Results 1 to 10 of about 65,646 (171)

High temporal-resolution transcriptome landscape reveals the biological process and regulatory genes of melanin deposition in breast muscle of Silkie chickens during embryonic development [PDF]

BMC Genomics
Background Abnormal deposition of melanin in skeletal muscle is an interesting phenomenon and the Silkie is the most typical example. Melanin deposition involves multiple steps such as neural crest cell migration, melanocyte differentiation, melanosome ...
Xinting Yang, Bowen Ma, Qingyu Zhao, Yaxiong Jia, Qingshi Meng, Yuchang Qin, Chaohua Tang, Junmin Zhang   +7 more
doaj   +2 more sources

Neuroprotective effects of melanins and melanin derivatives from Calvatia Craniiformis and Xylaria plebeja against Parkinsonian toxins [PDF]

Scientific Reports
Fungal melanins have remarkable bioactivities, but their practical applications are limited, partly due to their hydrophobic nature. Melanin modification with amino acids was reported to improve their water solubility. This research aimed to extract, and
Duong Thuy Nguyen, Linh Phuong Nguyen Vo, Debby Mangelings, Ann Van Eeckhaut, Yvan Vander Heyden, Hanh T. M. Tran   +5 more
doaj   +2 more sources

Differential Induction of Reactive Oxygen Species and Expression of Antioxidant Enzymes in Human Melanocytes Correlate with Melanin Content: Implications on the Response to Solar UV and Melanoma Susceptibility

Antioxidants, 2022
Constitutive pigmentation determines the response to sun exposure and the risk for melanoma, an oxidative stress–driven tumor. Using primary cultures of human melanocytes, we compared the effects of constitutive pigmentation on their antioxidant response
Parth R. Upadhyay, Renny J. Starner, Viki B. Swope, Kazumasa Wakamatsu, Shosuke Ito, Zalfa A. Abdel-Malek   +5 more
doaj   +1 more source

Predictors of self-reported research productivity amongst medical students in the United Kingdom: a national cross-sectional survey

BMC Medical Education, 2023
Background The number of academic clinicians in the UK is declining and there are demographic inequalities in the clinical-academic workforce. Increased research productivity by medical students is believed to reduce future attrition in the clinical ...
Temidayo Osunronbi, William Adeboye, David Faluyi, Jasmine Sofela, Efua Abankwa, Semhar Abraha, Fatima Adamu-Biu, Zain Ahmad, Izieduwa Akhionbare, Chimba Chimba, Anna Chiara Corriero, Isata J. Fofanah, Ikenna Ibeanusi, Ummulkhulsum Ibrahim, Deborah Inyang, Robert Jones, Adebola Kolawole, Rachael Madume, Chenai Mandangu, Valentine Mberu, Ellen Nelson-Rowe, Marguerite O’Riordan, Serena Shoker, Agbolahan Sofela, REMED-U. K. collaborators   +24 more
doaj   +1 more source

Extraction and virulence analysis of melanin from Fonsecaea monophora

Pifu-xingbing zhenliaoxue zazhi, 2023
Objective To construct a mouse model of footpad inoculation with Fonsecaea monophora (F.monophora) melanin, and to analyze the differences in the virulence of F.monophora melanin from different sources.
Huan HUANG, Minying LI, Mingfen LUO, Yinghui LIU, Qian LI, Xiaoyue WANG, Dongmei LI, Hongfang LIU, Liyan XI   +8 more
doaj   +1 more source

Taphonomic experiments reveal authentic molecular signals for fossil melanins and verify preservation of phaeomelanin in fossils

Nature Communications, 2023
Melanin pigments play a critical role in physiological processes and shaping animal behaviour. Fossil melanin is a unique resource for understanding the functional evolution of melanin but the impact of fossilisation on molecular signatures for eumelanin
Tiffany S. Slater, Shosuke Ito, Kazumasa Wakamatsu, Fucheng Zhang, Peter Sjövall, Martin Jarenmark, Johan Lindgren, Maria E. McNamara   +7 more
doaj   +1 more source

The potential impact of melanosomal pH and metabolism on melanoma

Frontiers in Oncology, 2022
Melanin is synthesized in melanocytes and is transferred into keratinocytes to block the effects of ultraviolet (UV) radiation and is important for preventing skin cancers including melanoma.
Jaewon You, Maftuna Yusupova, Jonathan H. Zippin   +2 more
doaj   +1 more source

The role of melanin in the grapevine trunk disease pathogen Lasiodiplodia gilanensis

Phytopathologia Mediterranea, 2020
Lasiodiplodia (Botryosphaeriaceae) includes fungi that are considered among the most aggressive to grapevine, capable of causing cankers and necrotic lesions which eventually lead to death of host plants.
Edelweiss Airam RANGEL-MONTOYA, Marcos PAOLINELLI, Philippe ROLSHAUSEN, Rufina HERNANDEZ-MARTINEZ   +3 more
doaj   +1 more source

Structural Color Production in Melanin-based Disordered Colloidal Nanoparticle Assemblies in Spherical Confinement [PDF]

, 2021
Melanin is a ubiquitous natural pigment that exhibits broadband absorption and high refractive index. Despite its widespread use in structural color production, how the absorbing material, melanin, affects the generated color is unknown. Using a combined molecular dynamics and finite-difference time-domain computational approach, this paper ...
arxiv   +1 more source

Genome-wide association analysis reveal the genetic reasons affect melanin spot accumulation in beak skin of ducks

BMC Genomics, 2022
Background Skin pigmentation is a broadly appearing phenomenon of most animals and humans in nature. Here we used a bird model to investigate why melanin spot deposits on the skin.
Hehe Liu, Jianmei Wang, Jian Hu, Lei Wang, Zhanbao Guo, Wenlei Fan, Yaxi Xu, Dapeng Liu, Yunsheng Zhang, Ming Xie, Jing Tang, Wei Huang, Qi Zhang, Zhengkui Zhou, Shuisheng Hou   +14 more
doaj   +1 more source