Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. [PDF]
PurposeThe RPE cell line ARPE-19 provides a dependable and widely used alternative to native RPE. However, replication of the native RPE phenotype becomes more difficult because these cells lose their specialized phenotype after multiple passages ...
Duncan, Todd +8 more
core +2 more sources
Thyroid hormone regulates distinct paths to maturation in pigment cell lineages [PDF]
Thyroid hormone (TH) regulates diverse developmental events and can drive disparate cellular outcomes. In zebrafish, TH has opposite effects on neural crest derived pigment cells of the adult stripe pattern, limiting melanophore population expansion, yet
Aman, Andrew J +10 more
core +1 more source
Recent era of research: Microbial melanin in life sciences
This review focuses on melanin pigment, its types, physical and chemical properties, melanogenesis, various microbial sources for melanin synthesis, current trends in melanin characterization, applications of melanin pigments in various fields, and ...
Rukaiyya Amjad Khatib +3 more
doaj
Melanized fungi are known for their remarkable resilience to environmental stress, largely attributed to the protective properties of melanin. In this study, we establish the black yeast Exophiala viscosa as a non-pathogenic, genetically tractable model ...
Tiffany M. Hennessa +8 more
doaj +1 more source
5,6-dihydroxyindole-2-carboxylic acid (DHICA): a First Principles Density-Functional Study
We report first principles density functional calculations for 5,6-dihydroxyindole-2-carboxylic acid (DHICA) and several reduced forms. DHICA and 5,6-dihydroxyindole (DHI) are believed to be the basic building blocks of the eumelanins.
B.J. Powell +29 more
core +1 more source
A histopathologic evaluation of gross lesions excised from commercially important North Altantic marine fishes [PDF]
Histopathologic studies of lesions found in commercially important North Atlantic marine fishes are uncommon. As part of a comprehensive Northeast Fisheries Center program ("Ocean Pulse") to evaluate environmental and resource health on the U.S ...
Despres-Patanjo, Linda +2 more
core
AbstractMelanin is responsible, in Nature, for photoprotection, for this reason it is expected to be poorly photoreactive. However, the photo‐reactivity of melanin and related materials is well documented. Here we discuss some relevant recent examples to demonstrate that, indeed, the actual mechanism of interaction of melanin with light is complex and ...
Menichetti A., Mordini D., Montalti M.
openaire +2 more sources
Secondary metabolism of the forest pathogen Dothistroma septosporum : a thesis presented in the partial fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Genetics at Massey University, Manawatu, New Zealand [PDF]
Dothistroma septosporum is a fungus causing the disease Dothistroma needle blight (DNB) on more than 80 pine species in 76 countries, and causes serious economic losses. A secondary metabolite (SM) dothistromin, produced by D. septosporum, is a virulence
Ozturk, Ibrahim Kutay
core
Melanin is ubiquitous in nature, and how the arrangement and concentration of melanin affect its optical and thermal properties aids in understanding the role of melanin in natural systems and technological applications.
Hanieh Mohsenzadeh Hedeshi +6 more
doaj +1 more source
Application of melanin and its engineered nanomaterials in tumor radiotherapy: a review. [PDF]
Chen C, Guo Y.
europepmc +1 more source

