Results 101 to 110 of about 21,081 (324)
The Toxicity of Melanin Precursors
Journal of Investigative Dermatology, 1978 The quinone intermediates resulting from tyrosinase-mediated oxidation of tyrosine were evaluated as sulfhydryl reagent inhibitors of purified calf thymus DNA polymerase alpha in order to determine which of these might be cytotoxic. Dopachrome and an oxidation product of 2,4,5-trihydroxyphenylalanine were relatively ineffective as inhibitors of DNA ...
Sylvia M. Tiffany +2 more
openaire +3 more sources
Cationic Peptoids for Systemic In Vivo Cartilage‐Targeting
Advanced Science, EarlyView.Systemically‐dosed Cy5‐labeled cationic peptoid probe (NlysO)7 (yellow) binds to the cartilage's glycosaminoglycan content in vivo across the entire body of a neonatal mouse imaged by light sheet fluorescence microscopy, revealing fluorescence uptake in generic cartilage as well as the developing and ossifying bones.
Chaonan Zhang +6 more
wiley +1 more source
SPECTRAL PROPERTIES OF TWO WATER-SOLUBLE MELANINS [PDF]
Biotechnologia ActaAim. The work was purposed to study the spectral properties of two types of water-soluble melanins to clarify the nature of the optical absorption and emission centers in them. Materials and methods.
V.M. Kravchenko +8 more
doaj +1 more source
Metal‐Ligand Complexes as Multifunctional Platforms for Photo‐Activated Cancer Therapy
Advanced Science, EarlyView.Metal‐ligand complexes serve as multifunctional platforms for photo‐activated cancer therapy, facilitating photothermal and photodynamic effects through light absorption and reactive oxygen species generation. This review categorizes these complexes by ligand and metal types, examines their roles in combined therapeutic approaches, and explores ...
Jeonga Kim, Saehan Choi, Yoonsung Nam
wiley +1 more source
Identification of 180 million years old, probably unchanged melanine [PDF]
The comparison of the infrared spectra of recent sepia melanine and of the content of the ink sac of fossilized cuttlefish indicates that the 180 million years old substance is unchanged melanine. Both substances behave identically on heating.
Beyermann, K., Hasenmaier, D.
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Free amino acids in a cave beetle \u3cem\u3eDarlingtonea kentuckensis\u3c/em\u3e Valentine (Coleoptera: Carabidae) [PDF]
, 1974 Free amino acids of Darlingtonea kentuckensis were investigated by two-dimensional, thin-layer chromatography on Silica Gel G. Thirteen amino acids which could be identifìed (alanine, glutamic acid, glycine, histidine, isoleucine and/or leucine, lysine ...
Sperka, R. J.
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Fundamental building blocks of eumelanins: electronic properties of indolequinone-dimers
, 2003 We present results from the theoretical INDO calculations of the electronic structure for stacked eumelanins' monomers. As basic indolic components of the eumelanin structure 5,6-dihydroxyindole (DHI or HQ) and its oxidized forms (SQ and IQ) were chosen.
Bochenek +16 more
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Chemistry – A European JournalAbstractMelanin is responsible, in Nature, for photoprotection, for this reason it is expected to be poorly photoreactive. However, the photo‐reactivity of melanin and related materials is well documented. Here we discuss some relevant recent examples to demonstrate that, indeed, the actual mechanism of interaction of melanin with light is complex and ...
Menichetti A., Mordini D., Montalti M.
openaire +2 more sources
Advanced Science, EarlyView.This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang +13 more
wiley +1 more source
Carotenoids and their importance in the nutrition of fish and crustaceans [PDF]
, 1987 Carotenoids are quantitatively very prominent among the substances which render colour - Biochrome. There are an immense array of carotenoids in the animal kingdom and so also in the plants.
Easterson, D C V
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