevent aneuploidy.
Anna E Russo   +7 more
doaj   +1 more source

Local chromosome context is a major determinant of crossover pathway biochemistry during budding yeast meiosis

open access: yeseLife, 2016
The budding yeast genome contains regions where meiotic recombination initiates more frequently than in others. This pattern parallels enrichment for the meiotic chromosome axis proteins Hop1 and Red1.
Darpan Medhi   +2 more
doaj   +1 more source

Effect of Temperature and Maternal Age on Recombination Rate in Cattle

open access: yesFrontiers in Genetics, 2021
Meiotic recombination is a fundamental biological process that facilitates meiotic division and promotes genetic diversity. Recombination is phenotypically plastic and affected by both intrinsic and extrinsic factors.
Botong Shen   +7 more
doaj   +1 more source

Errors in chromosome segregation during oogenesis and early embryogenesis [PDF]

open access: yes, 2010
Errors in chromosome segregation occurring during human oogenesis and early embryogenesis are very common. Meiotic chromosome development during oogenesis is subdivided into three distinct phases.
A Dyban   +65 more
core   +1 more source

Dot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptor. [PDF]

open access: yesPLoS Genetics, 2013
During meiosis, accurate chromosome segregation relies on the proper interaction between homologous chromosomes, including synapsis and recombination. The meiotic recombination checkpoint is a quality control mechanism that monitors those crucial events.
David Ontoso   +4 more
doaj   +1 more source

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

open access: yes, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad   +102 more
core   +2 more sources

The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis.

open access: yesPLoS Genetics, 2016
Meiotic recombination is essential for the repair of programmed double strand breaks (DSBs) to generate crossovers (COs) during meiosis. The efficient processing of meiotic recombination intermediates not only needs various resolvases but also requires ...
Ye Hong   +6 more
doaj   +1 more source

Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes.

open access: yesPLoS Genetics, 2020
Meiotic recombination is essential for faithful segregation of homologous chromosomes during gametogenesis. The progression of recombination is associated with dynamic changes in meiotic chromatin structures.
Kazumasa Takemoto   +6 more
doaj   +1 more source

Evidence that MEK1 positively promotes interhomologue double-strand break repair [PDF]

open access: yes, 2010
During meiosis there is an imperative to create sufficient crossovers for homologue segregation. This can be achieved during repair of programmed DNA double-strand breaks (DSBs), which are biased towards using a homologue rather than sister chromatid as ...
Bishop-Bailey, A   +5 more
core   +1 more source

Meiotic recombination mechanisms

open access: yesComptes Rendus. Biologies, 2016
Meiosis is a specialized cell division at the origin of the haploid cells that eventually develop into the gametes. It therefore lies at the heart of Mendelian heredity. Recombination and redistribution of the homologous chromosomes arising during meiosis constitute an important source of genetic diversity, conferring to meiosis a particularly ...
openaire   +4 more sources

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