Results 21 to 30 of about 247,794 (231)

Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase.

PLoS Genetics, 2022
During meiosis, recombination between homologous chromosomes (homologs) generates crossovers that promote proper segregation at the first meiotic division. Recombination is initiated by Spo11-catalyzed DNA double strand breaks (DSBs). 5' end resection of
Andrew Ziesel, Qixuan Weng, Jasvinder S Ahuja, Abhishek Bhattacharya, Raunak Dutta, Evan Cheng, G Valentin Börner, Michael Lichten, Nancy M Hollingsworth   +8 more
doaj   +1 more source

The molecular machinery of meiotic recombination. [PDF]

Biochem Soc Trans
Meiotic recombination, a cornerstone of eukaryotic diversity and individual genetic identity, is essential for the creation of physical linkages between homologous chromosomes, facilitating their faithful segregation during meiosis I. This process requires that germ cells generate controlled DNA lesions within their own genome that are subsequently ...
Chen L, Weir JR.
europepmc   +4 more sources

Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination [PDF]

, 2015
In meiotic DNA recombination, the Hop2-Mnd1 complex promotes Dmc1-mediated single-stranded DNA (ssDNA) invasion into homologous chromosomes to form a synaptic complex by a yet-unclear mechanism.
Dal Peraro, Matteo, Dal Peraro, M., Kalantzi, Alexandra-Styliani, Toseland, Christopher P., Oh, B., Shin, H.-C., Oh, Byung-Ha, M D Peraro, A S Kalantzi, Toseland, C.P., Shin, Ho-Chul, S Gruber, Kalantzi, A., Kang, H.-A., Kang, H., Toseland, C., Ho-Chul Shin, Gruber, Stephan, Kalantzi, A.-S., Oh, B.-H., Kim, H.-M., H A Kang, B H Oh, Kang, Hyun-Ah, Kim, Hyun-Min, Gruber, S., H M Kim, Shin, H., C P Toseland, Kim, H.   +29 more
core   +2 more sources

Meiotic recombination in Caenorhabditis elegans [PDF]

Chromosome Research, 2007
The faithful segregation of homologous chromosomes during meiosis is dependent on the formation of physical connections (chiasma) that form following reciprocal exchange of DNA molecules during meiotic recombination. Here we review the current knowledge in the Caenorhabditis elegans meiotic recombination field.
Tatiana, Garcia-Muse, Simon J, Boulton
openaire   +2 more sources

Recombination and its impact on the genome of the haplodiploid parasitoid wasp Nasonia [PDF]

, 2013
Homologous meiotic recombination occurs in most sexually reproducing organisms, yet its evolutionary advantages are elusive. Previous research explored recombination in the honeybee, a eusocial hymenopteran with an exceptionally high genome-wide ...
Gadau, Juergen, Gibson, Joshua D., Pannebakker, Bart A., Werren, John H., Koevoets, Tosca, Judson, Andrea K., van de Zande, Louis, Rosenberg, Michael S., Desjardins, Christopher A., Niehuis, Oliver, Kennedy, Kathleen, Duggan, David, Beukeboom, Leo W., Shuker, David Michael   +13 more
core   +3 more sources

Meiotic Synapsis in the Absence of Recombination [PDF]

Science, 1998
Although in Saccharomyces cerevisiae the initiation of meiotic recombination, as indicated by double-strand break formation, appears to be functionally linked to the initiation of synapsis, meiotic chromosome synapsis in Drosophila females occurs in the absence of meiotic exchange.
K S, McKim, B L, Green-Marroquin, J J, Sekelsky, G, Chin, C, Steinberg, R, Khodosh, R S, Hawley   +6 more
openaire   +2 more sources

Cytological analysis of MRE11 protein during early meiotic prophase I in Arabidopsis and tomato [PDF]

, 2008
Early recombination nodules (ENs) are multiprotein complexes that are thought to be involved in synapsis and recombination, but little is known about their components or how they may be involved in these events. In this study, we describe the cytological
Muyt, A., Lohmiller, L.D., Offenberg, H.H., Howard, B., Heyting, C., Grelon, M., Anderson, L.K.   +6 more
core   +1 more source

A simple model for the influence of meiotic conversion tracts on GC content. [PDF]

PLoS ONE, 2011
A strong correlation between GC content and recombination rate is observed in many eukaryotes, which is thought to be due to conversion events linked to the repair of meiotic double-strand breaks. In several organisms, the length of conversion tracts has
Marie-Claude Marsolier-Kergoat
doaj   +1 more source

H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis

Cell Reports, 2015
Meiotic recombination hotspots are associated with histone post-translational modifications and open chromatin. However, it remains unclear how histone modifications and chromatin structure regulate meiotic recombination. Here, we identify acetylation of
Jialei Hu, Greg Donahue, Jean Dorsey, Jérôme Govin, Zuofei Yuan, Benjamin A. Garcia, Parisha P. Shah, Shelley L. Berger   +7 more
doaj   +1 more source

Comparative transcriptomic analysis of thermally stressed Arabidopsis thaliana meiotic recombination mutants

BMC Genomics, 2021
Background Meiosis is a specialized cell division that underpins sexual reproduction in most eukaryotes. During meiosis, interhomolog meiotic recombination facilitates accurate chromosome segregation and generates genetic diversity by shuffling parental ...
Jiyue Huang, Hongkuan Wang, Yingxiang Wang, Gregory P. Copenhaver   +3 more
doaj   +1 more source