Results 51 to 60 of about 80,543 (306)

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

open access: yesAdvanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu   +13 more
wiley   +1 more source

Melanin-concentrating hormone in peripheral circulation in the human [PDF]

open access: yes, 2017
Melanin-concentrating hormone (MCH) is a hypothalamic neuropeptide with a well-characterised role in energy homeostasis and emergent roles in diverse physiologic functions such as arousal, mood and reproduction.
Murray, J.F.   +5 more
core   +1 more source

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

open access: yesAdvanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu   +7 more
wiley   +1 more source

The role of melanin production in the survival of Vibrio cholerae in the marine environment [PDF]

open access: yes, 2006
Word processed copy.Includes bibliographical references (p. 141-165).The marine bacterium Vibrio cholerae produces pyomelanin through the catabolism of L-tyrosine to homogentisic acid.
Paul, Lynthia Vivienne
core  

Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions. [PDF]

open access: yes, 2014
Searching for depigmenting agents from natural sources has become a new direction in the cosmetic industry as natural products are generally perceived as relatively safer.
Christopher Cheng   +7 more
core   +1 more source

Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2022
Melanin is macromolecules which have been developed while oxidative polymerization of phenolic compounds. It has been found that the majority of marine organisms produce melanin pigment.
M I Sheefaa, Pitchiah Sivaperumal
doaj   +1 more source

Ambient Light‐Activatable Luminescent Particle‐Embedded Conformal Patch for Photochemical Tissue Bonding and Photobiomodulated Healing

open access: yesAdvanced Materials, EarlyView.
We report a wearable photonic patch integrating room light‐ and sunlight‐activatable luminescent particles (RSLPs) for both photochemical tissue bonding and photobiomodulation. RSLPs harvest ambient light and emit red luminescence to drive chlorin e6–mediated collagen crosslinking.
Kyungjoo Jo   +12 more
wiley   +1 more source

Functional Fibers in Soft Robotics: Advances in Material, Structural, and Systemic Tactics

open access: yesAdvanced Robotics Research, EarlyView.
Fiber‐form robotic systems offer a scalable pathway toward embodied intelligence in soft robotics. This review surveys functional fibers as material, structural, and systemic elements, highlighting advances in responsive materials, architectural programing, and fabrication strategies.
Joonhee Won   +5 more
wiley   +1 more source

Differential Antifungal Activity of Human and Cryptococcal Melanins with Structural Discrepancies

open access: yesFrontiers in Microbiology, 2017
Melanin is a pigment found in all biological kingdoms, and plays a key role in protection against ultraviolet radiation, oxidizing agents, and ionizing radiation damage. Melanin exerts an antimicrobial activity against bacteria, fungi, and parasites.
Néstor Correa   +12 more
doaj   +1 more source

Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip

open access: yesAdvanced Science, EarlyView.
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao   +3 more
wiley   +1 more source

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