Results 1 to 10 of about 61,461 (149)

A conserved filamentous assembly underlies the structure of the meiotic chromosome axis [PDF]

eLife, 2019
The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged.
Alan MV West, Scott C Rosenberg, Sarah N Ur, Madison K Lehmer, Qiaozhen Ye, Götz Hagemann, Iracema Caballero, Isabel Usón, Amy J MacQueen, Franz Herzog, Kevin D Corbett   +10 more
doaj   +6 more sources

Manipulation of Meiotic Recombination to Hasten Crop Improvement [PDF]

Biology, 2022
Reciprocal (cross-overs = COs) and non-reciprocal (gene conversion) DNA exchanges between the parental chromosomes (the homologs) during meiotic recombination are, together with mutation, the drivers for the evolution and adaptation of species.
Ian Fayos, Julien Frouin, Donaldo Meynard, Aurore Vernet, Léo Herbert, Emmanuel Guiderdoni   +5 more
doaj   +2 more sources

FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading [PDF]

Nature Communications
During meiosis, nucleoprotein filaments of the strand exchange proteins RAD51 and DMC1 are crucial for repairing SPO11-generated DNA double-strand breaks (DSBs) by homologous recombination (HR).
Akbar Zainu, Pauline Dupaigne, Soumya Bouchouika, Julien Cau, Julie A. J. Clément, Pauline Auffret, Virginie Ropars, Jean-Baptiste Charbonnier, Bernard de Massy, Raphael Mercier, Rajeev Kumar, Frédéric Baudat   +11 more
doaj   +2 more sources

Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions [PDF]

, 2013
During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation.
A Chavez, A De Muyt, A Hochwagen, A Hochwagen, A Irmisch, A McAleenan, A Schwacha, A Sourirajan, A Svetlanov, AC Chan, AJ Wood, AL Marston, Alex D. Herbert, Alice Copsey, Andreas Hochwagen, Andrew Chi-ho Chan, B Rockmill, BH Lee, C Buhler, C Tapia-Alveal, DM Sheedy, E Ampatzidou, EA Andrews, EA Outwin, ER Hoffmann, Eva Hoffmann, F Osman, FZ Watts, G De Piccoli, G Vader, GA Cromie, GR Smith, GV Borner, H Murakami, Hannah G. Blitzblau, HB Lindroos, HG Blitzblau, HG Blitzblau, HG Yu, HG Yu, I Lilienthal, J Gregan, J Matos, J Matos, J Palecek, J Pan, J Torres-Rosell, J Zalevsky, JA Carballo, JA Downs, JK Holloway, JM Murray, JR Mullen, JR Mullen, JS Bickel, K Nishimura, K Zakharyevich, K Zakharyevich, KA Henderson, KP Kim, KP Kohl, KT Nishant, L Jessop, L Jessop, L Newnham, L Wu, L Xu, LE Berchowitz, LE Hang, LJ Gaskell, Louise Newnham, M Bermudez-Lopez, M Xaver, MA Roy, Michael Lichten, MJ Neale, MN Boddy, MS McMahill, N Hunter, N Hunter, N Wu, Neil Hunter, NK Kolas, O Yildiz, P Jordan, Philip W. Jordan, PR Potts, PR Potts, Prakash Arumugam, RK Clyne, S Agarwal, S Chu, S Farmer, S Gray, S Panizza, S Pebernard, S Wehrkamp-Richter, SB Buonomo, SD Oh, SD Oh, Shangming Tang, SL Andersen, Sonya Newcombe, Stephen Gray, T de los Santos, T Snowden, T Wechsler, TM Carlile, TS Kitajima, V Kaliraman, WM Fricke, X Zhao, Y Blat, YH Chen, YH Chen, Zhaobo Li   +115 more
core   +19 more sources

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26

Biomolecules, 2022
Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 ...
Kouji Hirota
doaj   +1 more source

RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis.

PLoS Genetics, 2021
An essential component of the homologous recombination machinery in eukaryotes, the RAD54 protein is a member of the SWI2/SNF2 family of helicases with dsDNA-dependent ATPase, DNA translocase, DNA supercoiling and chromatin remodelling activities.
Miguel Hernandez Sanchez-Rebato, Alida M Bouatta, Maria E Gallego, Charles I White, Olivier Da Ines   +4 more
doaj   +1 more source

Evolution of the recombination regulator PRDM9 in minke whales

BMC Genomics, 2022
Background PRDM9 is a key regulator of meiotic recombination in most metazoans, responsible for reshuffling parental genomes. During meiosis, the PRDM9 protein recognizes and binds specific target motifs via its array of C2H2 zinc-fingers encoded by a ...
Elena Damm, Kristian K. Ullrich, William B. Amos, Linda Odenthal-Hesse   +3 more
doaj   +1 more source

Arabidopsis RAD51, RAD51C and XRCC3 proteins form a complex and facilitate RAD51 localization on chromosomes for meiotic recombination. [PDF]

PLoS Genetics, 2017
Meiotic recombination is required for proper homologous chromosome segregation in plants and other eukaryotes. The eukaryotic RAD51 gene family has seven ancient paralogs with important roles in mitotic and meiotic recombination.
Hang Su, Zhihao Cheng, Jiyue Huang, Juan Lin, Gregory P Copenhaver, Hong Ma, Yingxiang Wang   +6 more
doaj   +1 more source

The CAF-1 and Hir Histone Chaperones Associate with Sites of Meiotic Double-Strand Breaks in Budding Yeast. [PDF]

PLoS ONE, 2015
In the meiotic prophase, programmed DNA double-strand breaks (DSB) are introduced along chromosomes to promote homolog pairing and recombination. Although meiotic DSBs usually occur in nucleosome-depleted, accessible regions of chromatin, their repair by
Elsa Brachet, Claire Béneut, Maria-Elisabetta Serrentino, Valérie Borde   +3 more
doaj   +1 more source

M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination [PDF]

EMBO Reports, 2023
Yang Li, Ihsan Khan, Jianteng Zhou
exaly   +2 more sources