Results 21 to 30 of about 33,318 (207)
A simple model for the influence of meiotic conversion tracts on GC content. [PDF]
PLoS ONE, 2011 A strong correlation between GC content and recombination rate is observed in many eukaryotes, which is thought to be due to conversion events linked to the repair of meiotic double-strand breaks. In several organisms, the length of conversion tracts has
Marie-Claude Marsolier-Kergoat
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Probing Meiotic Recombination Decisions [PDF]
Developmental Cell, 2008 Meiotic recombination promotes genetic variation by mixing parental alleles. Two recent studies, one in this issue of Developmental Cell, have applied microarray-based methods that allow analysis of nearly all of the recombination events occurring in a single meiosis.
Roig, Ignasi, Keeney, Scott
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H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis
Cell Reports, 2015 Meiotic recombination hotspots are associated with histone post-translational modifications and open chromatin. However, it remains unclear how histone modifications and chromatin structure regulate meiotic recombination. Here, we identify acetylation of
Jialei Hu +7 more
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BMC Genomics, 2021 Background Meiosis is a specialized cell division that underpins sexual reproduction in most eukaryotes. During meiosis, interhomolog meiotic recombination facilitates accurate chromosome segregation and generates genetic diversity by shuffling parental ...
Jiyue Huang +3 more
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PLoS Genetics, 2008 Heterozygous mutations in the tumor suppressor BRCA2 confer a high risk of breast and other cancers in humans. BRCA2 maintains genome stability in part through the regulation of Rad51-dependent homologous recombination. Much about its precise function in
Martha Klovstad +2 more
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Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
Nature Communications, 2018 Homologous recombination ensures genome integrity during meiotic recombination. Here the authors reveal that factors SWS1 and SWSAP1 are critical for meiotic homologues recombination, particularly in promoting assembly of RAD51 and DMC1 on early ...
Carla M. Abreu +5 more
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The PHD finger protein Spp1 has distinct functions in the Set1 and the meiotic DSB formation complexes. [PDF]
PLoS Genetics, 2018 Histone H3K4 methylation is a feature of meiotic recombination hotspots shared by many organisms including plants and mammals. Meiotic recombination is initiated by programmed double-strand break (DSB) formation that in budding yeast takes place in gene ...
Céline Adam +10 more
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Manipulation of Meiotic Recombination to Hasten Crop Improvement
Biology, 2022 Reciprocal (cross-overs = COs) and non-reciprocal (gene conversion) DNA exchanges between the parental chromosomes (the homologs) during meiotic recombination are, together with mutation, the drivers for the evolution and adaptation of species.
Ian Fayos +5 more
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Initiation of Meiotic Recombination in Mammals [PDF]
Genes, 2010 Meiotic recombination is initiated by the induction of programmed DNA double strand breaks (DSBs). DSB repair promotes homologous interactions and pairing and leads to the formation of crossovers (COs), which are required for the proper reductional segregation at the first meiotic division.
Rajeev Kumar, Bernard De Massy
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Genetics and Molecular Biology, 2003 The Escherichia coli RecA protein (RecAp) has been demonstrated to induce mutagenesis in yeast cells, although there is still little information on the role of the RecAp in yeast recombination events.
Marcos Antonio de Morais Junior +2 more
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