Results 71 to 80 of about 27,981 (253)

Bioinspired Melanin‐Based Optically Active Materials

, 2020
Melanin is a widespread multifunctional biological pigment that has emerged as a promising platform for applications in coating, catalysis, energy, drug delivery, and medical therapy.
Shawkey, Matthew, Ming Xiao, Xiao, Ming, Ali Dhinojwala, Dhinojwala, Ali, Matthew D. Shawkey   +5 more
core   +1 more source

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

Melanin distribution from the dermal–epidermal junction to the stratum corneum: non-invasive in vivo assessment by fluorescence and Raman microspectroscopy

Scientific Reports, 2020
The fate of melanin in the epidermis is of great interest due to its involvement in numerous physiological and pathological processes in the skin. Melanin localization can be assessed ex vivo and in vivo using its distinctive optical properties.
B. P. Yakimov, E. A. Shirshin, J. Schleusener, A. S. Allenova, V. V. Fadeev, M. E. Darvin   +5 more
doaj   +1 more source

Melanin Upcycling: Creation of Polymeric Materials from Melanin Decomposition Products

Melanin is a widely occurring biopolymer and has been the subject of much research, especially in dermatology. However, from a resource perspective, melanin is still an unutilized biomass because of its complex three-dimensional cross-linked structure ...
Keiki Kishikawa (1591579), Toshihiko Matsuura (18414744), Michinari Kohri (1757962), Hironori Izawa (1634722), Takumi Morita (18414741)   +4 more
core   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

Advanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu, Zhou Jiang, Lin Chen, Gowena Ling Yi Goh, Weijing Li, Qian He, Xintong Chen, Rui Li, Yuxuan Liu, Ning Li, Tao Zhou, Peng Xu   +11 more
wiley   +1 more source

Neuroprotective effects of melanins and melanin derivatives from Calvatia Craniiformis and Xylaria plebeja against Parkinsonian toxins

Scientific Reports
Fungal melanins have remarkable bioactivities, but their practical applications are limited, partly due to their hydrophobic nature. Melanin modification with amino acids was reported to improve their water solubility. This research aimed to extract, and
Duong Thuy Nguyen, Linh Phuong Nguyen Vo, Debby Mangelings, Ann Van Eeckhaut, Yvan Vander Heyden, Hanh T. M. Tran   +5 more
doaj   +1 more source

Magnetic Properties of Melanin Doped with Copper Oxide Nanoparticles

Engineering Proceedings
In this study, the analysis of XRD patterns reveals that both natural melanin and copper oxide-doped melanin exhibit amorphous structures. The absence of new peaks for Cu2O confirms that the copper oxide nanoparticles are effectively integrated into the ...
Nawal Madkhali
doaj   +1 more source

Role of Melanin Chemiexcitation in Melanoma Progression and Drug Resistance

Frontiers in Oncology, 2020
Melanoma is the deadliest type of skin cancer. Human melanomas often show hyperactivity of nitric oxide synthase (NOS) and NADPH oxidase (NOX), which, respectively, generate nitric oxide (NO·) and superoxide (O2·−).
Sanjay Premi
doaj   +1 more source

Production of melanin by Aspergillus fumigatus

, 2004
Melanins, or melanin-like compounds, may play a role in the pathogenesis of a number of human fungal infections. This study investigated the production of melanin by the important opportunistic pathogen Aspergillus fumigatus. Conidia from A.
Sirida Youngchim, Youngchim, S, Andrew J. Hamilton, Morris-Jones, R., Hamilton, A.J., Morris-Jones, R, Hay, Roderick, Youngchim, S., Rachael Morris-jones, Roderick J. Hay, Hay, R J, Hamilton, A J   +11 more
core   +1 more source

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

Advanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan, Yate Huang, Junhao Zhang, Shudong Tian, Zhixing Li, Xuanwen Li, Yanchen Zhang, Dongmei Wang, Sihao Ye, Ming Jin, Neng Ling, Wentao Yan, Kaihui Nan, Wencan Wu   +13 more
wiley   +1 more source