Results 1 to 10 of about 71,458 (290)

Ionizing radiation changes the electronic properties of melanin and enhances the growth of melanized fungi.

PLoS ONE, 2007
BackgroundMelanin pigments are ubiquitous in nature. Melanized microorganisms are often the dominating species in certain extreme environments, such as soils contaminated with radionuclides, suggesting that the presence of melanin is beneficial in their ...
Ekaterina Dadachova, Ruth A Bryan, Xianchun Huang, Tiffany Moadel, Andrew D Schweitzer, Philip Aisen, Joshua D Nosanchuk, Arturo Casadevall   +7 more
doaj   +3 more sources

Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications [PDF]

Journal of Fungi
Natural melanin biopolymers exhibit a variety of biological activities, but their commercial development is constrained by numerous factors, including high costs, unsustainable sources, the use of harmful solvents during extraction, and low extraction ...
Jiandong Tang, Hebin Shen, Wenyu Lv, Jingxuan Zhang, Junsheng Fu   +4 more
doaj   +2 more sources

Melanin [PDF]

Current Biology, 2020
Melanins are a unique class of pigments found throughout the biosphere with a wide variety of functions, structures, and presentations. Cordero and Casadevall highlight the wide range of places melanins are found and the diverse functions they play in nature.
Radames J B, Cordero, Arturo, Casadevall
openaire   +3 more sources

Differential Induction of Reactive Oxygen Species and Expression of Antioxidant Enzymes in Human Melanocytes Correlate with Melanin Content: Implications on the Response to Solar UV and Melanoma Susceptibility

Antioxidants, 2022
Constitutive pigmentation determines the response to sun exposure and the risk for melanoma, an oxidative stress–driven tumor. Using primary cultures of human melanocytes, we compared the effects of constitutive pigmentation on their antioxidant response
Parth R. Upadhyay, Renny J. Starner, Viki B. Swope, Kazumasa Wakamatsu, Shosuke Ito, Zalfa A. Abdel-Malek   +5 more
doaj   +1 more source

Predictors of self-reported research productivity amongst medical students in the United Kingdom: a national cross-sectional survey

BMC Medical Education, 2023
Background The number of academic clinicians in the UK is declining and there are demographic inequalities in the clinical-academic workforce. Increased research productivity by medical students is believed to reduce future attrition in the clinical ...
Temidayo Osunronbi, William Adeboye, David Faluyi, Jasmine Sofela, Efua Abankwa, Semhar Abraha, Fatima Adamu-Biu, Zain Ahmad, Izieduwa Akhionbare, Chimba Chimba, Anna Chiara Corriero, Isata J. Fofanah, Ikenna Ibeanusi, Ummulkhulsum Ibrahim, Deborah Inyang, Robert Jones, Adebola Kolawole, Rachael Madume, Chenai Mandangu, Valentine Mberu, Ellen Nelson-Rowe, Marguerite O’Riordan, Serena Shoker, Agbolahan Sofela, REMED-U. K. collaborators   +24 more
doaj   +1 more source

Extraction and virulence analysis of melanin from Fonsecaea monophora

Pifu-xingbing zhenliaoxue zazhi, 2023
Objective To construct a mouse model of footpad inoculation with Fonsecaea monophora (F.monophora) melanin, and to analyze the differences in the virulence of F.monophora melanin from different sources.
Huan HUANG, Minying LI, Mingfen LUO, Yinghui LIU, Qian LI, Xiaoyue WANG, Dongmei LI, Hongfang LIU, Liyan XI   +8 more
doaj   +1 more source

Taphonomic experiments reveal authentic molecular signals for fossil melanins and verify preservation of phaeomelanin in fossils

Nature Communications, 2023
Melanin pigments play a critical role in physiological processes and shaping animal behaviour. Fossil melanin is a unique resource for understanding the functional evolution of melanin but the impact of fossilisation on molecular signatures for eumelanin
Tiffany S. Slater, Shosuke Ito, Kazumasa Wakamatsu, Fucheng Zhang, Peter Sjövall, Martin Jarenmark, Johan Lindgren, Maria E. McNamara   +7 more
doaj   +1 more source

Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans [PDF]

Infection and Immunity, 1996
Melanin synthesis is associated with virulence for the pathogenic fungus Cryptococcus neoformans. Exposure of nonmelanized C. neoformans 4067 cells to 4 M guanidinium isothiocyanate followed by 6 M HCl at 100 degrees C resulted in complete solubilization of cellular structures. However, exposure of melanized C.
Y, Wang, P, Aisen, A, Casadevall
openaire   +2 more sources

The potential impact of melanosomal pH and metabolism on melanoma

Frontiers in Oncology, 2022
Melanin is synthesized in melanocytes and is transferred into keratinocytes to block the effects of ultraviolet (UV) radiation and is important for preventing skin cancers including melanoma.
Jaewon You, Maftuna Yusupova, Jonathan H. Zippin   +2 more
doaj   +1 more source

The role of melanin in the grapevine trunk disease pathogen Lasiodiplodia gilanensis

Phytopathologia Mediterranea, 2020
Lasiodiplodia (Botryosphaeriaceae) includes fungi that are considered among the most aggressive to grapevine, capable of causing cankers and necrotic lesions which eventually lead to death of host plants.
Edelweiss Airam RANGEL-MONTOYA, Marcos PAOLINELLI, Philippe ROLSHAUSEN, Rufina HERNANDEZ-MARTINEZ   +3 more
doaj   +1 more source