Results 31 to 40 of about 33,318 (207)

Separation of DNA replication from the assembly of break-competent meiotic chromosomes. [PDF]

PLoS Genetics, 2012
The meiotic cell division reduces the chromosome number from diploid to haploid to form gametes for sexual reproduction. Although much progress has been made in understanding meiotic recombination and the two meiotic divisions, the processes leading up ...
Hannah G Blitzblau, Clara S Chan, Andreas Hochwagen, Stephen P Bell   +3 more
doaj   +1 more source

Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination

Cell Reports, 2020
Summary: Meiotic recombination is critical for genetic exchange and generation of chiasmata that ensures faithful chromosome segregation during meiosis I.
Kazumasa Takemoto, Naoki Tani, Yuki Takada-Horisawa, Sayoko Fujimura, Nobuhiro Tanno, Mariko Yamane, Kaho Okamura, Michihiko Sugimoto, Kimi Araki, Kei-ichiro Ishiguro   +9 more
doaj   +1 more source

The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans.

PLoS Genetics, 2023
During meiotic prophase, the essential events of homolog pairing, synapsis, and recombination are coordinated with meiotic progression to promote fidelity and prevent aneuploidy.
Anna E Russo, Stefani Giacopazzi, Alison Deshong, Malaika Menon, Valery Ortiz, Kaori M Ego, Kevin D Corbett, Needhi Bhalla   +7 more
doaj   +1 more source

Local chromosome context is a major determinant of crossover pathway biochemistry during budding yeast meiosis

eLife, 2016
The budding yeast genome contains regions where meiotic recombination initiates more frequently than in others. This pattern parallels enrichment for the meiotic chromosome axis proteins Hop1 and Red1.
Darpan Medhi, Alastair SH Goldman, Michael Lichten   +2 more
doaj   +1 more source

Effect of Temperature and Maternal Age on Recombination Rate in Cattle

Frontiers in Genetics, 2021
Meiotic recombination is a fundamental biological process that facilitates meiotic division and promotes genetic diversity. Recombination is phenotypically plastic and affected by both intrinsic and extrinsic factors.
Botong Shen, Ellen Freebern, Jicai Jiang, Jicai Jiang, Christian Maltecca, John B. Cole, George E. Liu, Li Ma   +7 more
doaj   +1 more source

Meiotic recombination mechanisms

Comptes Rendus. Biologies, 2016
Meiosis is a specialized cell division at the origin of the haploid cells that eventually develop into the gametes. It therefore lies at the heart of Mendelian heredity. Recombination and redistribution of the homologous chromosomes arising during meiosis constitute an important source of genetic diversity, conferring to meiosis a particularly ...
openaire   +4 more sources

Meiotic Synapsis in the Absence of Recombination [PDF]

Science, 1998
Although in Saccharomyces cerevisiae the initiation of meiotic recombination, as indicated by double-strand break formation, appears to be functionally linked to the initiation of synapsis, meiotic chromosome synapsis in Drosophila females occurs in the absence of meiotic exchange.
K S, McKim, B L, Green-Marroquin, J J, Sekelsky, G, Chin, C, Steinberg, R, Khodosh, R S, Hawley   +6 more
openaire   +2 more sources

The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis.

PLoS Genetics, 2016
Meiotic recombination is essential for the repair of programmed double strand breaks (DSBs) to generate crossovers (COs) during meiosis. The efficient processing of meiotic recombination intermediates not only needs various resolvases but also requires ...
Ye Hong, Remi Sonneville, Ana Agostinho, Bettina Meier, Bin Wang, J Julian Blow, Anton Gartner   +6 more
doaj   +1 more source

Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes.

PLoS Genetics, 2020
Meiotic recombination is essential for faithful segregation of homologous chromosomes during gametogenesis. The progression of recombination is associated with dynamic changes in meiotic chromatin structures.
Kazumasa Takemoto, Yukiko Imai, Kenji Saito, Toshihiro Kawasaki, Peter M Carlton, Kei-Ichiro Ishiguro, Noriyoshi Sakai   +6 more
doaj   +1 more source

Dot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptor. [PDF]

PLoS Genetics, 2013
During meiosis, accurate chromosome segregation relies on the proper interaction between homologous chromosomes, including synapsis and recombination. The meiotic recombination checkpoint is a quality control mechanism that monitors those crucial events.
David Ontoso, Isabel Acosta, Fred van Leeuwen, Raimundo Freire, Pedro A San-Segundo   +4 more
doaj   +1 more source