Results 81 to 90 of about 80,543 (306)
Advanced Science, EarlyView.A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang +11 more
wiley +1 more source
Melanin Upcycling: Creation of Polymeric Materials from Melanin Decomposition Products [PDF]
Melanin is a widely occurring biopolymer and has been the subject of much research, especially in dermatology. However, from a resource perspective, melanin is still an unutilized biomass because of its complex three-dimensional cross-linked structure ...
Keiki Kishikawa (1591579) +4 more
core +1 more source
Structural analysis and spectroscopic characterization of melanin-alginate films
Chemical Physics ImpactIn this work, we present the spectroscopic and structural analysis of synthetic melanin incorporated within alginate films. We propose a synthesis methodology for alginate films with different concentrations of melanin.
Lidia Elizabeth Verduzco-Grajeda +4 more
doaj +1 more source
Advanced Science, EarlyView.Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou +10 more
wiley +1 more source
Scientific ReportsFungal melanins have remarkable bioactivities, but their practical applications are limited, partly due to their hydrophobic nature. Melanin modification with amino acids was reported to improve their water solubility. This research aimed to extract, and
Duong Thuy Nguyen +5 more
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Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
Advanced Science, EarlyView.While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source
Melaninas quimicamente modificadas: preparação, caracterização, citotoxicidade, atividade antioxidante e interação com espécies catiônicas [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015.Melaninas são bio-oligômeros de ocorrência natural que podem ser encontradas na pele, no cabelo,
Costa, Thiago Guimarães
core
Melanin-concentrating hormone and sleep. [PDF]
, 2017 The melanin-concentrating hormone (MCH) is an essential neuromodulator involved with homeostatic regulation and motivated behaviors. The majority of MCH neurons are localized within the zona incerta, lateral hypothalamic and incerto-hypothalamic areas ...
Jackson Cioni Bittencourt +5 more
core +1 more source
Remembering Keisuke Fujita, MD, PhD, President and Founder of Fujita Health University
Fujita Medical Journal, 2022 Shosuke Ito
doaj +1 more source
Advanced Science, EarlyView.The diagram illustrates a sustainable model of lignin valorization and carbon cycling based on microbial cell factories. Using lignin as the feedstock, synthetic biology technologies, including depolymerization, cell factory construction, pathway gene module integration, and metabolic network regulation, are applied to convert lignin into bulk ...
Na Li +4 more
wiley +1 more source