Results 1 to 10 of about 169,076 (377)

Differential Antifungal Activity of Human and Cryptococcal Melanins with Structural Discrepancies [PDF]

Frontiers in Microbiology, 2017
Melanin is a pigment found in all biological kingdoms, and plays a key role in protection against ultraviolet radiation, oxidizing agents, and ionizing radiation damage. Melanin exerts an antimicrobial activity against bacteria, fungi, and parasites.
Néstor Correa, Néstor Correa, Néstor Correa, Cristian Covarrubias, Paula I. Rodas, Germán Hermosilla, Verónica R. Olate, Verónica R. Olate, Cristián Valdés, Wieland Meyer, Fabien Magne, Cecilia V. Tapia, Cecilia V. Tapia   +12 more
doaj   +3 more sources

Research progress on peptides that inhibit melanin synthesis [PDF]

Frontiers in Pharmacology
Melanin produced by melanocytes, primarily determines human skin color and protects against ultraviolet radiation. However, excessive melanin deposition can lead to skin conditions such as freckles, age spots, and moles, potentially causing aesthetic ...
Binrui Yu, Nailong Wang, Shanshan Cai, Hao Yan, Shaojia Sun, Siru Wang, Ye Li, Zhengting Liang   +7 more
doaj   +2 more sources

Fungal Melanin in Plant Pathogens: Complex Biosynthesis Pathways and Diverse Biological Functions [PDF]

Plants
Fungal melanin plays a vital role in the survival, reproduction, infection, and environmental adaptation of plant pathogenic fungi. To develop innovative strategies for managing plant fungal diseases, comprehensive investigations into melanin are ...
Hui Jia, Ning Liu, Lu Zhang, Pan Li, Yanan Meng, Wei Yuan, Haixiao Li, Dezeng Tantai, Qing Qu, Zhiyan Cao, Jingao Dong   +10 more
doaj   +2 more sources

High temporal-resolution transcriptome landscape reveals the biological process and regulatory genes of melanin deposition in breast muscle of Silkie chickens during embryonic development [PDF]

BMC Genomics
Background Abnormal deposition of melanin in skeletal muscle is an interesting phenomenon and the Silkie is the most typical example. Melanin deposition involves multiple steps such as neural crest cell migration, melanocyte differentiation, melanosome ...
Xinting Yang, Bowen Ma, Qingyu Zhao, Yaxiong Jia, Qingshi Meng, Yuchang Qin, Chaohua Tang, Junmin Zhang   +7 more
doaj   +2 more sources

Differential Induction of Reactive Oxygen Species and Expression of Antioxidant Enzymes in Human Melanocytes Correlate with Melanin Content: Implications on the Response to Solar UV and Melanoma Susceptibility

Antioxidants, 2022
Constitutive pigmentation determines the response to sun exposure and the risk for melanoma, an oxidative stress–driven tumor. Using primary cultures of human melanocytes, we compared the effects of constitutive pigmentation on their antioxidant response
Parth R. Upadhyay, Renny J. Starner, Viki B. Swope, Kazumasa Wakamatsu, Shosuke Ito, Zalfa A. Abdel-Malek   +5 more
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Predictors of self-reported research productivity amongst medical students in the United Kingdom: a national cross-sectional survey

BMC Medical Education, 2023
Background The number of academic clinicians in the UK is declining and there are demographic inequalities in the clinical-academic workforce. Increased research productivity by medical students is believed to reduce future attrition in the clinical ...
Temidayo Osunronbi, William Adeboye, David Faluyi, Jasmine Sofela, Efua Abankwa, Semhar Abraha, Fatima Adamu-Biu, Zain Ahmad, Izieduwa Akhionbare, Chimba Chimba, Anna Chiara Corriero, Isata J. Fofanah, Ikenna Ibeanusi, Ummulkhulsum Ibrahim, Deborah Inyang, Robert Jones, Adebola Kolawole, Rachael Madume, Chenai Mandangu, Valentine Mberu, Ellen Nelson-Rowe, Marguerite O’Riordan, Serena Shoker, Agbolahan Sofela, REMED-U. K. collaborators   +24 more
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Extraction and virulence analysis of melanin from Fonsecaea monophora

Pifu-xingbing zhenliaoxue zazhi, 2023
Objective To construct a mouse model of footpad inoculation with Fonsecaea monophora (F.monophora) melanin, and to analyze the differences in the virulence of F.monophora melanin from different sources.
Huan HUANG, Minying LI, Mingfen LUO, Yinghui LIU, Qian LI, Xiaoyue WANG, Dongmei LI, Hongfang LIU, Liyan XI   +8 more
doaj   +1 more source

Taphonomic experiments reveal authentic molecular signals for fossil melanins and verify preservation of phaeomelanin in fossils

Nature Communications, 2023
Melanin pigments play a critical role in physiological processes and shaping animal behaviour. Fossil melanin is a unique resource for understanding the functional evolution of melanin but the impact of fossilisation on molecular signatures for eumelanin
Tiffany S. Slater, Shosuke Ito, Kazumasa Wakamatsu, Fucheng Zhang, Peter Sjövall, Martin Jarenmark, Johan Lindgren, Maria E. McNamara   +7 more
doaj   +1 more source

The potential impact of melanosomal pH and metabolism on melanoma

Frontiers in Oncology, 2022
Melanin is synthesized in melanocytes and is transferred into keratinocytes to block the effects of ultraviolet (UV) radiation and is important for preventing skin cancers including melanoma.
Jaewon You, Maftuna Yusupova, Jonathan H. Zippin   +2 more
doaj   +1 more source

The role of melanin in the grapevine trunk disease pathogen Lasiodiplodia gilanensis

Phytopathologia Mediterranea, 2020
Lasiodiplodia (Botryosphaeriaceae) includes fungi that are considered among the most aggressive to grapevine, capable of causing cankers and necrotic lesions which eventually lead to death of host plants.
Edelweiss Airam RANGEL-MONTOYA, Marcos PAOLINELLI, Philippe ROLSHAUSEN, Rufina HERNANDEZ-MARTINEZ   +3 more
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