Results 11 to 20 of about 33,318 (207)

Hotspots for Initiation of Meiotic Recombination [PDF]

Frontiers in Genetics, 2018
Homologous chromosomes must pair and recombine to ensure faithful chromosome segregation during meiosis, a specialized type of cell division that occurs in sexually reproducing eukaryotes. Meiotic recombination initiates by programmed induction of DNA double-strand breaks (DSBs) by the conserved type II topoisomerase-like enzyme SPO11.
Tock, Andrew J, Henderson, Ian R
openaire   +5 more sources

Hybrid Sterility Locus on Chromosome X Controls Meiotic Recombination Rate in Mouse. [PDF]

PLoS Genetics, 2016
Meiotic recombination safeguards proper segregation of homologous chromosomes into gametes, affects genetic variation within species, and contributes to meiotic chromosome recognition, pairing and synapsis.
Maria Balcova, Barbora Faltusova, Vaclav Gergelits, Tanmoy Bhattacharyya, Ondrej Mihola, Zdenek Trachtulec, Corinna Knopf, Vladana Fotopulosova, Irena Chvatalova, Sona Gregorova, Jiri Forejt   +10 more
doaj   +1 more source

Identification and Expression of TOP3α in Gerbera hybrida

Horticultural Plant Journal, 2021
Meiotic recombination and the resulting novel allele combinations are fundamental to plant breeding and the identification of superior hybrids. However, the rate of meiotic crossovers is naturally suppressed below its potential ability, which prevents ...
Shenchong Li, Ying Cheng, Dan Sun, Lulin Ma, Mingyang Li, Fan Li   +5 more
doaj   +1 more source

Targeted Stimulation of Meiotic Recombination [PDF]

Cell, 2002
Meiotic recombination in Saccharomyces cerevisiae is initiated by programmed DNA double-strand breaks (DSBs), a process that requires the Spo11 protein. DSBs usually occur in intergenic regions that display open chromatin accessibility, but other determinants that control their frequencies and non-random chromosomal distribution remain obscure.
Pecina, A., Smith, K.N., Mezard, Christine, Murakami, Hitoshi, Ohta, K., Nicolas, A.   +5 more
openaire   +3 more sources

Dual roles of R-loops in the formation and processing of programmed DNA double-strand breaks during meiosis

Cell & Bioscience, 2023
Background Meiotic recombination is initiated by Spo11-dependent programmed DNA double-strand breaks (DSBs) that are preferentially concentrated within genomic regions called hotspots; however, the factor(s) that specify the positions of meiotic DSB ...
Chao Liu, Wei Xu, Liying Wang, Zhuo Yang, Kuan Li, Jun Hu, Yinghong Chen, Ruidan Zhang, Sai Xiao, Wenwen Liu, Huafang Wei, Jia-Yu Chen, Qianwen Sun, Wei Li   +13 more
doaj   +1 more source

ATM Promotes RAD51-Mediated Meiotic DSB Repair by Inter-Sister-Chromatid Recombination in Arabidopsis

Frontiers in Plant Science, 2020
Meiotic recombination ensures accurate homologous chromosome segregation during meiosis and generates novel allelic combinations among gametes. During meiosis, DNA double strand breaks (DSBs) are generated to facilitate recombination.
Yuan Yao, Xiaojing Li, Wanli Chen, Hui Liu, Limin Mi, Ding Ren, Aowei Mo, Pingli Lu   +7 more
doaj   +1 more source

Sex without crossing over in the yeast Saccharomycodes ludwigii

Genome Biology, 2021
Background Intermixing of genomes through meiotic reassortment and recombination of homologous chromosomes is a unifying theme of sexual reproduction in eukaryotic organisms and is considered crucial for their adaptive evolution.
Ioannis A. Papaioannou, Fabien Dutreux, France A. Peltier, Hiromi Maekawa, Nicolas Delhomme, Amit Bardhan, Anne Friedrich, Joseph Schacherer, Michael Knop   +8 more
doaj   +1 more source

Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase.

PLoS Genetics, 2022
During meiosis, recombination between homologous chromosomes (homologs) generates crossovers that promote proper segregation at the first meiotic division. Recombination is initiated by Spo11-catalyzed DNA double strand breaks (DSBs). 5' end resection of
Andrew Ziesel, Qixuan Weng, Jasvinder S Ahuja, Abhishek Bhattacharya, Raunak Dutta, Evan Cheng, G Valentin Börner, Michael Lichten, Nancy M Hollingsworth   +8 more
doaj   +1 more source

Meiotic recombination in Caenorhabditis elegans [PDF]

Chromosome Research, 2007
The faithful segregation of homologous chromosomes during meiosis is dependent on the formation of physical connections (chiasma) that form following reciprocal exchange of DNA molecules during meiotic recombination. Here we review the current knowledge in the Caenorhabditis elegans meiotic recombination field.
Tatiana, Garcia-Muse, Simon J, Boulton
openaire   +2 more sources

FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading. [PDF]

Nat Commun
During meiosis, nucleoprotein filaments of the strand exchange proteins RAD51 and DMC1 are crucial for repairing SPO11-generated DNA double-strand breaks (DSBs) by homologous recombination (HR).
Zainu A, Dupaigne P, Bouchouika S, Cau J, Clément JAJ, Auffret P, Ropars V, Charbonnier JB, de Massy B, Mercier R, Kumar R, Baudat F.   +11 more
europepmc   +2 more sources